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Mitochondrial Pyruvate Carrier could potentially be a new drug target to treat diabetes

High blood sugar is a defining characteristic of Type 2 diabetes and the cause of many of the condition's complications, including kidney failure, heart disease, and blindness. Most diabetes medications aim to maintain normal blood sugar (glucose) levels and prevent high blood sugar by controlling insulin.

3 Sep 2015

Common drug used for treating fungal infections in lung transplant recipients increases risk for skin cancer, death

Voriconazole, a prescription drug commonly used to treat fungal infections in lung transplant recipients, significantly increases the risk for skin cancer and even death, according to a new study by UC San Francisco researchers.

3 Sep 2015

HUYA Bioscience International expands HBI-8000 clinical trials for breast cancer

HUYA Bioscience International (HUYA) today announced expanding clinical trials with its lead cancer drug, HBI-8000, starting with a Phase 1 combination trial in support of a breast cancer program to be conducted in the United States.

3 Sep 2015

New computational method reveals links between bacterial growth rates and type II diabetes, IBD

It is increasingly clear that the thousands of different bacteria living in our intestinal tract - our microbiome - have a major impact on our health. But the details of the microbiome's effects are still fairly murky.

3 Sep 2015

Children's Hospital Los Angeles receives $2 million to spur research on brain, spinal cord tumors

A life-changing event for a Los Angeles family has resulted in their funding an endowment to support The Kort Family Foundation Brain and Spinal Cord Tumor Research Program in the Division of Neurosurgery at Children's Hospital Los Angeles.

3 Sep 2015

More men with breast cancer are opting for double mastectomy

The number of men with invasive cancer in one breast who undergo surgery to remove both breasts is on the rise, according to a new report published in JAMA Surgery.

3 Sep 2015

Valerion announces positive results from non-clinical pilot study of VAL-1221 for treatment of Pompe disease

Valerion Therapeutics, LLC yesterday announced positive results from a non-clinical "proof of concept" pilot study for a novel humanized antibody and acid alpha glucosidase (GAA) fusion candidate for the treatment of Pompe disease.

3 Sep 2015

Regulatory T cells may reduce susceptibility to allergies

Susceptibility to allergies reduced by increased production of regulatory T cells. This is the main finding of a current study being conducted at the Institute of Immunology at MedUni Vienna, headed up by Winfried F. Pickl. The initial results of this study by Alina Neunkirchner, which looks at the root cause of the development of allergies, are being presented at the European Congress of Immunology, which starts in Vienna this Sunday (6 - 9 September 2015, Austria Center Vienna).

3 Sep 2015

Depressive symptoms remain high in coastal areas affected by the Great East Japan Earthquake

A second round of aggregate findings from a study by Tohoku University's Tohoku Medical Megabank Organization (ToMMo) has revealed that depressive symptoms continue to be higher in coastal areas than in inland areas affected by the Great East Japan Earthquake and the tsunami that followed.

3 Sep 2015

Preserving natural structure of dietary fibre during food production can help lower blood sugar levels

A new study led by scientists at King's College London shows that preserving the natural structure of dietary fibre during food production can help to slow the rise in blood sugar levels after a meal.

3 Sep 2015

Children in northern Israel emergency departments receive equal pain treatment, regardless of ethnicity

Children with broken bones or joint dislocations in northern Israel emergency departments received equal pain treatment, regardless of their ethnicity or the ethnicity of the nurses who treated them, even during a period of armed conflict between the two ethnic groups.

3 Sep 2015

Research findings may help explain why drug treatments for addiction, depression are not always effective

New research may help explain why drug treatments for addiction and depression don't work for some patients. The conditions are linked to reward and aversion responses in the brain. Working in mice, researchers at Washington University School of Medicine in St. Louis have discovered brain pathways linked to reward and aversion behaviors are in such close proximity that they unintentionally could be activated at the same time.

