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Study could open door for new treatment targets to help Parkinson's disease patients walk more easily

Two secrets of one of the brain's most enigmatic regions have finally been revealed. In a pair of new studies, scientists from the Gladstone Institutes have discovered a specific neural circuit that controls walking, and they found that input to this circuit is disrupted in Parkinson's disease.

29 Jan 2016

Scientists trace one of the causes of ischemia renal failure

Every year acute renal failure affects over 13 million people and leads to 1.7 million deaths across the globe. It often develops when an insufficient supply of oxygen reaches the kidneys, a condition called ischemia.

29 Jan 2016

LMU researchers reveal how crystalline deposits induce cell death

Crystal formation plays a defining role in the pathogenesis of a range of common diseases, such as gout and atherosclerosis. Ludwig-Maximilians-Universitaet (LMU) in Munich researchers led by Hans-Joachim Anders have now elucidated how the insoluble deposits induce cell death.

29 Jan 2016

Anticholinergic medications may not be best option for dementia patients in rehab facility

During rehabilitation following an acute hospital stay, medications that block neurotransmitters may be overprescribed to older patients suffering from delirium superimposed on dementia, according to health researchers.

29 Jan 2016

VARI-SU2C Epigenetics Dream Team supports new clinical trial that targets metastatic colorectal cancer

The first clinical trial to move forward as part of the Van Andel Research Institute-Stand Up To Cancer (VARI-SU2C) Epigenetics Dream Team will target metastatic colorectal cancer, the second leading cause of cancer deaths among men and women combined in the U.S.

29 Jan 2016

Mutation or amplification of HER2 gene may lead to lung cancer

A joint study by University of Colorado Cancer Center and Memorial Sloan Kettering Cancer Center published in the Journal of Thoracic Oncology shows two distinct causes of HER2 activation in lung cancer: mutation of the gene and amplification of the gene.

29 Jan 2016

Study finds ethnic differences in coronary heart disease risk within diverse population

In a study of more than 1.3 million Kaiser Permanente members in Northern California that stretched over 10 years, researchers found that blacks, Latinos and Asians generally had lower risk of coronary heart disease compared to whites.

29 Jan 2016

New blood clotting analysis system could help determine effects antithrombotic (anti-clotting) drugs

A new blood clotting analysis system designed in Japan makes it easier to determine the effects of taking one or more antithrombotic (anti-clotting) drugs.

29 Jan 2016

Scientists discover epigenetic switch linked to obesity

It is well known that a predisposition to adiposity lies in our genes. A new study by researchers at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg now shows that it is also crucial how these genes are regulated. The scientists led by Andrew Pospisilik discovered a novel regulatory, epigenetic switch, which causes individuals with identical genetic material, such as monozygotic twins, to either be lean or obese.

29 Jan 2016

Three Case Western faculty members receive funding to develop new diagnostic technologies

Three Case Western Reserve University faculty members have received funding to further develop emerging technologies aimed at malaria, cystic fibrosis, and sickle cell anemia.

29 Jan 2016

Study provides detailed new information about diffuse glioma

An international collaborative study has revealed detailed new information about diffuse glioma, the most common type of tumor found in some 80 percent of adult brain cancer patients, raising hopes that better understanding of these disease groups may aid improved clinical outcomes.

29 Jan 2016

Halaven (eribulin mesylate) approved for treatment of liposarcoma

The U.S. Food and Drug Administration today approved Halaven (eribulin mesylate), a type of chemotherapy, for the treatment of liposarcoma (a specific type of soft tissue sarcoma) that cannot be removed by surgery (unresectable) or is advanced (metastatic). This treatment is approved for patients who received prior chemotherapy that contained an anthracycline drug.

28 Jan 2016

New technique may reduce need for amputation in patients with critical limb ischemia

A new imaging technique could reduce the need for amputation in patients with critical limb ischemia, according to a study publised today in the scientific journal JACC.

28 Jan 2016

Researchers discover potential candidates for development of novel targeted therapies for blood cancers

A research team from the Department of Pharmacology and Therapeutics at Roswell Park Cancer Institute has discovered a new class of small-molecule compounds that are good candidates for development of novel targeted therapies in the treatment of leukemia and lymphoma.

28 Jan 2016

Depression care management prevents death among older adults with diabetes

According to a new study published in the Journal of the American Geriatrics Society, effective treatment for depression could go a long way toward improving health status and even preventing death among older adults who also have diabetes.

28 Jan 2016

Involving family members in care may reduce hospital readmissions

A new study finds that educating and involving family members in the care of a loved one who has memory loss may significantly reduce hospital readmissions.

28 Jan 2016

Scientists pin down molecular process linked to schizophrenia origin

For the first time, researchers have managed to home in on a molecular process in the brain that contributes to the development of schizophrenia.

28 Jan 2016

EHCI: European healthcare steadily improving

European healthcare is steadily improving, in spite of alarm bells about financial crisis austerity measures, aging population and migration turmoil.

28 Jan 2016

Brain-derived neurotrophic factor linked to slower cognitive decline in older people

Older people with higher amounts of a key protein in their brains also had slower decline in their memory and thinking abilities than people with lower amounts of protein from the gene called brain-derived neurotrophic factor, or BDNF, according to a study published in the January 27, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Jan 2016

New findings offer roadmap for development of novel therapies to target common brain disorders

Scientists have pinpointed the cells that are likely to trigger common brain disorders, including Alzheimer's disease, Multiple Sclerosis and intellectual disabilities.

28 Jan 2016

Medical Condition News

Study could open door for new treatment targets to help Parkinson's disease patients walk more easily

Scientists trace one of the causes of ischemia renal failure

LMU researchers reveal how crystalline deposits induce cell death

Anticholinergic medications may not be best option for dementia patients in rehab facility

VARI-SU2C Epigenetics Dream Team supports new clinical trial that targets metastatic colorectal cancer

Mutation or amplification of HER2 gene may lead to lung cancer

Study finds ethnic differences in coronary heart disease risk within diverse population

New blood clotting analysis system could help determine effects antithrombotic (anti-clotting) drugs

Scientists discover epigenetic switch linked to obesity

Three Case Western faculty members receive funding to develop new diagnostic technologies

Study provides detailed new information about diffuse glioma

Halaven (eribulin mesylate) approved for treatment of liposarcoma

New technique may reduce need for amputation in patients with critical limb ischemia

Researchers discover potential candidates for development of novel targeted therapies for blood cancers

Depression care management prevents death among older adults with diabetes

Involving family members in care may reduce hospital readmissions

Scientists pin down molecular process linked to schizophrenia origin

EHCI: European healthcare steadily improving

Brain-derived neurotrophic factor linked to slower cognitive decline in older people

New findings offer roadmap for development of novel therapies to target common brain disorders

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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