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Scientists uncover novel strategy to block cancer's spread, restore tumor vulnerability to chemotherapy

St. Jude Children's Research Hospital scientists have discovered how an aggressive tumor of the muscle and soft tissue hijacks an export pathway in cells to lay the groundwork for cancer progression and resistance to chemotherapy.

22 Dec 2015

Small airway-on-a-chip enables analysis of human COPD and asthma

A research team at the Wyss Institute for Biologically Inspired Engineering at Harvard University leveraged its organ-on-a-chip technology to develop a model of the human small airway in which lung inflammatory diseases, such as chronic obstructive pulmonary disease (COPD), the third leading cause of mortality worldwide, and asthma can be studied outside the human body.

22 Dec 2015

Yale researchers reveal why chronic overeating tied to increased risk of depression

Chronic overeating and stress are tied to an increased risk of depression and anxiety, and in a new study, Yale researchers explain why that happens and suggest a possible solution.

22 Dec 2015

Study on myosins may lead to therapies for muscle diseases, cancers

Understanding how tiny molecular motors called myosins use energy to fuel biological tasks like contracting muscles could lead to therapies for muscle diseases and cancers, says a team of researchers led by Penn State College of Medicine scientists.

22 Dec 2015

Smokers who see graphic warning labels on cigarette packs have more negative feelings about smoking

A new study is the first to provide real-world evidence of the effectiveness of smoking warning labels that include graphic photos of the damage caused by regular tobacco use.

22 Dec 2015

Researchers outline novel molecular interactions affecting key cancer pathway in humans

Researchers from the Cancer Science Institute of Singapore at the National University of Singapore have delineated novel molecular interactions affecting the activity of the TGF-β pathway, a key cancer pathway in humans affecting cancer progression.

22 Dec 2015

Patients with EGFR-mutated lung cancer benefit more from afatinib as first-line treatment

Patients with EGFR-activating mutations in advanced lung cancer seem to benefit more from afatinib than gefitinib as first-line treatment, researchers report at the first ESMO Asia 2015 Congress in Singapore.

21 Dec 2015

Alexza reports interim results from AZ-002 Phase 2a study in epilepsy patients

Alexza Pharmaceuticals, Inc. today announced interim results of its Phase 2a study of AZ-002 (Staccato alprazolam) in epilepsy patients. AZ-002 produced a dose-related decrease in mean Standardized Photosensivity Range (SPR), the primary endpoint in the study.

21 Dec 2015

Many patients continue working after metastatic cancer diagnosis, study finds

A new analysis indicates that many patients continue working after being diagnosed with metastatic cancer, but a heavy burden of symptoms may prevent them from doing so. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study illustrates the need to treat difficult symptoms so that patients can maintain their employment.

21 Dec 2015

Nuvo Research announces topline results from WF10 Phase 2 trial for treatment of allergic rhinitis

Nuvo Research Inc., a life sciences company with growing revenues and a diverse portfolio of topical products, today announced the results of its investigational Phase 2 clinical trial of WF10 (Trial) for the treatment of allergic rhinitis.

21 Dec 2015

Bio Light's IOPtiMate system approved in Canada for treatment of glaucoma

Bio Light Israeli Life Sciences Investments Ltd., an emerging global ophthalmic company focused on the discovery, development and commercialization of products and product candidates which address ophthalmic conditions, announced today that its IOPtiMate system for the treatment of glaucoma has been approved by the Canadian Medical Devices Bureau, allowing the Company to commercialize the surgical system in Canada.

21 Dec 2015

Mirati announces initiation of glesatinib Phase 2 clinical trial in NSCLC patients

Mirati Therapeutics, Inc. today announced that the Phase 2 clinical trial of glesatinib (MGCD265) has commenced. The Company also announced that "glesatinib" is the proposed generic name for MGCD265.

21 Dec 2015

BHF encourages pharmacists to use No Smoking Day as opportunity to promote smoking cessation

The British Heart Foundation (BHF) is encouraging pharmacy staff to use to use No Smoking Day as an opportunity to increase participation among patients by promoting resources and local support services.

