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Drug that relieves opioid-induced constipation may help some cancer patients live longer

Patients with advanced cancers who took a drug designed to relieve constipation caused by pain killers lived longer and had fewer reports of tumor progression than cancer patients who did not receive the drug, according to results presented October 27 at the 2015 meeting of the American Society of Anesthesiologists in San Diego. This is the first study in humans to associate opioid blockade with improved survival.

28 Oct 2015

Researchers identify role of cGAS enzyme in autoimmune diseases

Activating an enzyme that sounds an alarm for the body's innate immune system causes two lethal autoimmune diseases in mice, while inhibiting the same enzyme rescues them, UT Southwestern Medical Center researchers report.

28 Oct 2015

Study suggests potential new way to block cancer-causing gene

A new study suggests a potential new way to block one of the most common cancer-causing genes, without causing severe side effects.

28 Oct 2015

Study finds overall decreasing trend in leading causes of death

An analysis of deaths in the United States between 1969 and 2013 finds an overall decreasing trend in the age-standardized death rate for all causes combined and for heart disease, cancer, stroke, unintentional injuries, and diabetes, although the rate of decrease appears to have slowed for heart disease, stroke, and diabetes, according to a study in the October 27 issue of JAMA.

28 Oct 2015

Biodegradable polymer could help heal the bones of patients with orthopedic injuries

A plastic derived from cornstarch combined with a volcanic ash compound, Montmorillonite clay, could help heal the bones of hundreds of thousands of patients with orthopedic injuries who need bone replacement after tumor removal, spinal fusion surgery or fracture repair.

28 Oct 2015

Stopping cholesterol medications before surgery may increase risk of death during recovery

Patients who stop taking cholesterol medications before surgery are following outdated recommendations, and significantly increasing their risk of death if they don't resume taking the medications within two days after surgery, according to a study of more than 300,000 patients being presented at the ANESTHESIOLOGY 2015 annual meeting.

28 Oct 2015

New method to grow 3D pancreatic cancer organoid may help test drug responses and personalized treatments

The development of a new method to grow three-dimensional organoid cultures of pancreatic tumors directly from patients' surgical tissue offers a promising opportunity for testing targeted therapies and drug responses and personalizing treatments in a rapid, cost-effective manner.

28 Oct 2015

Risk of depression recurrence significantly lower for people with complete symptom resolution

People who have had an episode of major depression are at high risk for having another episode. Now, researchers at University of California, San Diego School of Medicine have found that the risk of recurrence is significantly lower for people with complete, rather than partial depressive symptom resolution.

28 Oct 2015

Watching too much TV increases risk of death

On average, 80% of American adults watch 3.5 hours of television per day and multiple observational studies have demonstrated a link between TV viewing and poorer health. In this new study published in the December issue of the American Journal of Preventive Medicine, investigators reported an association between increasing hours of television viewing per day and increasing risk of death from most of the major causes of death in the United States.

28 Oct 2015

Wyss Institute, UMass team up to develop drug-device combination for treating blood clots in stroke patients

Scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University developing novel nanotherapeutics for clearing obstructed blood vessels have teamed up with researchers at University of Massachusetts' New England Center for Stroke Research (NECSTR) to develop a new, highly effective drug-device combination for treating life-threatening blood clots in patients with stroke.

28 Oct 2015

Researchers compare effectiveness of combination therapy for black patients with asthma

Among black adults with asthma treated with an inhaled corticosteroid, adding a long-acting beta-agonist did not improve the time to an asthma exacerbation compared with adding the anticholinergic tiotropium, according to a study in the October 27 issue of JAMA.

28 Oct 2015

Endocrine Society to host Congressional briefing on November 4 to combat diabetes epidemic

The Endocrine Society is hosting a Congressional briefing on November 4 to examine policies to help the 29 million Americans who have diabetes and the 86 million who are likely to develop the disease.

