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First-in-human phase 0 study shows clinically-relevant activity of new drug in glioblastoma

Combating glioblastoma remains a major challenge due the complex nature of these tumors, the inability of drugs to penetrate the brain tissue, and lack of correlation between animal models and the human condition.

21 Sep 2018

Study opens new avenues for treatment of Laing distal myopathy

New avenues are now being opened for future treatment of Laing distal myopathy, a rare disorder that causes muscles in the feet, hands and elsewhere to atrophy. In a study published in the journal PNAS, researchers have identified an enzyme with a clear link to how the disease develops.

21 Sep 2018

Study explores connection between sexuality and cognitive status in older adults

The number of people who live at home with Alzheimer's Disease (AD), a brain disease that causes abnormal changes that kill brain cells, is expected to grow from 3.2 million today to more than 8 million in 2050.

21 Sep 2018

$CHMP grants positive opinion for VENCLYXTO plus rituximab for treating relapsed/refractory CLL$

CHMP grants positive opinion for VENCLYXTO plus rituximab for treating relapsed/refractory CLL

AbbVie, a research-based global biopharmaceutical company, announced today that the Committee for Medicinal Products for Human Use of the European Medicines Agency has granted a positive opinion for VENCLYXTO® in combination with rituximab for the treatment of patients with relapsed/refractory chronic lymphocytic leukemia who have received at least one prior therapy.

21 Sep 2018

CHMP issues positive opinion supporting use of Trelegy Ellipta in broader group of COPD patients

GlaxoSmithKline plc and Innoviva, Inc. announced that the European Medicines Agency's Committee for Medicinal Products for Human Use has issued a positive opinion today supporting the use of Trelegy Ellipta in a broader group of patients with moderate to severe chronic obstructive pulmonary disease and that labeling, if approved, will be updated to further reflect its effect on exacerbations of COPD.

21 Sep 2018

New clinical trial evaluates aesthetic results of conservative surgery in breast cancer

Belén Merck Navarro, Medicine professor at Valencia and Castellón's CEU UCH university is the only Spaniard among the 17 surgeons from 11 different countries that specialize in breast cancer who took part in a clinical trial on the usefulness of 3D images to evaluate the aesthetic results of conservative surgery in breast cancer

21 Sep 2018

Air pollution appears to be linked to increased risk of developing dementia

According to a new study co-authored by Professor Frank Kelly, School of Population Health & Environmental Sciences, air pollution appears to be linked to an increased risk of developing dementia.

21 Sep 2018

Bad air and inadequate data prove an unhealthy mix

Kira Hinslea wanted to play outside, but she knew she couldn't until her mom checked an air-quality app on her phone.

21 Sep 2018

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

Ipsen announced today that the Committee for Medicinal Products for Human Use, the scientific committee of the European Medicines Agency, provided a positive opinion for Cabometyx (cabozantinib) as a monotherapy for the treatment of hepatocellular carcinoma in adults who have been previously treated with sorafenib.

21 Sep 2018

TINY cancer detection device shows promise as point-of-care detector of KSHV

Its name is an acronym used to convey its size, but researchers at Cornell Engineering and Weill Cornell Medicine are hoping their hand-held cancer detection device's impact in the developing world is anything but small.

21 Sep 2018

Dopamine neurons may involve in conditions ranging from Parkinson's disease to schizophrenia

Dopamine neurons are located in the midbrain, but their tendril-like axons can branch far into the higher cortical areas, influencing how we move and how we feel.

21 Sep 2018

UAB researchers study dysfunction of the immune system associated with NSAID carprofen

Non-steroidal anti-inflammatory drugs, or NSAIDs, are commonly used as inflammation blockers worldwide. However, recent clinical data show these painkillers can have serious side effects that create some risk of heart attacks, strokes, and kidney or heart failure.

21 Sep 2018

New research finds that MHC-II molecules have more influence on tumors than MHC-I

Cancer immunotherapy -- efforts to boost a patient's own immune system, allowing it to better fight cancer cells on its own -- has shown great promise for some previously intractable cancers.

21 Sep 2018

Study reveals promising new drug candidate to treat acute renal failure

A protein produced by the human body appears to be a promising new drug candidate to treat conditions that lead to acute renal failure. This is shown by a study conducted at São Paulo State University in São José do Rio Preto, Brazil.

20 Sep 2018

Immediate compression therapy could cut risk of complications after deep-vein thrombosis

People with deep-vein thrombosis can substantially cut their risk of potentially debilitating complications by starting adequate compression therapy in the first twenty-four hours of DVT therapy (known as the acute phase of treatment), suggests a study published today in the journal Blood.

20 Sep 2018

Grieving patients treated with talk therapy have lower risk of suicide and psychiatric illness

In a comprehensive study, researchers from Aarhus University show that grieving patients who receive what is known as talk therapy at the general practitioner shortly after a relative's death, have a lower risk of suicide and psychiatric illness than others.

20 Sep 2018

Brain region for stress control is enlarged in people with depression, finds study

According to the World Health Organization, 322 million people worldwide were affected by depression in 2015--4.4 percent of the world's population.

20 Sep 2018

First evaluation of benefits, harms of Alzheimer's screening for family members of older adults

With the support of a new $3 million, five-year National Institute on Aging grant, researchers from the Regenstrief Institute and Indiana University Center for Aging Research are conducting the first evaluation of the benefits and harms of Alzheimer's disease screening for family members of older adults.

20 Sep 2018

Scientists predict how well the body will fight lung cancer by analyzing immune cell shapes

Researchers at Case Western Reserve University have discovered how to quickly and accurately predict which lung cancer patients will benefit from chemotherapy by analyzing how immune cells the body sends out to fight the disease are arranged.

20 Sep 2018

CWRU receives NIH grant to learn how non-coding genes contribute to spread of colorectal cancer

Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding genes also contribute to the development and spreading of the disease, one of the first known examples of researchers doing so.

20 Sep 2018

Medical Condition News

First-in-human phase 0 study shows clinically-relevant activity of new drug in glioblastoma

Study opens new avenues for treatment of Laing distal myopathy

Study explores connection between sexuality and cognitive status in older adults

CHMP grants positive opinion for VENCLYXTO plus rituximab for treating relapsed/refractory CLL

CHMP issues positive opinion supporting use of Trelegy Ellipta in broader group of COPD patients

New clinical trial evaluates aesthetic results of conservative surgery in breast cancer

Air pollution appears to be linked to increased risk of developing dementia

Bad air and inadequate data prove an unhealthy mix

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

TINY cancer detection device shows promise as point-of-care detector of KSHV

Dopamine neurons may involve in conditions ranging from Parkinson's disease to schizophrenia

UAB researchers study dysfunction of the immune system associated with NSAID carprofen

New research finds that MHC-II molecules have more influence on tumors than MHC-I

Study reveals promising new drug candidate to treat acute renal failure

Immediate compression therapy could cut risk of complications after deep-vein thrombosis

Grieving patients treated with talk therapy have lower risk of suicide and psychiatric illness

Brain region for stress control is enlarged in people with depression, finds study

First evaluation of benefits, harms of Alzheimer's screening for family members of older adults

Scientists predict how well the body will fight lung cancer by analyzing immune cell shapes

CWRU receives NIH grant to learn how non-coding genes contribute to spread of colorectal cancer

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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