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Unlocking the first gene to cause otosclerosis: an interview with Dr Ralph Holme

Otosclerosis is a common cause of hearing loss, particularly amongst young adults. It normally starts in their 20s or 30s and it affects about 1 in 200 hundred people. In the UK, about 300,000 people are affected by the condition.

7 Jun 2016

Innovative mouse model could provide new strategy to arrest growth of pancreatic cancer

Pancreatic ductal adenocarcinoma, the most common of pancreatic cancers, is extraordinarily lethal, with a 5-year survival rate of just 6 percent. Chemotherapy treatments are poorly effective, in part due to a high degree of drug-resistance to currently used regimens.

7 Jun 2016

HKUST study suggests innate immune response plays vital role in pathogenesis of AD

Alzheimer's disease (AD) is a devastating condition with no known effective treatment. The disease is characterized by memory loss as well as impaired locomotor ability, reasoning, and judgment. Emerging evidence suggests that the innate immune response plays a major role in the pathogenesis of AD.

7 Jun 2016

Loughborough research reveals most effective way of boosting muscle strength

Engaging in short, explosive leg contractions is the most effective way of strengthening muscles, Loughborough research reveals.

7 Jun 2016

Researchers find increased cancer incidence among patients with primary immunodeficiency disorders

Primary immunodeficiency disorders are a group of more than 300 single gene defects that affect the role of the immune system and prevent it from functioning properly. When Roswell Park Cancer Institute researchers evaluated the overall and site-specific incidence of cancer among patients registered in the United States Immune Deficiency Network, they found increased cancer incidence rates among patients with primary immunodeficiency diseases — and, in particular, a significant increase in lymphoma cases.

7 Jun 2016

Epigenomic alterations play key role in triggering obesity-induced diabetes

Obesity is a risk factor for developing type 2 diabetes, yet not all obese humans develop the disease. In a new study, researchers from the Karolinska Institutet in Sweden and from the Institute of Health and Medical Research in France have identified epigenomic alterations that are associated with inflammation and type 2 diabetes

7 Jun 2016

Genes of healthy leanness could lead to new approach to treating obesity-related diabetes

People with type 2 diabetes could be helped by the discovery of a gene linked to leanness.

7 Jun 2016

Northwestern Medicine scientists link TMEM230 gene mutations to Parkinson's disease development

Northwestern Medicine scientists have discovered a new cause of Parkinson's disease -- mutations in a gene called TMEM230. This appears to be the third gene definitively linked to confirmed cases of the common movement disorder.

7 Jun 2016

Spider venom helps investigate pain signals experienced by irritable bowel syndrome patients

Spiders have helped researchers from Australia and the US discover a new target for irritable bowel syndrome pain.

7 Jun 2016

Antiinflammatory drug HUMIRA enhances specific TNF function in rheumatoid arthritis patients

Researchers from University College London have discovered that the widely used antiinflammatory drug HUMIRA doesn't just work by inhibiting its target protein, TNF, but by enhancing a particular function of TNF in rheumatoid arthritis patients.

7 Jun 2016

Researchers aim to find new approach to improve chronic wound repair

Chronic wounds cause nearly 80,000 lower leg amputations annually in the U.S. alone and are associated with an increased likelihood of death.

6 Jun 2016

Financial pressures prevent access to much-needed care for cancer patients

Financial pressures kept cancer patients from filling prescription medications and attending their doctors' visits, University of North Carolina Lineberger Comprehensive Cancer Center researchers found in a new study.

6 Jun 2016

Clinical study shows improved outcomes for NET patients treated with Lutathera over Octreotide LAR

NETTER-1 study, showing clinically meaningful and significant results for Lutathera (77Lu-DOTA0-Tyr3-Octreotate) in patients with metastatic midgut neuroendocrine tumors (NETs). The data will be presented Monday, June 6, during the American Society of Clinical Oncology Annual Meeting in Chicago.

6 Jun 2016

Scientists use X-rays to study how eculizumab prevents immune system from damaging kidney tissue

In collaboration with Alexion Pharmaceuticals, Inc., scientists from Aarhus University have used X-rays to understand how the therapeutic antibody eculizumab prevents our immune system from destroying red blood cells and damaging kidney tissue.

6 Jun 2016

Advances in precision diagnostics aid accurate detection of CNS tumors

Thanks to new methods of precision diagnostics, such as DNA sequencing and epigenetic analyses, it is becoming increasingly possible to identify specific central nervous system (CNS) tumors accurately and to provide targeted treatment. The Comprehensive Cancer Center of MedUni Vienna and Vienna General Hospital is one of the top centers in the world for diagnosing and treating this type of tumor.

6 Jun 2016

Personlized exercise pattern may help reduce neuropathic symptoms of chemotherapy

Researchers at the University of Rochester Wilmot Cancer Institute discovered something simple and inexpensive to reduce neuropathy in hands and feet due to chemotherapy--exercise.

6 Jun 2016

IQWiG examines whether ramucirumab drug offers added benefit for MCRC and NSCLC patients

Ramucirumab is a monoclonal antibody, which blocks a receptor, reducing the growth of blood vessels and so reducing blood supply to the tumours.

6 Jun 2016

Study finds no added benefit of empagliflozin alone or in combination for type 2 diabetes

Empagliflozin has been approved since May 2014 for adults with type 2 diabetes mellitus in whom diet and exercise alone do not provide adequate glycaemic control.

6 Jun 2016

Delivering genetic test results over the phone may help ease cost, burden for at-risk cancer patients

Delivering genetic test results to patients at risk for cancer-causing genetic mutations over the phone helps to ease cost and transportation burdens and, compared to receiving results in person, does not cause patients additional stress, according to a new study from the Abramson Cancer Center of the University of Pennsylvania which will be presented at the American Society of Clinical Oncology Annual Meeting.

6 Jun 2016

Study offers more insights into how sensory experiences shape brain development

Most people encounter most things by sensing them in multiple ways. As we hear the words people speak, we also see their lips move. We smell, see and hear the onions as we chop them -- and we feel them with teary eyes.

6 Jun 2016

Medical Condition News

Unlocking the first gene to cause otosclerosis: an interview with Dr Ralph Holme

Innovative mouse model could provide new strategy to arrest growth of pancreatic cancer

HKUST study suggests innate immune response plays vital role in pathogenesis of AD

Loughborough research reveals most effective way of boosting muscle strength

Researchers find increased cancer incidence among patients with primary immunodeficiency disorders

Epigenomic alterations play key role in triggering obesity-induced diabetes

Genes of healthy leanness could lead to new approach to treating obesity-related diabetes

Northwestern Medicine scientists link TMEM230 gene mutations to Parkinson's disease development

Spider venom helps investigate pain signals experienced by irritable bowel syndrome patients

Antiinflammatory drug HUMIRA enhances specific TNF function in rheumatoid arthritis patients

Researchers aim to find new approach to improve chronic wound repair

Financial pressures prevent access to much-needed care for cancer patients

Clinical study shows improved outcomes for NET patients treated with Lutathera over Octreotide LAR

Scientists use X-rays to study how eculizumab prevents immune system from damaging kidney tissue

Advances in precision diagnostics aid accurate detection of CNS tumors

Personlized exercise pattern may help reduce neuropathic symptoms of chemotherapy

IQWiG examines whether ramucirumab drug offers added benefit for MCRC and NSCLC patients

Study finds no added benefit of empagliflozin alone or in combination for type 2 diabetes

Delivering genetic test results over the phone may help ease cost, burden for at-risk cancer patients

Study offers more insights into how sensory experiences shape brain development

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

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