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Researchers identify biochemical factors that may predict Alzheimer's disease

Investigators have wondered why the brains of some cognitively-intact elderly individuals have abundant pathology on autopsy or significant amyloid deposition on neuroimaging that are characteristic of Alzheimer disease (AD).

22 Dec 2015

QMUL, Barts Health NHS Trust receive £10.2m to create new cardiovascular academic medical centre

Queen Mary University of London and Barts Health NHS Trust have received £10.2m from Barts Charity for the creation of a world-class cardiovascular academic medical centre at the Trust's Barts Heart Centre, St Bartholomew's Hospital.

22 Dec 2015

Bern study sheds light on the brain mechanism of arousal

Scientists from Bern have discovered a mechanism which is responsible for the rapid arousal from sleep and anesthesia in the brain. The results of their study suggest new strategies for the medical treatment of sleep disorders and recovery of consciousness in vegetative states.

22 Dec 2015

Baxalta announces initial results from ADYNOVATE Phase 3 trial for treatment of hemophilia patients

Baxalta Incorporated, a global biopharmaceutical leader dedicated to delivering transformative therapies to patients with orphan diseases and underserved conditions, today announced initial results from a Phase 3 clinical trial of ADYNOVATE [Antihemophilic Factor (Recombinant), PEGylated], an extended circulating half-life recombinant Factor VIII (rFVIII) treatment for hemophilia A based on ADVATE [Antihemophilic Factor (Recombinant)].

22 Dec 2015

CSL submits rIX-FP new drug application to Japan's Pharmaceuticals and Medical Devices Agency

Global biotherapeutics leader CSL Behring announced today that the company has submitted its new drug application to Japan's Pharmaceuticals and Medical Devices Agency for its investigational fusion protein linking recombinant coagulation factor IX with recombinant albumin (rIX-FP).

22 Dec 2015

Large doses of vitamin A reduce severity of gastrointestinal disease in mice

After observing that some gastrointestinal disease in premature human and mouse infants progresses only when certain immune system white blood cells go into inflammatory overdrive, Johns Hopkins researchers have found that giving large doses of vitamin A to mice converts those blood cells into inflammation suppressors and reduces the severity of the disease, compared to untreated mice.

22 Dec 2015

Wnt5a protein acts on tumor-surface proteins to accelerate spread of CLL cells

Building upon previous research, scientists at University of California, San Diego School of Medicine and UC San Diego Moores Cancer report that a protein called Wnt5a acts on a pair of tumor-surface proteins, called ROR1 and ROR2, to accelerate the proliferation and spread of chronic lymphocytic leukemia (CLL) cells, the most common form of blood cancer in adults.

22 Dec 2015

Rutgers scientist provides insight into risks associated with using tanning bed

The U.S. Food and Drug Administration has proposed a ban on tanning bed use by those under 18. In 2013, a law was enacted in New Jersey banning those under the age of 17 from using tanning beds. Jerod L. Stapleton, PhD, is a behavioral scientist at Rutgers Cancer Institute of New Jersey and assistant professor of medicine at Rutgers Robert Wood Johnson Medical School, whose research aims to understand why young people frequently engage in indoor tanning.

22 Dec 2015

New treatment strategy may take pain away

A brain region controlling whether we feel happy or sad, as well as addiction, is remodeled by chronic pain, reports a new Northwestern Medicine study.

22 Dec 2015

New study examines single 'transformer' proteins involved in cancer

A new study led by scientists at The Scripps Research Institute and St. Jude Children's Research Hospital shows how a protein involved in cancer twists and morphs into different structures.

22 Dec 2015

Small price differences highly effective in shifting consumer demand to healthy low calorie alternatives

Small price differences at the point of purchase can be highly effective in shifting consumer demand from high calorie to healthier low calorie alternatives, according to a study in the Articles in Advance section of Marketing Science, a journal of the Institute for Operations Research and the Management Sciences.

