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UB study traces how enigmatic molecules help cancer self-destruct

You've probably never heard of "sphingolipids" before. But these curiously named organic compounds play a vital role in one of humanity's most well-known diseases: cancer.

18 Dec 2015

Kitov announces more data from Phase III trial on the favorable blood pressure effects of KIT-302

Kitov Pharmaceuticals, an innovative biopharmaceutical company focused on late-stage drug development, today announced more data from its successfully concluded Phase III trial for its lead drug candidate, KIT-302. Data showed the favorable blood pressure effects of KIT-302 were present in all blood pressure variables measured in the study.

18 Dec 2015

Chi-Med announces initiation of Phase III sulfatinib registration trial in patients with NETs in China

Hutchison China MediTech Limited today announces that Hutchison MediPharma Limited, its drug R&D subsidiary, has initiated SANET-ep, a Phase III sulfatinib (HMPL-012) registration trial in China in patients with extra-pancreatic neuroendocrine tumors ("NETs"), which are all non-pancreatic NETs, including, for example, NETs originating in the lymph, lung and across the gastrointestinal tract.

18 Dec 2015

New test can help detect cancer and diabetes biomarkers in bloodstream

A new test for detecting biomarkers for cancer and diabetes is more than 1000x more detailed and 100% faster than existing methods, new research by the University of Warwick suggests.

18 Dec 2015

New nanotechnology approach could transform gliomas from death sentence into treatable condition

An MRI contrast agent that can pass through the blood-brain barrier will allow doctors to detect deadly brain tumors called gliomas earlier, say Penn State College of Medicine researchers. This ability opens the door to make this fatal cancer treatable.

18 Dec 2015

Novel drug candidate prevents nerve cell damage in mouse model of Parkinson's disease

A team of scientists at the University of Nebraska Medical Center (UNMC) and Longevity Biotech, Inc., has demonstrated that neuroprotection could be attained in preclinical models by a novel drug candidate that changes immune responses.

18 Dec 2015

Presence of mirror in dining rooms can reduce perceived tastiness of unhealthy food

People often choose the unhealthy food because they think it is tastier. Aiming for solutions promoting healthy eating practices and ultimately combating obesity, this research shows that the presence of a mirror in a consumption setting can reduce the perceived tastiness of unhealthy food, which consequently reduces its consumption.

18 Dec 2015

Researchers elucidate structure of mTORC1 protein

For a long time it has been known that the protein TOR - Target of Rapamycin - controls cell growth and is involved in the development of diseases such as cancer and diabetes. Researchers at the University of Basel's Biozentrum together with scientists from ETH Zurich have now examined the structure of mammalian TOR complex 1 (mTORC1) in more detail.

18 Dec 2015

AES Annual Meeting takes our understanding of epilepsy to next level

Epilepsy remains one of the most common neurological conditions, affecting one in 26 Americans in their lifetime, with one-third having a form of the condition that resists treatment or effective management. With those statistics in mind, more than 5,200 neurologists, scientists, nurses and health professionals came to Philadelphia December 4-8 for the 2015 American Epilepsy Society Annual Meeting to discuss new discoveries and emerging technologies that can lead to more effective treatment.

18 Dec 2015

Case Western scientist to lead a pair of studies to develop more effective treatment for CF

A scientist at Case Western Reserve University Frances Payne Bolton School of Nursing will lead a pair of studies to develop more effective treatment for symptoms of cystic fibrosis (CF), a life-threatening genetic disease that causes persistent lung infections and progressively limits the ability to breathe.

18 Dec 2015

Anti-aging Glycopeptide can improve efficacy of cell transplant treatments for diabetes patients

An antifreeze glycopeptide that mimics a naturally occurring glycoprotein found in Arctic fish is helping to significantly improve the efficacy of cell transplant treatments for diabetes patients--a procedure that transplants insulin producing islets to render them insulin independent for periods of time.

18 Dec 2015

Patient's mental health prior to radical cystectomy can influence postoperative outcomes

A patient's mental health prior to surgery can influence postoperative outcomes. Removal of the bladder, or radical cystectomy (RC), is an effective treatment for locally advanced bladder cancer, but complications occur in as many as 66% of patients.

