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Depression, anxiety co-occur in bipolar disorder patients following mania

Adults with bipolar disorder are just as likely to develop anxiety as depression following an episode of mania, according to data from a national survey of more than 34,000 adults. This finding, published today in Molecular Psychiatry, may expand our understanding of bipolar disorder to include anxiety.

4 May 2016

Important changes in social lives of older adults indicate cognitive decline

Small changes in the social lives of older people are early red flags showing that their thought processes and brain functioning could be on the decline. This is according to Ashwin Kotwal of Brigham and Women's Hospital in the US, who led a study¹ in the Journal of General Internal Medicine, published by Springer.

3 May 2016

New investigational inhibitor JQEZ5 can block specific molecular malfunctions driving cancer

In a step forward in the push for targeted treatments that can block the specific molecular malfunctions driving cancer, University of North Carolina Lineberger Comprehensive Cancer Center researchers have demonstrated how a genetic mutation can drive the most common type of lymphoma as well as melanoma, the deadliest form of skin cancer.

3 May 2016

Hepatitis B virus screening for Asian American adults can help prevent onset of liver diseases

A community-based hepatitis B virus screening effort led by UC Davis researchers found that targeted outreach to Asian American populations can identify groups at high risk for infection and direct them to appropriate follow-up care to help prevent the onset of liver diseases, including cancer.

3 May 2016

Influence of psychiatric comorbidities on all-cause readmissions following elective spine surgery

Winner of the Robert Florin Resident Award, Owoicho Adogwa, MD, presented his research, Association Between Baseline Affective Disorders and 30-day Readmission Rates in Patients Undergoing Elective Spine Surgery, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

3 May 2016

High-intensity exercise, group activity reduce depression among older dementia patients

Both a high-intensity functional exercise programme and a non-exercise group activity, conducted among older care facility residents with dementia, reduced high levels of depressive symptoms. However, exercise had no superior effect on depression, according to a dissertation from Umea University.

3 May 2016

International researchers redefine scientifc concept of obesity

Researchers have determined that obesity involves excessive body weight (including fat and muscle) for a given height and not just excess body fat as was formerly believed.

3 May 2016

Researchers discover new function of genes in Fanconi anemia pathway

Researchers from UT Southwestern Medical Center have identified an important new function of genes in the Fanconi anemia pathway - a finding that could have implications for development of new therapies to treat this disorder and some cancers.

3 May 2016

Community-based social groups could support people with early-onset dementia

Community-based social groups could play a crucial role in empowering people with early-onset dementia, according to new UBC research.

3 May 2016

Yoga, aquatic exercise have positive influence on multiple sclerosis symptoms

Exercise can have a positive influence on certain symptoms of multiple sclerosis: Patients who do yoga and aquatic exercise suffer less from fatigue, depression and paresthesia, as reported by researchers from the University of Basel and the Psychiatric University Clinics Basel in a joint study with colleagues in Iran.

3 May 2016

Study identifies shortfall in uptake of influenza, pneumococcal vaccination among RA patients

Research from The University of Manchester has found a shortfall in the uptake of influenza and pneumococcal vaccinations among those diagnosed with rheumatoid arthritis (RA), potentially increasing their infection risk.

3 May 2016

Researchers examine critical role of hypoxia in induction, amplification of FOP lesions

The cellular response to the lack of oxygen fans the flames of flare-ups in a rare bone disorder. In fibrodysplasia ossificans progressiva (FOP), a mutation triggers bone growth in muscles, which limits motion, breathing, and swallowing, among a host of progressive symptoms.

3 May 2016

Brain receptor that initiates adolescent synaptic pruning appears to go awry in autism, schizophrenia

Research led by SUNY Downstate Medical Center has identified a brain receptor that appears to initiate adolescent synaptic pruning, a process believed necessary for learning, but one that appears to go awry in both autism and schizophrenia.

3 May 2016

Study shows cannabinoid type 2 receptor plays vital role in signal processing of the brain

The cannabinoid type 2 receptor - also called "CB2 receptor" - is a special membrane protein. Its function is to receive chemical signals that control cellular activity. "Until now, this receptor was considered part of the immune system without function in nerve cells.