22 Dec 2015

New MRI-based technology could help identify patients at risk of recurrent stroke

Patients who have had a stroke in the back of the brain are at greater risk of having another within two years if blood flow to the region is diminished, according to results of a multicenter study led by researchers at the University of Illinois at Chicago.

22 Dec 2015

Study reveals new genetic factors linked to age-related macular degeneration

An international study of about 43,000 people has significantly expanded the number of genetic factors known to play a role in age-related macular degeneration (AMD), a leading cause of vision loss among people age 50 and older.

22 Dec 2015

Scientists identify 52 genetic variations associated with age-related macular degeneration

In one of the latest examples of precision medicine, teams of geneticists from nine countries, involving more than 100 scientists, analyzed the genes of more than 33,000 individuals in the hope of finding genetic variations responsible for age-related macular degeneration (AMD), the leading cause of vision loss among people age 50 or older.

22 Dec 2015

Immunotherapy more effective than chemotherapy in treating patients with advanced lung cancer

A new study has found immunotherapy to be more effective than chemotherapy in treating most previously treated patients with advanced lung cancer, and demonstrated effectiveness in a wider population of people than previously known to benefit from the therapy.

22 Dec 2015

Drug that boosts activity in the brain's 'garbage disposal' system may slow Alzheimer's disease

A drug that boosts activity in the brain's "garbage disposal" system can decrease levels of toxic proteins associated with Alzheimer's disease and other neurodegenerative disorders and improve cognition in mice, a new study by neuroscientists at Columbia University Medical Center has found.

22 Dec 2015

Scientists identify genes linked to human intelligence

Scientists from Imperial College London have identified for the first time two clusters of genes linked to human intelligence.

22 Dec 2015

Patients treated at emergency departments for hypertension on the rise in US

The number and percentage of patients treated at emergency departments for hypertension are on the rise across the United States, according to a Vanderbilt University Medical Center study published recently in the American Journal of Cardiology.

22 Dec 2015

New drug approved by FDA for treatment of von Willebrand disease

"VONVENDI [von Willebrand factor (Recombinant)]", the new drug from Baxalta Incorporated, a global biopharmaceutical company recently spun off from Baxter International, has just been approved by the United States Food and Drug Administration.

22 Dec 2015

Benjamin Wolozin receives $500,000 award in Alzheimer's Disease Drug Discovery Research

Research that leads to improved therapies for Alzheimer's disease (AD) patients is one goal of Boston University School of Medicine professor of pharmacology and neurology Benjamin Wolozin, MD, PhD. He was one of six researchers awarded a two-year, $500,000 award in Alzheimer's Disease Drug Discovery Research by the Edward N. & Della L. Thome Memorial Foundation.

22 Dec 2015

Medical Condition News

Researchers identify biochemical factors that may predict Alzheimer's disease

QMUL, Barts Health NHS Trust receive £10.2m to create new cardiovascular academic medical centre

Bern study sheds light on the brain mechanism of arousal

Baxalta announces initial results from ADYNOVATE Phase 3 trial for treatment of hemophilia patients

CSL submits rIX-FP new drug application to Japan's Pharmaceuticals and Medical Devices Agency

Large doses of vitamin A reduce severity of gastrointestinal disease in mice

Wnt5a protein acts on tumor-surface proteins to accelerate spread of CLL cells

Rutgers scientist provides insight into risks associated with using tanning bed

New treatment strategy may take pain away

New study examines single 'transformer' proteins involved in cancer

Small price differences highly effective in shifting consumer demand to healthy low calorie alternatives

New MRI-based technology could help identify patients at risk of recurrent stroke

Study reveals new genetic factors linked to age-related macular degeneration

Scientists identify 52 genetic variations associated with age-related macular degeneration

Immunotherapy more effective than chemotherapy in treating patients with advanced lung cancer

Drug that boosts activity in the brain's 'garbage disposal' system may slow Alzheimer's disease

Scientists identify genes linked to human intelligence

Patients treated at emergency departments for hypertension on the rise in US

New drug approved by FDA for treatment of von Willebrand disease

Benjamin Wolozin receives $500,000 award in Alzheimer's Disease Drug Discovery Research

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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