18 Dec 2015

Central thalamus tunes the brain to different states of activity and arousal

Scientists showed that they could alter brain activity of rats and either wake them up or put them in an unconscious state by changing the firing rates of neurons in the central thalamus, a region known to regulate arousal.

18 Dec 2015

UT Southwestern researchers find potential mechanism to prevent epileptic seizures following TBI

UT Southwestern Medical Center researchers have found that halting production of new neurons in the brain following traumatic brain injury can help reduce resulting epileptic seizures, cognitive decline, and impaired memory.

18 Dec 2015

Research opens door to validation studies in multiple tumor types of liquid biopsy

Pancreatic cancer tumors spill their molecular secrets into the blood stream, shedding their complete DNA and RNA wrapped inside protective lipid particles that make them ripe for analysis with a liquid biopsy, researchers at The University of Texas MD Anderson Cancer Center report online at the Annals of Oncology.

18 Dec 2015

Toronto researchers reveal how opioids interfere with breathing mechanism

University of Toronto researchers on a quest to make opioid drugs less lethal have discovered a window of opportunity: a tiny channel in the brain where opioids interfere with the breathing mechanism.

18 Dec 2015

Family members of CUP patients at higher risk of developing CUP themselves

Cancer usually begins in one location and then spreads, but in 3 percent to 5 percent of cancer patients, the tissue where a cancer begins is unknown. In these individuals a cancer diagnosis is made because it has metastasized to other sites. Patients with these so-called "cancers of unknown primary," or CUP, have a very poor prognosis, with a median survival of three months.

18 Dec 2015

Harvard scientists link specific neurotransmitter in the brain with autistic behavior

In a discovery that could offer valuable new insights into understanding, diagnosing and even treating autism, Harvard scientists for the first time have linked a specific neurotransmitter in the brain with autistic behavior.

18 Dec 2015

Study explores link between obesity and breast-cancer related lymphedema

Each year, about 1.38 million women worldwide are diagnosed with breast cancer. Advances in treatment have facilitated a 90% five-year survival rate among those treated. Given the increased rate and length of survival following breast cancer, more and more survivors are facing life-time risk of developing late effects of cancer treatment that negatively impact long-term survival. In particular, Breast cancer-related lymphedema is one of the most distressing and feared late effects.

18 Dec 2015

Stem cell therapy not significantly better than conventional treatment for Crohn's disease

A clinical trial to test the effectiveness of a stem cell therapy among adults with difficult to treat Crohn's disease has found it is not significantly better than conventional treatment in producing sustained disease remission after one year.

18 Dec 2015

Medical Condition News

UB study traces how enigmatic molecules help cancer self-destruct

Kitov announces more data from Phase III trial on the favorable blood pressure effects of KIT-302

Chi-Med announces initiation of Phase III sulfatinib registration trial in patients with NETs in China

New test can help detect cancer and diabetes biomarkers in bloodstream

New nanotechnology approach could transform gliomas from death sentence into treatable condition

Novel drug candidate prevents nerve cell damage in mouse model of Parkinson's disease

Presence of mirror in dining rooms can reduce perceived tastiness of unhealthy food

Researchers elucidate structure of mTORC1 protein

AES Annual Meeting takes our understanding of epilepsy to next level

Case Western scientist to lead a pair of studies to develop more effective treatment for CF

Anti-aging Glycopeptide can improve efficacy of cell transplant treatments for diabetes patients

Patient's mental health prior to radical cystectomy can influence postoperative outcomes

Central thalamus tunes the brain to different states of activity and arousal

UT Southwestern researchers find potential mechanism to prevent epileptic seizures following TBI

Research opens door to validation studies in multiple tumor types of liquid biopsy

Toronto researchers reveal how opioids interfere with breathing mechanism

Family members of CUP patients at higher risk of developing CUP themselves

Harvard scientists link specific neurotransmitter in the brain with autistic behavior

Study explores link between obesity and breast-cancer related lymphedema

Stem cell therapy not significantly better than conventional treatment for Crohn's disease

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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