21 Dec 2015

SciClone plans to pursue development of SGX942 in the Greater China market

SciClone Pharmaceuticals, Inc. today announced plans to pursue development and registration of SGX942 in the Greater China market, for the treatment of oral mucositis.

21 Dec 2015

Heidelberg neurobiologists identify Dnmt3a2 protein that boosts memory performance

Increasing the level of a certain DNA-modified enzyme in the brain significantly improves cognitive ability. The discovery was made by the research team led by Prof. Dr. Hilmar Bading at the Interdisciplinary Center for Neurosciences of Heidelberg University. Mouse experiments showed that the Dnmt3a2 protein can boost memory performance in the animals.

21 Dec 2015

Dietary cocoa flavanols may benefit cardiovascular health of patients with poor kidney function

Consuming a beverage containing cocoa flavanols improves blood vessel function in patients with kidney failure, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

21 Dec 2015

Regulus begins RG-125(AZD4076) Phase I study for treatment of NASH in patients with type 2 diabetes/pre-diabetes

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, announced today that dosing has begun in a first-in-human Phase I clinical study of RG-125(AZD4076), by its collaboration partner AstraZeneca.

21 Dec 2015

TUM scientists develop small molecule that may allow future patient-specific treatment of cancer tumours

Integrins help cells communicate with and adapt to their environment. Also cancer cells depend on their properties to survive and spread throughout the body. Now scientists at the Technical University of Munich have successfully developed a small, highly active molecule that binds to a specific integrin which operates in many types of cancer.

21 Dec 2015

Certain gut bacteria linked to type 2 diabetes, reveal Russian scientists

A group of Russian scientists, including Dr Elena Kostryukova, the Head of the Laboratory of Postgenomic Research in Biology of the Scientific Research Institute of Physical-Chemical Medicine and a researcher at MIPT (Moscow Institute of Physics and Technology), and Maria Vakhitova, an MIPT postgraduate student, has discovered that the presence of certain bacteria in the gut may be linked to the development of type 2 diabetes.

21 Dec 2015

Enteric nerves of irritable bowel syndrome patients respond poorly to inflammatory substances

For the first time, biopsies of patients with irritable bowel syndrome have shown that the nerves in their gut wall respond poorly to a cocktail of inflammatory substances. This refutes the previous theory that patients with irritable bowel syndrome have an overly sensitive gut.

21 Dec 2015

Medical Condition News

Scientists uncover novel strategy to block cancer's spread, restore tumor vulnerability to chemotherapy

Small airway-on-a-chip enables analysis of human COPD and asthma

Yale researchers reveal why chronic overeating tied to increased risk of depression

Study on myosins may lead to therapies for muscle diseases, cancers

Smokers who see graphic warning labels on cigarette packs have more negative feelings about smoking

Researchers outline novel molecular interactions affecting key cancer pathway in humans

Patients with EGFR-mutated lung cancer benefit more from afatinib as first-line treatment

Alexza reports interim results from AZ-002 Phase 2a study in epilepsy patients

Many patients continue working after metastatic cancer diagnosis, study finds

Nuvo Research announces topline results from WF10 Phase 2 trial for treatment of allergic rhinitis

Bio Light's IOPtiMate system approved in Canada for treatment of glaucoma

Mirati announces initiation of glesatinib Phase 2 clinical trial in NSCLC patients

BHF encourages pharmacists to use No Smoking Day as opportunity to promote smoking cessation

SciClone plans to pursue development of SGX942 in the Greater China market

Heidelberg neurobiologists identify Dnmt3a2 protein that boosts memory performance

Dietary cocoa flavanols may benefit cardiovascular health of patients with poor kidney function

Regulus begins RG-125(AZD4076) Phase I study for treatment of NASH in patients with type 2 diabetes/pre-diabetes

TUM scientists develop small molecule that may allow future patient-specific treatment of cancer tumours

Certain gut bacteria linked to type 2 diabetes, reveal Russian scientists

Enteric nerves of irritable bowel syndrome patients respond poorly to inflammatory substances

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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