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Study finds no added benefit for insulin degludec and liraglutide in type 2 diabetes

The fixed-ratio combination of the two drugs insulin degludec and liraglutide (trade name: Xultophy) has been approved since September 2014 for adults with type 2 diabetes mellitus. It is given as an injection in addition to other blood-glucose lowering drugs when these alone or in combination with basal insulin are insufficient to lower blood glucose levels.

12 Aug 2015

Ion channel blockers prove useful in cancer therapy

Drugs called ion channel blockers, which are commonly used to treat cardiac, neurological, and psychiatric disorders, might prove useful in cancer therapy, according to research findings in fruit flies and mice by UC San Francisco scientists that led to unconventional treatment of a case of metastatic brain cancer.

12 Aug 2015

Gastric bypass surgery enhances energy expenditure

Gastric bypass surgery often leads to a sustained weight loss. Researchers at Sahlgrenska Academy have found part of the explanation: the operation enhances energy expenditure such that eating actually helps the person lose weight.

12 Aug 2015

Insulin pump users face less risk of dying from cardiovascular disease

People with type 1 diabetes who use insulin pump therapy face almost 50% less risk of dying from cardiovascular disease than those who take insulin by multiple daily injections. The British Medical Journal has published a study conducted at Sahlgrenska Academy.

12 Aug 2015

Only 1 in 4 patients with ESRD in Georgia referred for kidney transplant evaluation

Only about one in four patients with end-stage renal disease in Georgia were referred for kidney transplant evaluation within 1 year of starting dialysis between 2005 and 2011, although there was substantial variability in referral among dialysis facilities, according to a study in the August 11 issue of JAMA.

12 Aug 2015

Janssen signs license agreement with Alligator Bioscience for immuno-oncology antibody

Janssen Biotech, Inc., one of the Janssen pharmaceutical companies of Johnson & Johnson announced today an exclusive, worldwide license agreement with Alligator Bioscience AB for ADC-1013, an immuno-oncology agent currently in Phase 1 clinical studies.

12 Aug 2015

New study reveals role of hydrogen sulfide gas in autoimmune disease

The immune system not only responds to infections and other potentially problematic abnormalities in the body, it also contains a built-in brake in the form of regulatory T cells, or Tregs. Tregs ensure that inflammatory responses don't get out of hand and do damage. In autoimmune diseases, sometimes these Treg cells don't act as they should.

12 Aug 2015

Scientists identify molecular pathway that can contribute to vision loss in macular degeneration

Scientists have identified a pathway that leads to the formation of atypical blood vessels that can cause blindness in people with age-related macular degeneration.

12 Aug 2015

New study launched to find impact of vasculitis on employment, income

The Vasculitis Patient-Powered Research Network and the Vasculitis Clinical Research Consortium launched a study entitled "Impact of vasculitis on employment and income" or "VascWork." The purpose of this study is to learn about the impact of vasculitis on employment and income in patients with different systemic vasculitides.

12 Aug 2015

IQWiG dossier assessment finds no added benefit for vortioxetine in depression

Vortioxetine (trade name: Brintellix) has been approved since December 2013 for the treatment of depression in adults, but did not become actually available before May 2015. The German Institute for Quality and Efficiency in Health Care examined in a dossier assessment whether this drug offers an added benefit over the appropriate comparator therapy. Such an added benefit cannot be derived from the dossier because it contained no data evaluable for the assessment.

12 Aug 2015

Trans fats associated with greater risk of death, coronary heart disease

A study led by researchers at McMaster University has found that that trans fats are associated with greater risk of death and coronary heart disease, but saturated fats are not associated with an increased risk of death, heart disease, stroke, or Type 2 diabetes.

12 Aug 2015

New Johns Hopkins study shows hepatitis C infection may spell heart trouble

People infected with the hepatitis C virus are at risk for liver damage, but the results of a new Johns Hopkins study now show the infection may also spell heart trouble.

