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Plitidepsin in combination with dexamethasone shows top-line results in Phase III multiple myeloma trial

PharmaMar today announced positive top-line results of its Phase III clinical trial -ADMYRE- with Aplidin (plitidepsin) in combination with dexamethasone versus dexamethasone alone in patients with relapsed/refractory multiple myeloma (MM).

2 Apr 2016

USC study finds coffee consumption decreases colorectal cancer risk

Whether you like your coffee black, decaf, half-caff or even instant, feel free to drink up. Researchers at the University of Southern California (USC) Norris Comprehensive Cancer Center of Keck Medicine of USC have found that coffee consumption decreases the risk of colorectal cancer.

2 Apr 2016

Joslin scientists identify new mechanism in development of obesity-induced insulin resistance

In obesity, the body's immune system can treat tissues as if they are suffering from a low-grade chronic infection. This obesity-induced inflammation is an important contributor to insulin resistance, a condition that can progress into type 2 diabetes.

2 Apr 2016

U of S-led researchers develop novel class of compounds for effective cancer treatment

A novel class of compounds developed by a University of Saskatchewan-led research team could yield more effective and less toxic chemotherapy drugs to treat cancer.

2 Apr 2016

New SPOR Network launched to transform health outcomes of diabetes patients

A new national research network was launched today to transform the health outcomes of individuals with diabetes and its related complications. It will be led by two of Canada's top researchers in the field and includes researchers conducting leading-edge health and biomedical research at nine institutions across the country.

2 Apr 2016

Better understanding of cell death mechanism could lead to more efficient cancer immunotherapy

Researchers in the group of Prof. Dr. Peter Vandenabeele show that killed tumour cells can serve as a potent vaccine that stimulates the immune system to prevent the outgrowth of cancer cells.

2 Apr 2016

Lund researchers discover new biomarker that can predict type 2 diabetes risk

Researchers at Lund University in Sweden have found a new type of biomarker that can predict the risk of type 2 diabetes, by detecting epigenetic changes in specific genes through a simple blood test. The results are published today in Nature Communications.

2 Apr 2016

MicroRNA controls tumor cell proliferation in most aggressive large B-cell lymphoma

A recent study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine showed that a microRNA called miR-181a dampens signals from the cancer-driving NFκB protein pathway in the most aggressive large B-cell lymphomas (DLBCL). By reducing NFκB signaling, miR-181a controls tumor cell proliferation and survival and could be the target of novel therapies. The study was published in the journal Blood.

2 Apr 2016

Better oral hygiene, regular dental visits could slow down cognitive decline in older adults

Better oral hygiene and regular dental visits may play a role in slowing cognitive decline as people age, although evidence is not definitive enough to suggest that one causes the other.

2 Apr 2016

Common viruses could produce mild to lethal cardiac injury

A review article has been published in the journal Current Pharmaceutical Design which provides an overview of therecent literature discussing the different clinical forms of heart disease resulting from virus infections including the prognosis, and current therapies.

2 Apr 2016

Loyola to conduct clinical trial of new procedure to treat atrial fibrillation

Loyola Medicine is enrolling patients in a landmark clinical trial of a new procedure to treat atrial fibrillation, the most common type of irregular heartbeat.

2 Apr 2016

Mindfulness training can help manage painful cycles of thoughts in veterans with PTSD

Like an endlessly repeating video loop, horrible memories and thoughts can keep playing over and over in the minds of people with post-traumatic stress disorder. They intrude at the quietest moments, and don't seem to have an off switch.

2 Apr 2016

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

Several new immunotherapeutic antibodies that inhibit checkpoint receptors on T cells to restimulate the immune system to target tumors have been approved to treat advanced stage lung cancer and melanoma; however, only 20 percent of lung cancer patients show a response to these agents.

2 Apr 2016

European researchers aim to spare people with type 1 diabetes from lifelong insulin therapy

More and more children in Europe and the USA are suffering from diabetes. A Group of European Researchers has now joined forces under the leadership of the Gothe University Frankfurt. They are searching for a new method in order to spare people with Diabetes type 1 from lifelong insulin therapy.

2 Apr 2016

Sleep problems predict chronic pain in emerging adults

For at least some groups of "emerging adults," sleep problems are a predictor of chronic pain and worsening pain severity over time, suggests a study in PAIN, the official publication of the International Association for the Study of Pain.

2 Apr 2016

Health behavior interventions can help adolescent, young adult cancer survivors

A healthy lifestyle is especially important for young adult and teenage survivors of cancer, and how health behavior messages related to diet, exercise, smoking, and alcohol consumption are developed and presented may impact their effectiveness in this population.

2 Apr 2016

Mimicry may be useful tool to help Alzheimer's patients regain lost abilities

Alzheimer's disease is the sixth leading cause of death in the U.S., according to the Alzheimer's Association. There is no cure and no way to slow or prevent the illness. But, patients can still benefit from both physical and cognitive rehabilitation, and researchers are learning that mimicry may be a useful tool to help them regain lost abilities.

2 Apr 2016

Researchers uncover vital clues of how the brain erases long term memories

Vital clues about how the brain erases long term memories have been uncovered by researchers. The study in rats reveals how forgetting can be the result of an active deletion process rather than a failure to remember.

2 Apr 2016

Altered metabolism of two essential amino acids helps drive development of glioblastoma

The altered metabolism of two essential amino acids helps drive the development of the most common and lethal form of brain cancer, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

2 Apr 2016

Excess activation of LOX may play causative role in progression of cardiac failure

Heart failure is a progressive condition, where structural and functional alterations of the ventricle limit the ability of the heart to either fill or eject blood. There are approximately 550,000 new cases of heart failure each year with a prevalence of nearly 5 million; most patients die within five years of diagnosis.

2 Apr 2016

Medical Condition News

Plitidepsin in combination with dexamethasone shows top-line results in Phase III multiple myeloma trial

USC study finds coffee consumption decreases colorectal cancer risk

Joslin scientists identify new mechanism in development of obesity-induced insulin resistance

U of S-led researchers develop novel class of compounds for effective cancer treatment

New SPOR Network launched to transform health outcomes of diabetes patients

Better understanding of cell death mechanism could lead to more efficient cancer immunotherapy

Lund researchers discover new biomarker that can predict type 2 diabetes risk

MicroRNA controls tumor cell proliferation in most aggressive large B-cell lymphoma

Better oral hygiene, regular dental visits could slow down cognitive decline in older adults

Common viruses could produce mild to lethal cardiac injury

Loyola to conduct clinical trial of new procedure to treat atrial fibrillation

Mindfulness training can help manage painful cycles of thoughts in veterans with PTSD

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

European researchers aim to spare people with type 1 diabetes from lifelong insulin therapy

Sleep problems predict chronic pain in emerging adults

Health behavior interventions can help adolescent, young adult cancer survivors

Mimicry may be useful tool to help Alzheimer's patients regain lost abilities

Researchers uncover vital clues of how the brain erases long term memories

Altered metabolism of two essential amino acids helps drive development of glioblastoma

Excess activation of LOX may play causative role in progression of cardiac failure

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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