3 May 2016

Transplanted human islets provide excellent glycemic control for Type 1 diabetes patients with severe hypoglycemia

Northwestern Medicine researchers are co-investigators in a breakthrough clinical trial that found transplanted human islets prevent hypoglycemic events and provide excellent glycemic control for patients with Type 1 diabetes with severe hypoglycemia. The results of the multi-center, single arm, phase III study are published in Diabetes Care on Monday, April 18. The research was funded by National Institute of Health grants through the National Institute of Allergy and Infectious Diseases and the National Institute for Diabetes and Digestive and Kidney Disease.

3 May 2016

LJI study could provide important target for autoimmune disease interventions

Follicular helper T cells (Tfh cells), a rare type of T cells, are indispensable for the maturation of antibody-producing B cells. They promote the proliferation of B cells that produce highly selective antibodies against invading pathogens while weeding out those that generate potentially harmful ones.

3 May 2016

Study examines role of intraventricular transplantation of bone marrow mesenchymal stem cell in stroke patients

Winner of the American Association of Neurological Surgeons International Travel Scholarship, Asra Al Fauzi, MD, IFAANS, presented his research, Intraventricular Transplantation of Autologous Bone Marrow Mesenchymal Stem Cell in Hemorrhagic Stroke, during the 2016 AANS Annual Scientific Meeting.

3 May 2016

$Ibrutinib shows added benefit for refractory mantle cell lymphoma patients$

Ibrutinib shows added benefit for refractory mantle cell lymphoma patients

Ibrutinib is a drug for the treatment of rare diseases. It has been approved for the treatment of adults with chronic lymphocytic leukaemia (CLL) or with relapsed or refractory mantle cell lymphoma (MCL) since 2014, and since 2015 also for the treatment of adults with Waldenström macroglobulinaemia. Regarding the treatment of patients with CLL or MCL, the Federal Joint Committee (G-BA) already conducted a benefit assessment and made a decision in 2015.

3 May 2016

Mepolizumab has no hint of added benefit in eosinophilic asthma

The monoclonal antibody mepolizumab has been approved since the end of 2015 for the treatment of adults with severe refractory eosinophilic asthma. The German Institute for Quality and Efficiency in Health Care now examined in an early benefit assessment whether the drug offers an added benefit for patients in comparison with the appropriate comparator therapy.

3 May 2016

Study confirms under-utilization of medication in patients after bypass surgery

Researchers at Thomas Jefferson University discovered that nearly half of coronary artery bypass patients are not taking statins and aspirin together when they are referred for diagnostic cardiac catheterization at least three years after their initial bypass. Their results are currently in press online in the American Journal of Cardiology.

3 May 2016

Medical Condition News

Depression, anxiety co-occur in bipolar disorder patients following mania

Important changes in social lives of older adults indicate cognitive decline

New investigational inhibitor JQEZ5 can block specific molecular malfunctions driving cancer

Hepatitis B virus screening for Asian American adults can help prevent onset of liver diseases

Influence of psychiatric comorbidities on all-cause readmissions following elective spine surgery

High-intensity exercise, group activity reduce depression among older dementia patients

International researchers redefine scientifc concept of obesity

Researchers discover new function of genes in Fanconi anemia pathway

Community-based social groups could support people with early-onset dementia

Yoga, aquatic exercise have positive influence on multiple sclerosis symptoms

Study identifies shortfall in uptake of influenza, pneumococcal vaccination among RA patients

Researchers examine critical role of hypoxia in induction, amplification of FOP lesions

Brain receptor that initiates adolescent synaptic pruning appears to go awry in autism, schizophrenia

Study shows cannabinoid type 2 receptor plays vital role in signal processing of the brain

Transplanted human islets provide excellent glycemic control for Type 1 diabetes patients with severe hypoglycemia

LJI study could provide important target for autoimmune disease interventions

Study examines role of intraventricular transplantation of bone marrow mesenchymal stem cell in stroke patients

Ibrutinib shows added benefit for refractory mantle cell lymphoma patients

Mepolizumab has no hint of added benefit in eosinophilic asthma

Study confirms under-utilization of medication in patients after bypass surgery

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

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