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Cobimetinib combined with vemurafenib shows added benefit for melanoma with BRAF V600 mutation

Cobimetinib has been approved since November 2015 in combination with vemurafenib for the treatment of adults with advanced, i.e. metastatic or unresectable, melanoma with a BRAF V600 mutation.

6 Jun 2016

New study finds alternative approaches to target proteins sustaining cancer, Alzheimer's disease

Drugs to treat cancer and Alzheimer's disease usually target the active sites of specific protein molecules sustaining the disease. Traditional drug design views proteins as rigid 3-D objects with active sites consisting of surface-accessible "pockets" with a specific, well-defined structure.

6 Jun 2016

Rare DNA alteration may increase rsk of multiple sclerosis

Scientists at the University of British Columbia and Vancouver Coastal Health have proven that multiple sclerosis (MS) can be caused by a single genetic mutation - a rare alteration in DNA that makes it very likely a person will develop the more devastating form of the neurological disease.

6 Jun 2016

Giving chemotherapy after radiotherapy delays rare brain tumour growth

GIVING chemotherapy after radiotherapy delays further growth of a rare type of brain tumour, increasing the number of patients alive at five years from 44 per cent to 56 per cent.

6 Jun 2016

Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients

Researchers at the University of Cincinnati College of Medicine have found that adding increasing doses of an approved Type 2 diabetes drug, metformin, to a chemotherapy and radiation treatment regimen in head and neck cancer patients is not well tolerated if escalated too quickly, but allowing slower escalation could be beneficial.

6 Jun 2016

Study finds link between stress hormone and stage of schizophrenia

JCU Associate Professor Zoltan Sarnyai said it was the first meta-analysis study to compare the level of cortisol in a waking patient's body with the stage of schizophrenia they are suffering.

6 Jun 2016

Joint research reveals key mechanisms of persistent latent infection of HTLV-1

Joint research between scientists from Kumamoto University, Japan and Imperial College London, UK has revealed the mechanisms of persistent latent infection of the human T-cell leukemia virus type 1 (HTLV-1).

6 Jun 2016

Radiation therapy with bevacizumab/pembrolizumab improves outcomes in glioma patients

Patients with recurrent high-grade glioma brain tumors have few effective treatment options and the majority of available therapies do not improve survival. Moffitt Cancer Center will present preliminary results from a phase 1 study testing whether the addition of pembrolizumab to radiation therapy and bevacizumab is safe and can control tumor growth for these patients.

6 Jun 2016

Targeted therapy rucaparib shows promise in treating pancreatic cancer patients with BRCA mutation

The targeted therapy rucaparib, which has demonstrated robust clinical activity in ovarian cancer patients with a BRCA mutation, also showed promise in previously treated pancreatic cancer patients with the mutation, according to results from a phase II clinical study presented by Susan M. Domchek, MD, executive director of the Basser Center for BRCA at the Abramson Cancer Center of the University of Pennsylvania, at the American Society of Clinical Oncology Annual Meeting.

6 Jun 2016

Autoimmune diseases among lung cancer patients may make them unsuitable for immunotherapy

A significant proportion of lung cancer patients also have autoimmune disease, which may make them unsuitable for increasingly popular immunotherapy treatments, a team of researchers at UT Southwestern Medical Center's Harold C. Simmons Comprehensive Cancer Center has found.

6 Jun 2016

Gene dysregulation makes immune therapies less effective against metastatic melanoma

Patients who don't respond to treatments that use their own immune cells to destroy tumors, called tumor infiltrating lymphocytes, share changes in mechanisms that switch genes on or off in those cells, according to study results presented at the annual meeting of the American Society for Clinical Oncology on June 4 in Chicago.

6 Jun 2016

Colorectal cancer significantly increasing among younger adults, shows study

The National Comprehensive Cancer Network recommends that colorectal cancer (CRC) screening begin at age 50. This means that less is known about the occurrence of the disease in people under age 50.

