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UC researchers advocate ‘precision medicine’ approach to studying and treating Parkinson's disease

Two landmark publications with one or more co-authors from the University of Cincinnati Gardner Neuroscience Institute outline a transformative approach to defining, studying and treating Parkinson's disease.

22 Mar 2017

Heroin use linked to epigenetic alterations in the brain

Heroin use is associated with excessive histone acetylation, an epigenetic process that regulates gene expression, and more years of drug use correlate with higher levels of hyperacetylation, according to research conducted at The Icahn School of Medicine at Mount Sinai and published in the journal Biological Psychiatry.

22 Mar 2017

Machine learning helps researchers uncover cellular control networks

The flow of information between cells in our bodies is exceedingly complex: sensing, signaling, and influencing each other in a constant flow of microscopic engagements. These interactions are critical for life, and when they go awry can lead to the illness and injury.

22 Mar 2017

Study shows safety of Schwann cell transplantation for treating subacute thoracic spinal cord injury

A Phase I clinical trial that targeted individuals with new onset paraplegia to evaluate the safety of transplanting their own potentially neuroprotective Schwann cells into a trauma-induced spinal cord lesion showed no evidence of adverse effects after 1 year.

22 Mar 2017

Researchers find new way to expand, preserve cord-blood cells as potential treatment for Type 1 diabetes

For parents, storing their newborn baby's umbilical cord blood is a way to preserve potentially lifesaving cells. Now, a group of University of Florida Health researchers has found a way to expand and preserve certain cord-blood cells as a potential treatment for Type 1 diabetes.

22 Mar 2017

Study: Unsaturated fatty acid metabolism associated with progression of Alzheimer's disease

A new study published in PLOS Medicine's Special Issue on Dementia has found that the metabolism of omega-3 and omega-6 unsaturated fatty acids in the brain are associated with the progression of Alzheimer's disease.

22 Mar 2017

New study challenges description of airway inflammation in smokers and COPD patients

A new study challenges the widely accepted but oversimplified description of airway inflammation in smokers and patients with chronic obstructive pulmonary disease (COPD).

22 Mar 2017

New review addresses mysteries behind ‘good’ HDL cholesterol metabolism

A new review addresses the mysteries behind "good" HDL cholesterol and why boosting its levels does not necessarily provide protection from cardiovascular risk for patients. It appears that augmenting the function of HDL cholesterol, rather than its concentration, is key.

22 Mar 2017

Study finds increased heart attack risk in patients taking direct acting oral anticoagulants

A new study has examined whether different blood thinning medications prescribed to prevent strokes in patients with atrial fibrillation might increase the risk of heart attacks.

22 Mar 2017

Many adults have poor knowledge about severity and prognosis of heart failure

In the largest German survey on heart failure to date, investigators found that the overall awareness of heart failure has not increased over the past decade and is not at a satisfactory level.

22 Mar 2017

'Cannibal drug' consumption in adolescence can increase vulnerability to cocaine use during adulthood

Consumption of the synthetic drug MDPV -a powerful psychostimulant known as 'cannibal drug'- in adolescence, can increase vulnerability of cocaine addiction during adulthood, according to a study carried out with laboratory animals and led by the researchers Elena Escubedo, from the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine of the UB and Olga Valverde, head of the Neurobiology of Behaviour Research Group of Pompeu Fabra University.

22 Mar 2017

Study shows efficacy of biologics for mucosal healing in Crohn's disease and ulcerative colitis

Although anti-inflammatory treatments are quite effective at reducing symptoms in patients with Crohn's disease and ulcerative colitis, the mucosal lining of the intestine often remains ulcerated, and many patients still ultimately require surgery.

22 Mar 2017

SPECT imaging may not be suitable for monitoring Parkinson's disease, study shows

When monitoring Parkinson's disease, SPECT imaging of the brain is used for acquiring information on the dopamine activity. A new study conducted in Turku, Finland, shows that the dopamine activity observed in SPECT imaging does not reflect the number of dopamine neurons in the substantia nigra, as previously assumed.

22 Mar 2017

Poor smell linked to higher risk of early mortality

In a study of adults aged 40 to 90 years who were followed for 10 years, poor smell was linked with an increased risk of dying.

22 Mar 2017

Philips announces results from clinical studies comparing iFR- and FFR-guided strategy for assessment of heart disease

Royal Philips today announced that the results from two large clinical trials comparing patient outcomes using instant wave-free ratio (iFR) and fractional flow reserve (FFR) in the diagnosis and treatment of heart disease have been published in the New England Journal of Medicine.

From Philips Healthcare 22 Mar 2017

New recommendations aim to guide doctors and patients about testing, treatment options

Surgical options for people with medical conditions including obesity, and the risks of operating on the elderly, feature among 10 new recommendations released today under the Choosing Wisely Australia initiative.

22 Mar 2017

Study to assess effectiveness of two OTC medications for treating alcoholism in bipolar patients

Researchers have long wondered if medications could treat alcohol abuse. Ihsan Salloum, M.D., chief of the Division of Alcohol and Drug Abuse at the University of Miami Miller School of Medicine, hopes to answer that question in part with a new clinical trial with E. Sherwood Brown, M.D., Ph.D., at UT Southwestern Medical Center in Dallas.

22 Mar 2017

Changes in the vascular system could play role in initiating Alzheimer’s disease

As the average age of Americans increases, so too does the problem of Alzheimer's, one of the world's most common neurological diseases. In recent years, scientists have explored many new approaches to clear the plaques and tangles in the brain that characterize the condition, but the new drugs have largely turned out to be disappointing.

22 Mar 2017

Dana-Farber and Lifespan enter into strategic alliance to advance cancer treatment and research

Dana-Farber Cancer Institute and Lifespan leadership are creating a strategic alliance to advance cancer treatment and research.

22 Mar 2017

ARVO urges Congress to reject budget proposal that seeks to cut NIH funding

The Association for Research in Vision and Ophthalmology urges Congressional leaders to reject the U.S. administration's recent FY18 budget proposal, which seeks to drastically cut National Institute of Health funding by nearly $6 billion, or 20%.

22 Mar 2017

Medical Condition News

UC researchers advocate ‘precision medicine’ approach to studying and treating Parkinson's disease

Heroin use linked to epigenetic alterations in the brain

Machine learning helps researchers uncover cellular control networks

Study shows safety of Schwann cell transplantation for treating subacute thoracic spinal cord injury

Researchers find new way to expand, preserve cord-blood cells as potential treatment for Type 1 diabetes

Study: Unsaturated fatty acid metabolism associated with progression of Alzheimer's disease

New study challenges description of airway inflammation in smokers and COPD patients

New review addresses mysteries behind ‘good’ HDL cholesterol metabolism

Study finds increased heart attack risk in patients taking direct acting oral anticoagulants

Many adults have poor knowledge about severity and prognosis of heart failure

'Cannibal drug' consumption in adolescence can increase vulnerability to cocaine use during adulthood

Study shows efficacy of biologics for mucosal healing in Crohn's disease and ulcerative colitis

SPECT imaging may not be suitable for monitoring Parkinson's disease, study shows

Poor smell linked to higher risk of early mortality

Philips announces results from clinical studies comparing iFR- and FFR-guided strategy for assessment of heart disease

New recommendations aim to guide doctors and patients about testing, treatment options

Study to assess effectiveness of two OTC medications for treating alcoholism in bipolar patients

Changes in the vascular system could play role in initiating Alzheimer’s disease

Dana-Farber and Lifespan enter into strategic alliance to advance cancer treatment and research

ARVO urges Congress to reject budget proposal that seeks to cut NIH funding

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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