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GeNeuro initiates GNbAC1 Phase IIb study in Relapsing-Remitting Multiple Sclerosis

GeNeuro SA, a pioneer of new therapies for neurology and autoimmune disorders, announced today that it has initiated its planned Phase IIb study “CHANGE-MS” (Clinical trial assessing the HERV-W Env ANtagonist GNbAC1 for Efficacy in Multiple Sclerosis) with its lead antibody GNbAC1 in Relapsing-Remitting Multiple Sclerosis (RRMS).

21 Dec 2015

Adaptimmune begins Phase I/II study of affinity enhanced T-cell therapy targeting MAGE-A10 in NSCLC patients

Adaptimmune Therapeutics plc, a leader in the use of TCR engineered T-cell therapy to treat cancer, today announced that it has initiated a Phase I/II study of its affinity enhanced T-cell therapy targeting the MAGE-A10 cancer antigen in patients with locally advanced or metastatic (Stage IIIb or IV) non-small cell lung cancer (NSCLC), the most prevalent type of lung cancer representing approximately 85 percent of lung cancers.

21 Dec 2015

Protective effects of high fitness against early death reduced in obese people, study finds

A new study, published today in the International Journal of Epidemiology, has dismissed the concept of 'fat but fit'. In contrast, the results from the new study suggest that the protective effects of high fitness against early death are reduced in obese people.

20 Dec 2015

Endoscopic submucosal dissection appears to be effective treatment for patients with throat cancer

According to a study in the December issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy, endoscopic submucosal dissection (ESD) appears to be a safe and effective minimally invasive treatment for patients with superficial pharyngeal (throat) cancer.

20 Dec 2015

USC-led study finds link between anxiety and dementia

People who experienced high anxiety any time in their lives had a 48 percent higher risk of developing dementia compared to those who had not, according to a new study led by USC researchers.

20 Dec 2015

Teens with moderate mental health problems vape e-cigarettes

Teenagers with moderate mental health problems who may not have considered smoking conventional cigarettes are turning to electronic cigarettes, a new USC study has found.

20 Dec 2015

Variant signs worldwide exclusive license and development agreement with L&F Research

Variant Pharmaceuticals, Inc., an emerging pharmaceutical company focusing on rare diseases and other specialty conditions with limited or sub-optimal therapeutic options, announced today a worldwide exclusive license and development agreement with L&F Research LLC to advance development of Variant's lead product, VAR 200.

20 Dec 2015

FDA approves Fenix Continence Restoration System to treat fecal incontinence

The U.S. Food and Drug Administration today approved the Fenix Continence Restoration System to treat fecal incontinence in patients who are not candidates for, or have previously failed, medical or other surgical options.

20 Dec 2015

DS Biopharma reports completion of DS102 Phase I trial for treatment of fatty liver disorders

DS Biopharma, a privately held biopharmaceutical company, today announced the successful completion of a Phase I trial with an oral formulation of the active pharmaceutical ingredient DS102 (15-HEPE) which is being explored for the treatment of fatty liver disorders, such as non-alcoholic steatohepatitis (NASH) and pulmonary disorders, such as idiopathic pulmonary fibrosis (IPF).

18 Dec 2015

UCLA study may help resolve a neurological mystery

UCLA researchers have found that space-mapping neurons - the GPS system in the brain - have a strong dependence on what is being looked at when triangulating location, a finding that resolves a neurological mystery that has vexed scientists for more than four decades.

18 Dec 2015

UT Southwestern study to evaluate new protocols designed to treat stroke patients using telemedicine

A UT Southwestern Medical Center study to evaluate nursing protocols designed to better triage and treat stroke patients using telemedicine will be the first study using a new consortium of medical centers.

18 Dec 2015

Chronic alcohol use with repeated binge drinking can cause more damage to the liver

Excessive alcohol consumption is a global public health issue. In the United States, binge drinking is the most common form - so common, in fact, that the Centers for Disease Control and Prevention reports approximately one in six adults binge drinks about four times each month.

