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New nanoparticle approach can deliver antiobesity drugs directly to fat tissue

Researchers at MIT and Brigham and Women's Hospital have developed nanoparticles that can deliver antiobesity drugs directly to fat tissue. Overweight mice treated with these nanoparticles lost 10 percent of their body weight over 25 days, without showing any negative side effects.

3 May 2016

Researchers develop SpiroCall that can accurately measure lung function over simple phone call

Most people in the developing world who have asthma, cystic fibrosis or other chronic lung diseases have no way to measure how well their lungs are functioning outside of a clinic or doctor visit.

3 May 2016

Snapshots of NMDA receptor activation may help in novel drug design

Structural biologists at Cold Spring Harbor Laboratory and Janelia Research Campus/HHMI, have obtained snapshots of the activation of an important type of brain-cell receptor. Dysfunction of the receptor has been implicated in a range of neurological illnesses, including Alzheimer's disease, Parkinson's disease, depression, seizure, schizophrenia, autism, and injuries related to stroke.

3 May 2016

Fish oil supplements combined with anti-cancer therapy can reduce renal cell carcinoma

Researchers at UC Davis have shown that docosahexaenoic acid (DHA), a fatty acid commonly found in fish and fish oil supplements, reduces renal cell carcinoma invasiveness, growth rate, and blood vessel growth when combined with the anti-cancer therapy regorafenib. The study was published in the journal Molecular Cancer Therapeutics.

3 May 2016

Key method to test compounds for anti-cancer activity in cells flawed, study reveals

The primary method used to test compounds for anti-cancer activity in cells is flawed, Vanderbilt University researchers report May 2 in Nature Methods. The findings cast doubt on methods used by the entire scientific enterprise and pharmaceutical industry to discover new cancer drugs.

3 May 2016

NEI-funded study analyzes outcomes of anti-VEGF therapy for AMD

In a study of nearly 650 people with the eye disease age-related macular degeneration (AMD), half still had vision 20/40 or better, typically good enough to drive or to read standard print, after five years of treatment with anti-VEGF drugs that are injected into the eye. The authors of the study, funded by the National Eye Institute (NEI) at the National Institutes of Health, say those outcomes would have been unimaginable about 10 years ago, prior to the drugs' availability.

3 May 2016

NEI to discuss research advances in regenerative medicine for eye disease at ARVO 2016

The National Eye Institute (NEI), part of NIH, is participating in the Inaugural Press Conference from the Association for Research in Vision and Ophthalmology Annual Meeting (ARVO 2016), the largest gathering of eye and vision researchers in the world, attracting over 11,000 attendees from more than 75 countries.

2 May 2016

Vernakalant drug more effective than Ibutilide in treating recent-onset atrial fibrillation

Vernakalant, a new drug for treating recent-onset atrial fibrillation, has proved to be considerably more effective than Ibutilide, an established drug in this indication. It was able to normalize patients' heart rhythm more rapidly and with fewer side-effects ocurring. This was revealed by a study conducted at the Department of Emergency Medicine at Medical University of Vienna/General Hospital that has recently been published in "Europace", a journal of the European Society of Cardiology.

2 May 2016

Addition of L19-IL2 can increase radiation therapy-induced immune response against tumours

Radiation therapy not only kills cancer cells, but also helps to activate the immune system against their future proliferation. However, this immune response is often not strong enough to be able to cure tumours, and even when it is, its effect is limited to the area that has been irradiated.

2 May 2016

Stereotactic body radiation therapy for NSCLC patients may raise non-cancer mortality risk

Researchers have found that treating patients who have early stage non-small cell lung cancer (NSCLC) with a type of radiotherapy called stereotactic body radiation therapy (SBRT) is associated with a small but increased risk of death from causes other than cancer.

2 May 2016

Rare germ cell tumor creates unique bond between two young women

Morgan Ellison and Madison McDaniel were diagnosed with a rare germ cell tumor of the ovary earlier this year. The two strangers would soon form a unique bond during their treatment in Birmingham, Alabama.

30 Apr 2016

Researchers one step closer to understanding disease origin

Researchers are one step closer to understanding the genetic and biological basis of diseases like cancer, diabetes, Alzheimer's and rheumatoid arthritis - and identifying new drug targets and therapies - thanks to work by three computational biology research teams from the University of Arizona Health Sciences, University of Pennsylvania and Vanderbilt University.

