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Discovery suggests new approach for targeting most-wanted molecular culprits in cancer

A discovery by scientists at Dana-Farber Cancer Institute and University of Texas Southwestern Medical Center presents drug developers with an entirely new tack in targeting one of the most-wanted molecular culprits in cancer.

12 Jan 2018

Researchers use novel PET tracer to assess myelin damage in mouse models of MS

The loss or damage of myelin, a cellular sheath that surrounds and insulates nerves, is the hallmark of the immune-mediated neurological disorder multiple sclerosis.

12 Jan 2018

Groundbreaking report highlights plan to end bowel cancer

A groundbreaking report, led by Professor Mark Lawler, Chair in Translational Cancer Genomics at Queen's University Belfast highlights a plan to end bowel cancer, the second most common cause of cancer death in Europe.

12 Jan 2018

Evidence suggests two patterns of early symptoms precede and predict later BD risk

Two patterns of antecedent or "prodromal" psychiatric symptoms may help to identify young persons at increased risk of developing bipolar disorder (BD), according to a new analysis in the Harvard Review of Psychiatry.

12 Jan 2018

Genetic analysis can enhance outcomes of depression treatment

The failure of drugs such as SSRIs, used to treat depression, can be a result of genetic variations in patients.

12 Jan 2018

FAU researchers show that fiber-rich diet has positive effect on inflammatory joint diseases

It is well known that healthy eating increases our general sense of wellbeing. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have now discovered that a fiber-rich diet can have a positive influence on chronic inflammatory joint diseases, leading to stronger bones.

12 Jan 2018

Study finds overall pattern of commonality between Huntington's and Parkinson's

A new study strongly suggests that the brains of people who have died of Huntington's disease (HD) and Parkinson's disease (PD) show a similar response to a lifetime of neurodegeneration, despite being two very distinct diseases.

12 Jan 2018

Heart failure patients who have anorexia have worse prognosis

Researchers of the German Centre for Cardiovascular Research (DZHK) have discovered that patients with heart failure who have anorexia are also more affected in their physical functional capacity and have worse prognosis.

12 Jan 2018

Worsening of anxiety symptoms may be early indicator of Alzheimer's disease

A new study suggests an association between elevated amyloid beta levels and the worsening of anxiety symptoms. The findings support the hypothesis that neuropsychiatric symptoms could represent the early manifestation of Alzheimer's disease in older adults.

12 Jan 2018

New drug candidates may offer breakthrough in treatment of COPD

The study was a cooperative effort between the team headed by assistant professor Dr Jürgen Knobloch from the Medical Clinic III for Pneumology, Sleep and Respiratory Medicine at the Bergmannsheil University Hospital in Bochum, Germany, and Prof Dr Andrea Koch, member of the German Center for Lung Research, previously in Bochum, now at the Medical Clinic V for Pneumology at the LMU University Hospital in Munich, as well as a team from the company RespiVert Ltd, a subsidiary of Janssen Biotech Inc., and Prof Dr Erich Stoelben from the Lung Clinic in Köln-Merheim.

12 Jan 2018

Study suggests shared genetic susceptibility to epilepsy and mood disorders

Mood disorders, including depression, are the most common comorbid conditions in individuals with epilepsy, but the cause remains unclear, according to a latest study by researchers at Columbia University's Mailman School of Public Health and Rutgers University.

12 Jan 2018

RAS dimers essential for causing cancer, study shows

Mutated RAS genes are some of the most common genetic drivers of cancer, especially in aggressive cancers like pancreatic and lung cancer, but no medicines that target RAS are available despite decades of effort.

12 Jan 2018

People with family history of heart attack may be more at risk

The president of the American Heart Association, Dr John Warner, had a minor heart attack recently during a scientific conference held in California.

12 Jan 2018

Research provides insights into mechanisms governing healthy longevity

Keio University Global Research Institute, Tokyo publishes the January 2018 issue of KGRI Research Frontiers that includes researcher video profiles of Keio University researchers and research highlights from high impact publications including 'Regenerative medicine needs collaboration in and out of science in order to face current and future challenges; ‘Does eating fish protect you from depression?’; ‘Insights into the molecular mechanisms leading to kidney dysfunction in diabetic patients’; and ‘Ageing to 100 and beyond: Insights from demographic, phenotypic and genetic studies.

12 Jan 2018

New analysis highlights need for protective therapy to reduce risk of repeat heart attacks

AstraZeneca announced today the publication of a new analysis from an ongoing real-world quality registry that suggests the risk of experiencing a repeat heart attack (also known as a myocardial infarction or MI) from occlusions in non-stented arteries is twice as high as the risk stemming from the initially stented artery following a first heart attack.

12 Jan 2018

Mount Sinai study uncovers potential link between Crohn's and Parkinson's in Jewish population

Mount Sinai Researchers have just discovered that patients in the Ashkenazi Jewish population with Crohn's disease (a chronic inflammatory of the digestive system) are more likely to carry the LRRK2 gene mutation.

11 Jan 2018

New study shows how the immune system regulates gut fungal population

Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists.

11 Jan 2018

UPM researchers successfully simulate real-time migraine prediction system

UPM researchers, in collaboration with UCM and Hospital Universitario de la Princesa, have successfully simulated a system that alert patients to an incoming migraine crisis in real time. According to the simulation results, the reliability of this system is over 75%.

11 Jan 2018

Computer model based on AI improves analysis of kidney biopsies

The ability to quantify the extent of kidney damage and predict the life remaining in the kidney, using an image obtained at the time when a patient visits the hospital for a kidney biopsy, now is possible using a computer model based on artificial intelligence.

11 Jan 2018

CAP releases new guideline for HPV testing in patients with head and neck cancers

Certain head and neck cancers that are positive for high-risk types of human papillomavirus (HPV) have a better prognosis and may need less aggressive treatment.

11 Jan 2018