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OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

The first results from the POISE biopsy sub-study have today confirmed that long-term treatment with obeticholic acid leads to the reversal or stabilization of fibrosis/cirrhosis in patients with primary biliary cholangitis who have had an incomplete response to ursodeoxycholic acid.

13 Apr 2018

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

The final results of the palliative cohort of the SORAMIC study in patients with unresectable, locally advanced primary liver cancer have confirmed no clinical advantage to adding selective internal radiation therapy to standard sorafenib treatment compared with using sorafenib alone.

13 Apr 2018

Researchers find possible therapeutic strategy to block self-eating in pancreatic cancers

To get the extra energy they need to fuel their uncontrolled growth, cancer cells break down some of their own parts for fuel - a process known as autophagy, or "self-eating."

13 Apr 2018

Omega-3 supplements found to be ineffective in alleviating dry eye symptoms

More than 16 million Americans suffer from dry eye, an often chronic condition that causes burning, itching, or stinging sensations in the eye, as well as impaired vision.

13 Apr 2018

'Night owls' have higher risk of early death than 'larks'

"Night owls" - people who like to stay up late and have trouble dragging themselves out of bed in the morning - have a higher risk of dying sooner than "larks," people who have a natural preference for going to bed early and rise with the sun, according to a new study from Northwestern Medicine and the University of Surrey in the United Kingdom.

13 Apr 2018

Diabetes screening could miss more than half of high-risk patients

Screening patients for diabetes based solely on their age and weight – a recommendation from a leading medical expert group – could miss more than half of high-risk patients, according to a new Northwestern Medicine study of a nationwide sample.

13 Apr 2018

Experimental molecular therapy to block matrix-forming protein may prevent heart failure

Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure.

13 Apr 2018

Protein linked with Alzheimer's disease affects different brain cells differently

Amyloid beta, a protein linked with Alzheimer's disease, has different properties in different cell types in the brains of fruit flies.

13 Apr 2018

Research reveals immune suppressive role of soluble antibodies in tumor progression

Wistar researchers have found that soluble antibodies promote tumor progression by inducing accumulation of myeloid-derived suppressor cells (MDSCs) in pre-clinical cancer models. Results were published online in Cancer Immunology Research.

13 Apr 2018

Oxygen 'nanobubbles' could help enhance cancer therapies and hasten wound healing

A Purdue University-patented technology shows promise in using microscopic bubbles filled with oxygen to help with various medical treatments, including improving cancer therapeutics and helping wounds heal faster.

13 Apr 2018

Researchers unlock new way to use cell's nanostructures as disease biomarkers

Researchers at the University of Sydney have established a method to identify individual nanoparticles released by human cells, opening the way for them to become diagnostic tools in the early-detection of cancers, dementia and kidney disease.

13 Apr 2018

Reducing sedentary behavior may be possible target to improve brain health

Sitting too much is linked to changes in a section of the brain that is critical for memory, according to a preliminary study by UCLA researchers of middle-aged and older adults.

12 Apr 2018

Researchers developing affordable, compact white blood cell counter

A thin copper wire wrapped around a channel slightly thicker than a strand of hair could be the key to manufacturing a compact electronic device capable of counting white blood cells from the comfort of one's home, a Kennesaw State University researcher says.

12 Apr 2018

KU Cancer Center to present evidence supporting anti-cancer drug at AACR 2018

The University of Kansas Cancer Center will present preclinical evidence supporting Ciclopirox Prodrug (CPX-POM), an anti-cancer agent currently in Phase I clinical trials, at the American Association for Cancer Research 2018 Annual Meeting in Chicago. Ciclopirox Prodrug was discovered by researchers at The University of Kansas Cancer Center and KU's Institute for Advancing Medical Innovation.

12 Apr 2018

New 'lymphoma micro-reactor' device targets chemo-resistant tumors

Non-Hodgkin lymphoma, a cancer that is diagnosed in the U.S. more than 70,000 times annually, arises from overly proliferating immune cells within the body's lymph nodes, which are connected to a network of lymph vessels through which lymphatic fluid flows.

12 Apr 2018

People with rare dementia may employ intact brain areas for help with language

People with a rare dementia that initially attacks the language center of the brain recruit other areas of the brain to decipher sentences, according to new research led by a University of Arizona cognitive scientist.

12 Apr 2018

New, sensitive HBV assay may allow earlier detection of hepatocellular carcinoma

Chronic hepatitis B virus (HBV) can progress to cirrhosis and hepatocellular carcinoma (HCC). A study published in The Journal of Molecular Diagnostics describes a new HBV assay that offers advantages over currently used methods because it has the capability to detect closed circular DNA (cccDNA) in serum, single cells, and preserved tissue samples.

12 Apr 2018

Researchers review potential of targeted nanocarriers to revolutionize cancer care

A new Tel Aviv University study addresses the challenges of nanoparticle-based cancer-targeting strategies. It also suggests ways of refocusing the collaborative work of cancer researchers and clinicians to move the field forward from "the bench" to the patients.

12 Apr 2018

CU Anschutz scientists receive $3.8 million DoD grant to boost EB research

Scientists from the Gates Center for Regenerative Medicine at the University of Colorado School of Medicine are part of a consortium awarded $3.8 million from the U.S. Department of Defense to move discoveries in stem cell-created skin grafts into the manufacturing stage, bringing further hope to victims of debilitating inherited skin diseases.

12 Apr 2018

Targeting metabolism of key nutrients could be effective in treating squamous cell carcinoma

Researchers from UCLA and Long Beach Memorial Medical Center have found that two targeted therapies could be more effective if used in combination to treat squamous cell carcinomas of the lung.

12 Apr 2018

Medical Condition News

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

Researchers find possible therapeutic strategy to block self-eating in pancreatic cancers

Omega-3 supplements found to be ineffective in alleviating dry eye symptoms

'Night owls' have higher risk of early death than 'larks'

Diabetes screening could miss more than half of high-risk patients

Experimental molecular therapy to block matrix-forming protein may prevent heart failure

Protein linked with Alzheimer's disease affects different brain cells differently

Research reveals immune suppressive role of soluble antibodies in tumor progression

Oxygen 'nanobubbles' could help enhance cancer therapies and hasten wound healing

Researchers unlock new way to use cell's nanostructures as disease biomarkers

Reducing sedentary behavior may be possible target to improve brain health

Researchers developing affordable, compact white blood cell counter

KU Cancer Center to present evidence supporting anti-cancer drug at AACR 2018

New 'lymphoma micro-reactor' device targets chemo-resistant tumors

People with rare dementia may employ intact brain areas for help with language

New, sensitive HBV assay may allow earlier detection of hepatocellular carcinoma

Researchers review potential of targeted nanocarriers to revolutionize cancer care

CU Anschutz scientists receive $3.8 million DoD grant to boost EB research

Targeting metabolism of key nutrients could be effective in treating squamous cell carcinoma

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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