30 Apr 2016

Small doses of cancer drug may be potential treatment for sepsis and other pandemics

Results from laboratory experiments and mouse studies suggest that small doses of drugs from a specific class of approved cancer medications called topoisomerase 1 (top1) inhibitors may protect against the overwhelming immune response to infection that sometimes leads to sepsis, a bacterial condition that kills as many as 500,000 people in the United States each year.

30 Apr 2016

Novel gene therapy can treat pulmonary hypertension linked with heart failure

Scientists have used a novel gene therapy to halt the progression of pulmonary hypertension, a form of high blood pressure in the lung blood vessels that is linked to heart failure, according to a study led by Roger J. Hajjar, MD, Professor of Medicine and Director of the Cardiovascular Research Center at the Icahn School of Medicine at Mount Sinai.

30 Apr 2016

NBI-facilitated bladder tumour surgery can lower risk of cancer recurrence

Research into bladder tumour surgery has found that using narrow band imaging can significantly reduce the risk of disease recurrence.

30 Apr 2016

Scientists unveil reasons why NSAIDs, pain killers may increase heart disease risk

Researchers have known for more than a decade that the risk of heart disease and stroke increases when people take pain relievers like ibuprofen and other non-steroidal anti-inflammatory drugs, or NSAIDs. Now, scientists from the University of California, Davis, have uncovered some of the reasons why these drugs can harm heart tissue.

30 Apr 2016

Modified surgical technique may be effective treatment option for chronic temporal headache

A modified surgical technique may provide a simpler approach to the surgical treatment for one type of chronic headache, according to an "Ideas and Innovations" paper in the May issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS).

30 Apr 2016

Researchers explore effects of adolescent obesity on cognitive performance in adulthood

The Franco-Mexican research explores the cognitive performance in adulthood when the subjects have been exposed to an obesogenic environment during adolescence.

30 Apr 2016

Level of salts in the brain play critical role in controlling sleep-wake cycle

Danish research is behind a new epoch-making discovery, which may prove decisive to future brain research. The level of salts in the brain plays a critical role in whether we are asleep or awake. This discovery may be of great importance to research on psychiatric diseases such as schizophrenia and convulsive fits from lack of sleep as well as post-anaesthetization confusion, according to Professor Maiken Nedergaard.

30 Apr 2016

NCCN publishes series of patient education materials for Non-Hodgkin's Lymphoma

It is estimated that more than 72,000 people in the United States will be diagnosed with Non-Hodgkin's Lymphomas (NHL) in 2016. The sixth leading cancer diagnosis in U.S. men and women, NHL has more than 30 sub-types, each featuring unique treatment choices and challenges.

30 Apr 2016

Medical Condition News

New nanoparticle approach can deliver antiobesity drugs directly to fat tissue

Researchers develop SpiroCall that can accurately measure lung function over simple phone call

Snapshots of NMDA receptor activation may help in novel drug design

Fish oil supplements combined with anti-cancer therapy can reduce renal cell carcinoma

Key method to test compounds for anti-cancer activity in cells flawed, study reveals

NEI-funded study analyzes outcomes of anti-VEGF therapy for AMD

NEI to discuss research advances in regenerative medicine for eye disease at ARVO 2016

Vernakalant drug more effective than Ibutilide in treating recent-onset atrial fibrillation

Addition of L19-IL2 can increase radiation therapy-induced immune response against tumours

Stereotactic body radiation therapy for NSCLC patients may raise non-cancer mortality risk

Rare germ cell tumor creates unique bond between two young women

Researchers one step closer to understanding disease origin

Small doses of cancer drug may be potential treatment for sepsis and other pandemics

Novel gene therapy can treat pulmonary hypertension linked with heart failure

NBI-facilitated bladder tumour surgery can lower risk of cancer recurrence

Scientists unveil reasons why NSAIDs, pain killers may increase heart disease risk

Modified surgical technique may be effective treatment option for chronic temporal headache

Researchers explore effects of adolescent obesity on cognitive performance in adulthood

Level of salts in the brain play critical role in controlling sleep-wake cycle

NCCN publishes series of patient education materials for Non-Hodgkin's Lymphoma

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

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