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New research reveals underlying biomechanics involved in meniscus fibrocartilage function

Knee injuries are among the top five reasons people visit an orthopedic surgeon for treatments, which include 719,000 total knee replacements performed annually in the United States. Now, new research reveals underlying biomechanics that may be involved in meniscus fibrocartilage function as well as dysfunction and could guide novel treatments for some of the most debilitating and costly orthopedic problems in the U.S., including meniscus tears and age-related joint degeneration.

22 Feb 2016

Researchers analyze how Topo II enzyme may affect stability of genomes

While researchers are now familiar with how cancer begins—cells mutate and then multiply wildly out of control—it is still uncertain exactly how that mutation starts in the molecules of the cells.

22 Feb 2016

Newly developed intravital microscopy system proves safe for use in humans

A team of Roswell Park Cancer Institute researchers has developed and evaluated the first intravital microscopy system shown to be safe for use in humans. Writing in the journal Nature Communications, the scientists report that their proprietary technology enabled them, for the first time ever, to visualize tumor blood vessels in real time.

22 Feb 2016

UCL researchers create first massive open online course on four less-common forms of dementia

Researchers at University College London have created the first massive open online course on four of the less-common forms of dementia. Developed by Timothy Shakespeare, with Sebastian Crutch and Nick Fox, "The Many Faces of Dementia" will kick off on March 14.

22 Feb 2016

Masked hypertension linked with increased risks of kidney, heart and vascular damage

Many patients with chronic kidney disease (CKD) have hypertension that is not detected in the clinic, and such 'masked' hypertension is linked with increased risks of kidney, heart, and vascular damage.

22 Feb 2016

Stenting and surgery equally effective at lowering long-term risk of stroke

Investigators for the Carotid Revascularization Endarterectomy versus Stenting Trial found that stenting and surgery are equally effective at lowering the long-term risk of stroke from a narrowed carotid artery, according to a study published today in The New England Journal of Medicine.

22 Feb 2016

Scientists resolve tumor heterogeneity using innovative DEPArray technology

Using the innovative DEPArray technology, scientists at Silicon Biosystems, a Bologna (Italy) and San Diego (CA, USA) based biotech company, were able to solve one of the biggest limitation in the study of cancer genetic: tumor samples heterogeneity.

22 Feb 2016

Berlin researchers use T cells to target mutations in cancer cells

The efficacy of the immune system to combat disease makes the body's own healing powers a promising approach in the fight against cancer. A Berlin research group led by Wolfgang Uckert, Thomas Blankenstein and Matthias Leisegang has been collaborating with U.S. researcher Hans Schreiber in a project to use immune components called T cells to target mutant proteins produced by cancer cells.

22 Feb 2016

New findings on gut microbiota to be discussed at 2016 Gut Microbiota for Health World Summit

Novel approaches for manipulating the gut microbiota through diet, pre- and probiotics, targeted antibiotic therapy and fecal microbiota transplantation for health maintenance and treatment are under investigation or already in use.

22 Feb 2016

Dr. Elliot J. Androphy receives IGNITE grant to develop drug candidate for spinal muscular atrophy

Dr. Elliot J. Androphy, the Kampen-Norins Professor and chair of the Department of Dermatology at the Indiana University School of Medicine, has been awarded an IGNITE, or Innovation Grants to Nurture Initial Translational Efforts, grant by the National Institutes of Health.

22 Feb 2016

New molecular delivery system could help ensure delivery of chemotherapy drugs into tumours

Chemotherapy isn't supposed to make your hair fall out -- it's supposed to kill cancer cells. A new molecular delivery system created at U of T Engineering could help ensure that chemotherapy drugs get to their target while minimizing collateral damage.

22 Feb 2016

Australian researchers reveal how nutlins pave way for improving future of cancer treatment

Australian researchers have resolved a mystery about how a promising new class of anti-cancer drugs, called nutlins, work - paving the way for improving the future of cancer treatment.

22 Feb 2016

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer's disease and improvements in monitoring the effects of medication.

22 Feb 2016

Scientists find that lifespan of supportive cells in tumor may control cancer metastasis

Researchers have discovered that eliminating cells thought to aid tumor growth did not slow or halt the growth of cancer tumors. In fact, when the cancer-associated fibroblasts (CAFs), were eliminated after 10 days, the risk of metastasis of the primary tumor to the lungs and bones of mice increased dramatically.

22 Feb 2016

New article describes recent efforts made by researchers to classify bladder cancers

The ability to map the human genome has transformed how scientists and researchers classify various cancers. In the past, cancer cells were examined through a microscope and their appearance, often enhanced with dyes or other agents, was used to categorize the type of cancer.

22 Feb 2016

New study focuses on safety of using induced pluripotent stem cells in patients

A new study led by scientists at The Scripps Research Institute and the J. Craig Venter Institute shows that the act of creating pluripotent stem cells for clinical use is unlikely to pass on cancer-causing mutations to patients.

22 Feb 2016

New discoveries provide further evidence for benefits of a good night's sleep

Why does sleeping on it help? This is the question tackled by new research at the University of Bristol, which reveals how brain activity during sleep sorts through the huge number of experiences we encounter every day, filing only the important information in memory.

22 Feb 2016

Researchers identify common molecular alteration in glioblastoma

Glioblastoma is the most aggressive manifestation of brain tumours. Due to its high invasive capacity and uncontrolled, infiltrating growth, it is particularly difficult to manage. Currently, the treatment for this disease consists of a combination of surgery (when possible), radiation and chemotherapy.

22 Feb 2016

Air pollution exposure increases obesity risk

Laboratory rats who breathed Beijing's highly polluted air gained weight and experienced cardio-respiratory and metabolic dysfunctions after three to eight weeks of exposure.

22 Feb 2016

Mylan announces FDA's acceptance of ANDA filing for generic Advair Diskus

Mylan N.V. today announced that its abbreviated new drug application (ANDA) for fluticasone propionate 100, 250, 500 mcg and salmeterol 50 mcg inhalation powder has been accepted for filing by the U.S. Food and Drug Administration.

22 Feb 2016

Medical Condition News

New research reveals underlying biomechanics involved in meniscus fibrocartilage function

Researchers analyze how Topo II enzyme may affect stability of genomes

Newly developed intravital microscopy system proves safe for use in humans

UCL researchers create first massive open online course on four less-common forms of dementia

Masked hypertension linked with increased risks of kidney, heart and vascular damage

Stenting and surgery equally effective at lowering long-term risk of stroke

Scientists resolve tumor heterogeneity using innovative DEPArray technology

Berlin researchers use T cells to target mutations in cancer cells

New findings on gut microbiota to be discussed at 2016 Gut Microbiota for Health World Summit

Dr. Elliot J. Androphy receives IGNITE grant to develop drug candidate for spinal muscular atrophy

New molecular delivery system could help ensure delivery of chemotherapy drugs into tumours

Australian researchers reveal how nutlins pave way for improving future of cancer treatment

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

Scientists find that lifespan of supportive cells in tumor may control cancer metastasis

New article describes recent efforts made by researchers to classify bladder cancers

New study focuses on safety of using induced pluripotent stem cells in patients

New discoveries provide further evidence for benefits of a good night's sleep

Researchers identify common molecular alteration in glioblastoma

Air pollution exposure increases obesity risk

Mylan announces FDA's acceptance of ANDA filing for generic Advair Diskus

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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