28 Oct 2015

Virginia Tech researchers study how specific cytokine influences gene expression patterns in T helper cells

Environment can make all the difference in behavior - even at the cellular level. Scientists at the Virginia Tech Carilion Research Institute have discovered even a small shift in environmental factors can change how a cell in the immune system matures.

28 Oct 2015

Diabetic patients at increased risk for developing surgical site infections

Diabetic patients are at considerably increased risk for developing surgical site infections (SSIs) while undergoing most types of surgeries, compared to non-diabetic patients, according to a new study published online today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

28 Oct 2015

WSU collaborates with Botanisol to study and develop new anti-inflammatory drug

Work on a new anti-inflammatory drug developed from the medicinal/spice plant turmeric recently received funding from a $225,000 grant from the National Institutes of Health National Center for Complementary and Integrative Health.

28 Oct 2015

Oral formulation of insulin shows promise in management of blood glucose in diabetic rats

An intestinal patch device containing insulin that can be swallowed in the form of a capsule, in development by researchers at University of California Santa Barbara, has demonstrated efficacy of blood glucose management in diabetic rats. This work is being presented Oct. 27 at the 2015 American Association of Pharmaceutical Scientists Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in Orlando, Fla. Oct. 25-29.

28 Oct 2015

Lithium chloride could offer effective treatment against osteoarthritis

Bioengineers from Queen Mary University of London have shown for the first time that lithium chloride, a common drug used to treat mental health disorders, could offer an effective treatment against osteoarthritis by disrupting the length of the cells' antennae called primary cilia.

28 Oct 2015

Pharmacy-led glycemic control program improves outcomes for surgical patients with diabetes

A pharmacy-led glycemic control program is linked to improved outcomes for surgical patients with diabetes and those who develop stress-induced hyperglycemia or high blood sugars as a result of surgery, according to a new Kaiser Permanente study published in the American Journal of Pharmacy Benefits.

28 Oct 2015

Experts call for better risk profiling for GI cancers

Cancers of the gastrointestinal (GI) tract continue to exert their toll across Europe, with many diagnosed too late for effective treatment. Bowel cancer screening programmes are now underway in most European countries, but screening for other GI cancers is patchy and not necessarily well-targeted.

28 Oct 2015

Imlygic approved for treatment of melanoma lesions in the skin and lymph nodes

The U.S. Food and Drug Administration today approved Imlygic (talimogene laherparepvec), the first FDA-approved oncolytic virus therapy, for the treatment of melanoma lesions in the skin and lymph nodes.

28 Oct 2015

Medical Condition News

Drug that relieves opioid-induced constipation may help some cancer patients live longer

Researchers identify role of cGAS enzyme in autoimmune diseases

Study suggests potential new way to block cancer-causing gene

Study finds overall decreasing trend in leading causes of death

Biodegradable polymer could help heal the bones of patients with orthopedic injuries

Stopping cholesterol medications before surgery may increase risk of death during recovery

New method to grow 3D pancreatic cancer organoid may help test drug responses and personalized treatments

Risk of depression recurrence significantly lower for people with complete symptom resolution

Watching too much TV increases risk of death

Wyss Institute, UMass team up to develop drug-device combination for treating blood clots in stroke patients

Researchers compare effectiveness of combination therapy for black patients with asthma

Endocrine Society to host Congressional briefing on November 4 to combat diabetes epidemic

Virginia Tech researchers study how specific cytokine influences gene expression patterns in T helper cells

Diabetic patients at increased risk for developing surgical site infections

WSU collaborates with Botanisol to study and develop new anti-inflammatory drug

Oral formulation of insulin shows promise in management of blood glucose in diabetic rats

Lithium chloride could offer effective treatment against osteoarthritis

Pharmacy-led glycemic control program improves outcomes for surgical patients with diabetes

Experts call for better risk profiling for GI cancers

Imlygic approved for treatment of melanoma lesions in the skin and lymph nodes

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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