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CRISPR technique reduces repetitive behavior in fragile X syndrome mouse models

Scientists have used CRISPR-Cas9 gene editing to lessen some autism symptoms in mice with a form of fragile X syndrome, the most common known single-gene cause of autism spectrum disorder.

25 Jun 2018

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

AbbVie , a research-based global biopharmaceutical company, and Calibr, a nonprofit drug discovery division of Scripps Research, today announced a collaboration to develop T-cell therapies aimed primarily at cancer, including solid tumors.

25 Jun 2018

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

A tumor's goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate.

25 Jun 2018

Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

Chemical compounds produced by gut bacteria could help spot early stages of liver disease

Chemical compounds produced by the bacteria in our gut could be used to spot the early stages of liver disease, according to new research.

25 Jun 2018

Researchers work on new treatment that could improve lives of cystic fibrosis patients

Researchers at Oregon State University and Oregon Health & Science University are working on a treatment that holds great promise for improving the lives of cystic fibrosis patients.

25 Jun 2018

New discovery suggests potential target for treating cancers and other diseases

When cells grow and divide to ensure a biological function - such as a properly working organ - DNA must be unwound from its typical tightly packed form and copied into RNA to create proteins.

25 Jun 2018

Eye could be a surrogate for brain degeneration like AD

Researchers from Queen's University Belfast have shown for the first time that the eye could be a surrogate for brain degeneration like Alzheimer's disease (AD).

25 Jun 2018

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Cedars-Sinai has launched an initiative to accelerate the development of novel drugs, devices and therapies aimed at improving treatments for patients with gastrointestinal and metabolic diseases.

25 Jun 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

New tests accurately detect heart disease and adverse cardiac events in diabetic patients

Prevencio, Inc. today announces data which indicates its HART CAD and HART CVE tests accurately diagnose Coronary Artery Disease and risk for Major Adverse Cardiac Events in Diabetic Mellitus patients.

25 Jun 2018

Study links molecular changes in the brain to key behaviors in addiction

Changes in a brain signaling system contribute to the development of alcohol addiction-like behaviors in rats, according to a new study led by researchers at Linköping University, Sweden.

25 Jun 2018

Lund researchers develop fluorescent variant of a molecule that inhibits cancer stem cells

A team of researchers at Lund University in Sweden has developed a fluorescent variant of a molecule that inhibits cancer stem cells.

25 Jun 2018

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

Pancreatic cancer is lethal in about 95% of cases mostly due to failure of first-line therapy gemcitabine. AntiCancer Inc.'s oral methioninase (AC 00619), which is in late pre-clinical development as an anti-cancer as well as an anti-aging drug, has now been shown to overcome gemcitabine resistance in mouse models of human pancreatic cancer, including AntiCancer's patient-derived orthotopic xenograft mouse models.

25 Jun 2018

Scientists identify immune cells that remove degenerating neurons after brain injury

Researchers have identified the immune cells that are responsible for clearing dead and dying nerve cells following a brain injury.

25 Jun 2018

Whisk's innovative Culinary Coach selected as winner of Ascensia Diabetes Challenge

Today, at the American Diabetes Association’s 78th Scientific Sessions in Orlando, Florida, Ascensia Diabetes Care has revealed that UK-based Whisk have been selected as the winner of the Ascensia Diabetes Challenge, a global innovation competition that set out to find digital solutions to support type 2 diabetes management.

25 Jun 2018

Mice learn to plan ahead and avoid future regrets

Experiencing regret can leave a “bad taste” in one’s mouth and drive an individual to compensate for one’s losses. This immediate post-regret phenomenon was once thought to be unique to humans, but it has been recently demonstrated in other species. However, it was previously unknown if other species are capable of learning from these mistakes over time.

25 Jun 2018

Risk of heart attacks, strokes and vascular occlusions found to be higher in cancer patients

It is well known that pre-existing cancer is a significant risk factor for venous thrombosis. What was hitherto unclear was whether cancer also has a negative impact upon the risk of heart attacks, strokes or occlusions of peripheral arteries.

25 Jun 2018

Studying The Effects of Microgravity on Muscle Mass

Studying the effects of gravity on muscle cells can give us an insight into muscle wastage diseases, and potentially guide the development of new therapies. Professor Louis Yuge discusses his research and the cellular changes that occur in response to microgravity.

25 Jun 2018

Newly developed model of retina can predict outcome of perturbation with high precision

Our eye hosts a powerful biological computer, the retina. Understanding how the retina transforms images from the outside world into signals that the brain can interpret would not only result in insights into brain computations, but could also be useful for medicine.

25 Jun 2018

Medical Condition News

CRISPR technique reduces repetitive behavior in fragile X syndrome mouse models

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

Researchers discover immune profile for effective cancer immunotherapy

Chemical compounds produced by gut bacteria could help spot early stages of liver disease

Researchers work on new treatment that could improve lives of cystic fibrosis patients

New discovery suggests potential target for treating cancers and other diseases

Eye could be a surrogate for brain degeneration like AD

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

New tests accurately detect heart disease and adverse cardiac events in diabetic patients

Study links molecular changes in the brain to key behaviors in addiction

Lund researchers develop fluorescent variant of a molecule that inhibits cancer stem cells

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

Scientists identify immune cells that remove degenerating neurons after brain injury

Whisk's innovative Culinary Coach selected as winner of Ascensia Diabetes Challenge

Mice learn to plan ahead and avoid future regrets

Risk of heart attacks, strokes and vascular occlusions found to be higher in cancer patients

Studying The Effects of Microgravity on Muscle Mass

Newly developed model of retina can predict outcome of perturbation with high precision

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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