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Discovery could lead to better therapies for people with obsessive compulsive disorder

Research led by investigators in veterinary and human medicine has identified genetic pathways that exacerbate severity of canine compulsive disorder in Doberman pinschers, a discovery that could lead to better therapies for obsessive compulsive disorder in people.

27 Feb 2016

Novel therapeutic approach to target monomeric Tau protein

Dementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in the human brain. These diseases represent one of the leading causes of death and disability in the elderly population in the western world, with no current effective therapy.

27 Feb 2016

Older adults have more positive responses than young adults about feeling serenity, loneliness

A new study led by associate professor Rebecca Ready in the department of psychological and brain sciences at the University of Massachusetts Amherst has found that older adults have different, more positive responses than young adults about feelings such as serenity, sadness and loneliness.

27 Feb 2016

Researchers find way to inhibit enzyme responsible for Alzheimer's disease

For decades, intensive research has been conducted on drugs all over the world to treat Alzheimer's patients. Although major progress has been made in diagnostics (the disease can be detected increasingly early and accurately), the therapeutic options remain limited.

27 Feb 2016

Researchers develop new method to screen tumor samples for presence of human polyomaviruses

Human polyomaviruses are commonly found in the population and generally do not produce noticeable symptoms. However, one type of human polyomavirus, the Merkel cell polyomavirus, is known to cause a rare form of skin cancer called Merkel cell carcinoma, and other members of the polyomavirus family can induce non-cancer related diseases in people with compromised immune systems.

27 Feb 2016

Mice with lymphatic defects develop obesity late in life

Lymphatic vessels play multifaceted roles in the body, including the absorption of dietary lipid in the intestines as well as the movement of immune cells throughout the body. Previous work by Guillermo Oliver and colleagues showed that mice with lymphatic defects due to loss of one copy of the Prox1 gene developed obesity late in life.

27 Feb 2016

Bariatric surgery reduces incidence of heart failure exacerbation in patients with morbid obesity

A new study led by Massachusetts General Hospital investigators finds that heart failure patients who underwent bariatric surgery to treat morbid obesity had a significant reduction in the incidence of heart failure exacerbation - a dangerous, sudden worsening of symptoms - in the two years following surgery.

27 Feb 2016

New 3-D microscope allows researchers to look at living cancer cells in controlled microenvironment

UT Southwestern Medical Center researchers have designed and built a microscope capable of creating high-resolution, 3-D images of living cancer cells in realistic, controllable microenvironments.

27 Feb 2016

New imaging study shows how exercise affects the brain

People who exercise have better mental fitness, and a new imaging study from UC Davis Health System shows why. Intense exercise increases levels of two common neurotransmitters -- glutamate and gamma-aminobutyric acid, or GABA -- that are responsible for chemical messaging within the brain.

27 Feb 2016

Researchers develop effective technique for studying high-arched palate using mouse model

Researchers from the laboratory of Paul Trainor, Ph.D., at the Stowers Institute of Medical Research have developed an effective and reliable technique for studying high-arched palate using a mouse model. The methodology could expand research into the genetic aspects of this craniofacial abnormality.

27 Feb 2016

$Uncorrected refractive error responsible for vision impairment in 101 million people worldwide$

Uncorrected refractive error responsible for vision impairment in 101 million people worldwide

Uncorrected refractive error (URE)--nearsightedness, farsightedness, and other focusing problems correctable by prescription lenses--is responsible for moderate to severe vision impairment in 101 million people and blindness in seven million people worldwide, reports a study in the March issue of Optometry and Vision Science, official journal of the American Academy of Optometry.

27 Feb 2016

New drug shows promise against Huntington's disease

A drug that would be the first to target the cause of Huntington's disease (HD) is effective and safe when tested in mice and monkeys, according to data released today that will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

27 Feb 2016

Novartis announces FDA approval of Afinitor for progressive, nonfunctional neuroendocrine tumors of GI

Novartis today announced that the United States Food and Drug Administration approved Afinitor (everolimus) tablets for the treatment of adult patients with progressive, well-differentiated, nonfunctional neuroendocrine tumors (NET) of gastrointestinal (GI) or lung origin that are unresectable, locally advanced or metastatic.

26 Feb 2016

Overweight or obese adults may have poorer episodic memory

Overweight young adults may have poorer episodic memory - the ability to recall past events - than their peers, suggests new research from the University of Cambridge, adding to increasing evidence of a link between memory and overeating.

26 Feb 2016

Number of male smokers in India rise by 36%

The number of men smoking tobacco in India rose by more than one-third to 108 million between 1998 and 2015, according to a new study published today in the journal BMJ Global Health.

26 Feb 2016

First US uterus transplant is successful

The first US uterus transplant was performed this week by a team of surgeons at Cleveland Clinic, Cleveland, Ohio.

26 Feb 2016

Elsevier to launch six new orthopaedic textbooks at AAOS conference

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced that it will launch six new orthopaedic textbooks at this year's American Academy of Orthopaedic Surgeons conference taking place at the Orange County Convention Center, West Building, Orlando, FL, March 1-5, 2016.

26 Feb 2016

EMA grants Orphan Drug Designation to venetoclax for treatment of acute myeloid leukemia

AbbVie, a global biopharmaceutical company, today announced the European Medicines Agency has granted Orphan Drug Designation to venetoclax, an investigational, oral B-cell lymphoma-2 (BCL-2) inhibitor, for the treatment of acute myeloid leukemia (AML).

26 Feb 2016

Nearly two-thirds of herbal medicines have potential health risks to cancer patients

Nearly two-thirds of the herbal medicines used by cancer patients in the Middle East have potential health risks, according to a new survey led by Assistant Professor Eran Ben-Arye, of the Technion-Israel Institute of Technology.

26 Feb 2016

New ways to monitor physical activity at workplace

The science of physical activity at work remains understudied despite widespread acceptance that it plays an important role in health. Now, researchers at the Colorado School of Public Health at the University of Colorado Anschutz Medical Campus have published a comprehensive review of ways to monitor physical activity and tools for occupational exposure scientists.

26 Feb 2016

Medical Condition News

Discovery could lead to better therapies for people with obsessive compulsive disorder

Novel therapeutic approach to target monomeric Tau protein

Older adults have more positive responses than young adults about feeling serenity, loneliness

Researchers find way to inhibit enzyme responsible for Alzheimer's disease

Researchers develop new method to screen tumor samples for presence of human polyomaviruses

Mice with lymphatic defects develop obesity late in life

Bariatric surgery reduces incidence of heart failure exacerbation in patients with morbid obesity

New 3-D microscope allows researchers to look at living cancer cells in controlled microenvironment

New imaging study shows how exercise affects the brain

Researchers develop effective technique for studying high-arched palate using mouse model

Uncorrected refractive error responsible for vision impairment in 101 million people worldwide

New drug shows promise against Huntington's disease

Novartis announces FDA approval of Afinitor for progressive, nonfunctional neuroendocrine tumors of GI

Overweight or obese adults may have poorer episodic memory

Number of male smokers in India rise by 36%

First US uterus transplant is successful

Elsevier to launch six new orthopaedic textbooks at AAOS conference

EMA grants Orphan Drug Designation to venetoclax for treatment of acute myeloid leukemia

Nearly two-thirds of herbal medicines have potential health risks to cancer patients

New ways to monitor physical activity at workplace

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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