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Patients with achilles tendon disorders fare better with conservative treatment

Achilles tendon disorders are common and often misdiagnosed, with about 25 percent of ruptures missed during initial examination, but the prognosis is favorable for the vast majority of patients, according to researchers from Rowan University School of Osteopathic Medicine and the Rothman Institute of Jefferson Medical College.

30 Oct 2015

ESRD patients with multiple myeloma living longer than before, shows study

The risk of kidney failure caused by multiple myeloma appears to be declining, and survival is lengthening for patients who do develop kidney failure due to this cancer.

30 Oct 2015

Mallinckrodt announces approval of INOmax for cardiovascular surgery in Australia and Japan

Mallinckrodt plc, a leading specialty biopharmaceutical company, today announced that INOmax (nitric oxide) for inhalation has received regulatory approval in Australia and Japan for pulmonary hypertension in conjunction with heart surgery.

30 Oct 2015

Isis Pharmaceuticals begins ISIS-FXI Rx Phase 2 study in patients with ESRD on hemodialysis

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 2 study evaluating ISIS-FXIRx in patients with end-stage renal disease (ESRD) on hemodialysis. In May 2015, Isis entered into an exclusive license agreement with Bayer HealthCare (Bayer) to develop and commercialize ISIS-FXIRx for the prevention of clotting disorders.

30 Oct 2015

Findings could lead to new treatment for ALS, dementia

University of Toronto (U of T) researchers are proposing a new way of understanding Amyotrophic Lateral Sclerosis (ALS), the devastating and incurable neurological disease. Their findings, published today in the journal Neuron, could be a major milestone on the path to a treatment for both ALS and dementia.

30 Oct 2015

Reptile food causes allergic reactions

Reptiles are often chosen as pets when an allergy risk exists within a family and the choice is made to avoid potentially allergenic pets such as dogs, cats or guinea pigs.

30 Oct 2015

Women with elevated breast cancer risk can benefit from regular physical activity

Regular physical activity could play a role in helping women at high-risk of breast cancer delay the need for drastic preventive measures such as prophylactic mastectomy, according to new research led by the Perelman School of Medicine at the University of Pennsylvania.

30 Oct 2015

Novel enzyme therapy offers possible treatment for cocaine overdose

A long-acting enzyme that rapidly and safely metabolizes cocaine in the blood stream is currently being investigated in animal models as a possible treatment for cocaine overdose.

30 Oct 2015

Study suggests a neural pathway through which early life stress may contribute to depression

Early life stress is a major risk factor for later episodes of depression. In fact, adults who are abused or neglected as children are almost twice as likely to experience depression.

30 Oct 2015

Exercise can protect brain function, reduce occurrence of PTSD

Experiencing a traumatic event often results in an acute stress response and the lingering memory may lead to mental and physical changes that negatively impact one's health.

30 Oct 2015

Single gene variation may influence obesity in children, adults

A single variation in the gene for brain-derived neurotropic factor (BDNF) may influence obesity in children and adults, according to a new study funded by the National Institutes of Health.

30 Oct 2015

Gut bacteria may increase risk of metabolic syndrome

An excess of bacteria in the gut can change the way the liver processes fat and could lead to the development of metabolic syndrome, according to health researchers.

30 Oct 2015

New clinical trial on breast cancer may help treat and control disease

A new clinical trial at Sanford Health is exploring how genetic changes that occur during breast cancer might help health care providers better identify, treat and control the disease.

30 Oct 2015

Study reveals mechanism behind protein-related diseases

Dartmouth researchers have found that some proteins turn into liquid droplets on the way to becoming toxic solids implicated in neurodegenerative diseases and other genetic disorders.

30 Oct 2015

Halozyme Therapeutics announces initiation of rivipansel Phase 1 clinical trial

Halozyme Therapeutics, Inc. today announced that the first healthy subject has been dosed in a Phase 1 clinical trial evaluating the safety, tolerability and pharmacokinetics of a subcutaneous formulation of rivipansel, a compound discovered by GlycoMimetics, Inc. and being developed by Pfizer Inc., using Halozyme's ENHANZE formulation.

30 Oct 2015

New magnetic field delivery method could help treat traumatic brain injury

Treating traumatic brain injury (TBI) using stem cell therapy is an important area of current research. However, injecting stem cells into the central nervous system has serious drawbacks, including intracranial hemorrhage and cells failing to reach TBI-affected areas of the brain.

30 Oct 2015

Researchers identify molecular switch that can convert unhealthy white fat into energy-burning brown fat

A research team led by UC San Francisco scientists has identified a molecular switch capable of converting unhealthy white fat into healthy, energy-burning brown fat in mice. Drugs that flip this switch rapidly reduced obesity and diabetes risk factors in mice fed a high fat diet.

30 Oct 2015

FAU, Max Planck ink new agreement to recruit and retain promising scientists

Florida Atlantic University, the Max Planck Florida Institute for Neuroscience and the Max Planck Society based in Germany, have signed an innovative agreement to facilitate a research and education program that will recruit promising scientists to MPFI and FAU.

30 Oct 2015

Counting bites: A cost-effective option for losing weight

Forget counting calories. The next new diet trend could be as simple as counting bites. A new study from BYU health science researchers found people who counted bites over a month's time lost roughly four pounds--just about what the CDC recommends for "healthy" weight loss.

30 Oct 2015

Study shows link between physical activity and depression in patients at risk for heart disease

In the study published in the prestigious American Journal of Medicine using data from the Nord-Trøndelag Health Study in Norway, the researchers studied whether pattern of leisure time physical activity among 189 patients prior to being hospitalized with first heart attack was associated with level of depressive symptoms after the initial heart attack.

30 Oct 2015