3 Sep 2015

Imetelstat drug shows promise in treating patients with myelofibrosis

Imetelstat, a novel drug that targets telomerase, has demonstrated potential value in treating patients with myelofibrosis, according to the results of a study published today in the New England Journal of Medicine.

3 Sep 2015

Diabetes may be linked to buildup of brain tangles associated with Alzheimer’s disease

Diabetes may be linked to the buildup of tangles or tau in the brain, separate from Alzheimer's disease, according to a new study published in the September 2, 2015, online version of Neurology, the medical journal of the American Academy of Neurology.

3 Sep 2015

Novel approach to reduce 'bad' lipids in blood circulation

Xian-Cheng Jiang, PhD, professor of cell biology at SUNY Downstate Medical Center, has led a study identifying a new approach for lowering "bad" lipids in blood circulation, a critical means to combat devastating cardiovascular diseases such as atherosclerosis. The research was published in the online edition of Gastroenterology.

3 Sep 2015

Study reveals new epigenetic mechanism underlying progression of cancer tumors

Aggressive cancer growth and alterations in gene activity without changes in DNA sequence (epigenetics) are associated with mutant p53 proteins, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

3 Sep 2015

ISU researcher examines how supplements, resistance training improve muscle strength in older adults

The loss of muscle strength and function, what's known as sarcopenia, is a natural part of aging. It's also a growing public health concern because of the risk for falls, injury and decline in quality of life. That's why an Iowa State University researcher is working to slow or reverse the progression of sarcopenia.

3 Sep 2015

Researchers create method to watch activity of motor neurons in real time

When you're taking a walk around the block, your body is mostly on autopilot--you don't have to consciously think about alternating which leg you step with or which muscles it takes to lift a foot and put it back down. That's thanks to a set of cells in your spinal cord that help translate messages between your brain and your motor neurons, which control muscles.

3 Sep 2015

University of Basel scientists identify genes that play central role in development of Alzheimer's disease

Genes are not only important for regular memory performance, but also for the development of Alzheimer's disease. Researchers at the University of Basel now identified a specific group of genes that plays a central role in both processes. This group of molecules controls the concentration of calcium ions inside the cell.

3 Sep 2015

Exercise training improves quality of life for patients with pulmonary hypertension

Exercise training for patients with pulmonary hypertension was shown to be safe and to improve quality of life, according to an analysis by UT Southwestern Medical Center cardiologists of studies involving more than 400 participants.

3 Sep 2015

Medical Condition News

Mitochondrial Pyruvate Carrier could potentially be a new drug target to treat diabetes

Common drug used for treating fungal infections in lung transplant recipients increases risk for skin cancer, death

HUYA Bioscience International expands HBI-8000 clinical trials for breast cancer

New computational method reveals links between bacterial growth rates and type II diabetes, IBD

Children's Hospital Los Angeles receives $2 million to spur research on brain, spinal cord tumors

More men with breast cancer are opting for double mastectomy

Valerion announces positive results from non-clinical pilot study of VAL-1221 for treatment of Pompe disease

Regulatory T cells may reduce susceptibility to allergies

Depressive symptoms remain high in coastal areas affected by the Great East Japan Earthquake

Preserving natural structure of dietary fibre during food production can help lower blood sugar levels

Children in northern Israel emergency departments receive equal pain treatment, regardless of ethnicity

Research findings may help explain why drug treatments for addiction, depression are not always effective

Imetelstat drug shows promise in treating patients with myelofibrosis

Diabetes may be linked to buildup of brain tangles associated with Alzheimer’s disease

Novel approach to reduce 'bad' lipids in blood circulation

Study reveals new epigenetic mechanism underlying progression of cancer tumors

ISU researcher examines how supplements, resistance training improve muscle strength in older adults

Researchers create method to watch activity of motor neurons in real time

University of Basel scientists identify genes that play central role in development of Alzheimer's disease

Exercise training improves quality of life for patients with pulmonary hypertension

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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