12 Aug 2015

Loss of critical receptor in the brain may be responsible for autism, schizophrenia

The loss of a critical receptor in a special class of inhibitory neurons in the brain may be responsible for neurodevelopmental disorders including autism and schizophrenia, according to new research by Salk scientists.

12 Aug 2015

Cost of radiation therapy varies widely among Medicare patients with cancer

Cost of radiation therapy among Medicare patients varied most widely because of factors unrelated to a patient or that person's cancer, report University of California, San Diego School of Medicine researchers in the Journal of Oncology Practice.

12 Aug 2015

Novel combination therapy effective at treating patients with skin metastases

In findings never before seen in melanoma, a novel combination therapy was found to be highly effective at treating patients with skin metastases, new research from UC Davis has shown.

12 Aug 2015

Orlando Health Heart Institute first in Central Florida to use CoreValve Evolut R System to replace heart valves

Leading edge heart valve technology is helping improve patient outcomes and giving doctors greater accuracy when implanting replacement valves. Interventional cardiologists and cardiovascular surgeons at the Orlando Health Heart Institute are the first in Central Florida to use the newly approved recapturable, self-expanding CoreValve Evolut R System.

12 Aug 2015

Breath analysis shows potential biomarkers for early-stage diagnosis of liver disease

A natural compound called limonene, which is found in oranges and lemons, could be indicative in early-stage diagnosis of liver disease, according to research published in the journal EBioMedicine by researchers in the Molecular Physics Group at the University of Birmingham.

12 Aug 2015

Aerobic exercise can help reduce excessive daytime sleepiness among depressed people

Aerobic exercise can help alleviate excessive daytime sleepiness among depressed individuals, researchers with UT Southwestern Medical Center's Center for Depression Research and Clinical Care have found.

12 Aug 2015

Mount Sinai launches clinical trial to test effectiveness of ticagrelor drug in treating coronary stent patients

The Icahn School of Medicine at Mount Sinai has launched an international clinical trial called TWILIGHT to test the safety and effectiveness of treating coronary stent patients with the anti-clotting medication ticagrelor alone, instead of combining it with aspirin, which is the current standard of care. Researchers will analyze the potential benefits of administering ticagrelor to reduce clotting while at the same time reducing the risk of bleeding associated with the use of both medications.

12 Aug 2015

Orthocell presents positive data for Ortho-ATI and Ortho-ACI in patients with damaged cartilage, tendon injuries

Regenerative medicine company Orthocell Limited is pleased to announce it has held its inaugural user group meeting in Sydney.

11 Aug 2015

Medical Condition News

Study finds no added benefit for insulin degludec and liraglutide in type 2 diabetes

Ion channel blockers prove useful in cancer therapy

Gastric bypass surgery enhances energy expenditure

Insulin pump users face less risk of dying from cardiovascular disease

Only 1 in 4 patients with ESRD in Georgia referred for kidney transplant evaluation

Janssen signs license agreement with Alligator Bioscience for immuno-oncology antibody

New study reveals role of hydrogen sulfide gas in autoimmune disease

Scientists identify molecular pathway that can contribute to vision loss in macular degeneration

New study launched to find impact of vasculitis on employment, income

IQWiG dossier assessment finds no added benefit for vortioxetine in depression

Trans fats associated with greater risk of death, coronary heart disease

New Johns Hopkins study shows hepatitis C infection may spell heart trouble

Loss of critical receptor in the brain may be responsible for autism, schizophrenia

Cost of radiation therapy varies widely among Medicare patients with cancer

Novel combination therapy effective at treating patients with skin metastases

Orlando Health Heart Institute first in Central Florida to use CoreValve Evolut R System to replace heart valves

Breath analysis shows potential biomarkers for early-stage diagnosis of liver disease

Aerobic exercise can help reduce excessive daytime sleepiness among depressed people

Mount Sinai launches clinical trial to test effectiveness of ticagrelor drug in treating coronary stent patients

Orthocell presents positive data for Ortho-ATI and Ortho-ACI in patients with damaged cartilage, tendon injuries

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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