18 Dec 2015

Synthetic biomaterial aids in regeneration of skin cells to improve wound healing

Some skin wounds, such as diabetic ulcers, are chronic and may never heal; others, such as burn wounds, are often large and difficult to treat, resulting in pain, infection and scarring. Researchers at the University of California, Los Angeles, funded by the National Institutes of Health, have developed a synthetic biomaterial that fills wounds and aids in regeneration of skin cells, which ultimately improves wound healing.

18 Dec 2015

UB study traces how enigmatic molecules help cancer self-destruct

You've probably never heard of "sphingolipids" before. But these curiously named organic compounds play a vital role in one of humanity's most well-known diseases: cancer.

18 Dec 2015

Kitov announces more data from Phase III trial on the favorable blood pressure effects of KIT-302

Kitov Pharmaceuticals, an innovative biopharmaceutical company focused on late-stage drug development, today announced more data from its successfully concluded Phase III trial for its lead drug candidate, KIT-302. Data showed the favorable blood pressure effects of KIT-302 were present in all blood pressure variables measured in the study.

18 Dec 2015

Chi-Med announces initiation of Phase III sulfatinib registration trial in patients with NETs in China

Hutchison China MediTech Limited today announces that Hutchison MediPharma Limited, its drug R&D subsidiary, has initiated SANET-ep, a Phase III sulfatinib (HMPL-012) registration trial in China in patients with extra-pancreatic neuroendocrine tumors ("NETs"), which are all non-pancreatic NETs, including, for example, NETs originating in the lymph, lung and across the gastrointestinal tract.

18 Dec 2015

New test can help detect cancer and diabetes biomarkers in bloodstream

A new test for detecting biomarkers for cancer and diabetes is more than 1000x more detailed and 100% faster than existing methods, new research by the University of Warwick suggests.

18 Dec 2015

New nanotechnology approach could transform gliomas from death sentence into treatable condition

An MRI contrast agent that can pass through the blood-brain barrier will allow doctors to detect deadly brain tumors called gliomas earlier, say Penn State College of Medicine researchers. This ability opens the door to make this fatal cancer treatable.

18 Dec 2015

Novel drug candidate prevents nerve cell damage in mouse model of Parkinson's disease

A team of scientists at the University of Nebraska Medical Center (UNMC) and Longevity Biotech, Inc., has demonstrated that neuroprotection could be attained in preclinical models by a novel drug candidate that changes immune responses.

18 Dec 2015

Presence of mirror in dining rooms can reduce perceived tastiness of unhealthy food

People often choose the unhealthy food because they think it is tastier. Aiming for solutions promoting healthy eating practices and ultimately combating obesity, this research shows that the presence of a mirror in a consumption setting can reduce the perceived tastiness of unhealthy food, which consequently reduces its consumption.

18 Dec 2015

Medical Condition News

GeNeuro initiates GNbAC1 Phase IIb study in Relapsing-Remitting Multiple Sclerosis

Adaptimmune begins Phase I/II study of affinity enhanced T-cell therapy targeting MAGE-A10 in NSCLC patients

Protective effects of high fitness against early death reduced in obese people, study finds

Endoscopic submucosal dissection appears to be effective treatment for patients with throat cancer

USC-led study finds link between anxiety and dementia

Teens with moderate mental health problems vape e-cigarettes

Variant signs worldwide exclusive license and development agreement with L&F Research

FDA approves Fenix Continence Restoration System to treat fecal incontinence

DS Biopharma reports completion of DS102 Phase I trial for treatment of fatty liver disorders

UCLA study may help resolve a neurological mystery

UT Southwestern study to evaluate new protocols designed to treat stroke patients using telemedicine

Chronic alcohol use with repeated binge drinking can cause more damage to the liver

Synthetic biomaterial aids in regeneration of skin cells to improve wound healing

UB study traces how enigmatic molecules help cancer self-destruct

Kitov announces more data from Phase III trial on the favorable blood pressure effects of KIT-302

Chi-Med announces initiation of Phase III sulfatinib registration trial in patients with NETs in China

New test can help detect cancer and diabetes biomarkers in bloodstream

New nanotechnology approach could transform gliomas from death sentence into treatable condition

Novel drug candidate prevents nerve cell damage in mouse model of Parkinson's disease

Presence of mirror in dining rooms can reduce perceived tastiness of unhealthy food

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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