6 Jun 2016

Combination therapy equally good at treating small cell lung cancer

HAVING radiotherapy once a day for six and a half weeks or twice a day for three weeks -- when combined with chemotherapy -- is equally good at treating small cell lung cancer that hasn't spread.

6 Jun 2016

MBC Project engages patients directly to accelerate cancer research

A crowd-sourcing strategy aimed at accelerating research into metastatic breast cancer has connected advocacy groups, social media, and a dedicated web site to register more than 2,000 patients from all 50 states in its first seven months, say researchers from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

6 Jun 2016

Study finds increased risk of mortality in black, Hispanic cancer patients

Hispanic white and non-Hispanic black cancer patients between ages 15 and 29 may be more likely than same-aged white patients to die of their disease, according to a University of Colorado Cancer Center study presented at the American Society for Clinical Oncology Annual Meeting 2016.

6 Jun 2016

Maintenance lenalidomide treatment improves overall survival in multiple myeloma patients

While several clinical trials have demonstrated that maintenance therapy with lenalidomide reduces the risk of disease progression in patients with multiple myeloma, there have been no definitive results regarding overall survival.

6 Jun 2016

Gene alterations in WNT pathway may increase CRC risk in younger patients

While increased screening continues to drive down overall colorectal cancer rates, the rate of colorectal cancer in patients under age 50 is increasing, and the disease is commonly more aggressive in these young patients.

6 Jun 2016

Novel drug atezolizumab harnesses immune system to shrink tumors in advanced bladder cancer

A new drug that harnesses the immune system to attack tumors is highly effective against advanced bladder cancer, according to the results of an international clinical trial to be presented June 5 at the annual meeting of the American Society for Clinical Oncology.

6 Jun 2016

Experimental drug Rova-T shows safety, efficacy in treating advanced SCLC patients

The experimental "smart-bomb" drug rovalpituzumab tesirine (Rova-T) appears safe and shows efficacy in treating patients with advanced small cell lung cancer (SCLC), according to results from a first-in-human clinical trial to be presented today by a Memorial Sloan Kettering Cancer Center researcher at the 2016 American Society of Clinical Oncology Annual Meeting in Chicago.

6 Jun 2016

Nivolumab drug shows better response rate in metastatic bladder cancer patients

The immune checkpoint blockade drug nivolumab reduced tumor burden in 24.4 percent of patients with metastatic bladder cancer, regardless of whether their tumors had a biomarker related to the drug's target, according to clinical trial results from The University of Texas MD Anderson Cancer Center.

6 Jun 2016

Medical Condition News

Cobimetinib combined with vemurafenib shows added benefit for melanoma with BRAF V600 mutation

New study finds alternative approaches to target proteins sustaining cancer, Alzheimer's disease

Rare DNA alteration may increase rsk of multiple sclerosis

Giving chemotherapy after radiotherapy delays rare brain tumour growth

Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients

Study finds link between stress hormone and stage of schizophrenia

Joint research reveals key mechanisms of persistent latent infection of HTLV-1

Radiation therapy with bevacizumab/pembrolizumab improves outcomes in glioma patients

Targeted therapy rucaparib shows promise in treating pancreatic cancer patients with BRCA mutation

Autoimmune diseases among lung cancer patients may make them unsuitable for immunotherapy

Gene dysregulation makes immune therapies less effective against metastatic melanoma

Colorectal cancer significantly increasing among younger adults, shows study

Combination therapy equally good at treating small cell lung cancer

MBC Project engages patients directly to accelerate cancer research

Study finds increased risk of mortality in black, Hispanic cancer patients

Maintenance lenalidomide treatment improves overall survival in multiple myeloma patients

Gene alterations in WNT pathway may increase CRC risk in younger patients

Novel drug atezolizumab harnesses immune system to shrink tumors in advanced bladder cancer

Experimental drug Rova-T shows safety, efficacy in treating advanced SCLC patients

Nivolumab drug shows better response rate in metastatic bladder cancer patients

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

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