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Johns Hopkins researchers discover role of TDP-43 protein in autopsy brain cells of patients with ALS

Autopsies of nearly every patient with the lethal neurodegenerative disorder amyotrophic lateral sclerosis (ALS), and many with frontotemporal dementia (FTD), show pathologists telltale clumps of a protein called TDP-43. Now, working with mouse and human cells, Johns Hopkins researchers report they have discovered the normal role of TDP-43 in cells and why its abnormal accumulation may cause disease.

7 Aug 2015

BMC partners with RIH, CVS to support pharmacy-based naloxone rescue kits to help combat opioid addiction, overdose

Boston Medical Center has received a $1.3 million grant from the Agency for Healthcare Research and Quality to support a demonstration project of pharmacy-based naloxone rescue kits to help reduce opioid addiction and overdose death in two New England States: Massachusetts and Rhode Island.

7 Aug 2015

Scientists publish new important clues about marrow fat

While most of us worry about the fat cells building up on the fleshy parts of our bodies, scientists have started to pay serious attention to another kind of fat cell deep inside our bones, in what's called the marrow.

7 Aug 2015

Researchers identify genome-organizing mechanism that transmits vital genetic materials during mitosis

Chromosomes are responsible for carrying our genes and essentially protecting the information that helps ensure normal, healthy growth, with vital instructions being passed on from cell to cell by a process known as mitosis. While this copying mechanism has been well understood for decades, scientists have been unable to describe exactly how genetic information is protected and properly segregated as mitosis is happening.

7 Aug 2015

Experts discuss ways to encourage appropriate use of epinephrine for all severe allergic reactions

There are times when emergency physicians can't be 100 percent sure a person is suffering from a severe allergic reaction, known as anaphylaxis, and may hesitate to use epinephrine. A new article says when in doubt - administer the epinephrine.

7 Aug 2015

New technology that tracks patients' eye movements may accurately measure brain injury

New technology that tracks the eye movements of patients may be a more accurate measure of brain injury than any other diagnostic measurements currently in use, according to a study recently published in the journal Concussion.

7 Aug 2015

Researcher reveals link between inflammatory response of neutrophils and spread of oral cancer

An abnormal immune response or "feedback loop" could very well be the underlying cause of metastases in oral cancers, according to Dr. Marco Magalhaes, Assistant Professor at the University of Toronto's Faculty of Dentistry and lead researcher in a study published in the journal Cancer Immunology Research.

7 Aug 2015

Experts explain how nutrition can influence inflammatory processes and help lower chronic diseases risk

An unresolved inflammatory response is likely to be involved from the early stages of disease development. Controlling inflammation is crucial to human health and a key future preventative and therapeutic target. In a recent ILSI Europe's article published in the British Journal of Nutrition, a coalition of experts explain how nutrition influences inflammatory processes and help reduce chronic diseases risk.

7 Aug 2015

Study sheds light on Avoidant/Restrictive Food Intake Disorder

When most people think of eating disorders, they think of anorexia nervosa and bulimia nervosa. But there's another condition that has nothing to do with concerns over weight, shape or body image, and it has been recognized in the latest edition of the Diagnostic and Statistical Manual of Mental Disorders, which doctors use to diagnose conditions.

7 Aug 2015

First self-assessment test developed to help clinicians diagnose autism in adults

Psychologists from Cardiff University have developed the first self-assessment test designed to help clinicians diagnose autism in adults.

7 Aug 2015

Secondhand exposure to asbestos could lead to mesothelioma

Mesothelioma.us, a free online resource that provides people with mesothelioma and their loved ones with in-depth and educational articles, information packets and more about the disease, has just posted a new article that discusses secondhand exposure to asbestos.

7 Aug 2015

Study may lead to effective antimicrobial treatment strategies for people with uncontrolled diabetes

Case Western Reserve scientists may have uncovered a molecular mechanism that sets into motion dangerous infection in the feet and hands often occurring with uncontrolled diabetes. It appears that high blood sugar unleashes destructive molecules that interfere with the body's natural infection-control defenses.

7 Aug 2015

Investigational topical drug shows promise in patients with early stage cutaneous T cell lymphoma

Results of a phase one trial show that an investigational topical drug, resiquimod gel, causes regression of both treated and untreated tumor lesions and may completely remove cancerous cells from both sites in patients with early stage cutaneous T cell lymphoma (CTCL) - a rare type of non-Hodgkin lymphoma that affects the skin.

7 Aug 2015

BIDMC scientists discover new vitamin B3 pathway that regulates liver metabolism

Researchers at Beth Israel Deaconess Medical Center have identified a new vitamin B3 pathway that regulates liver metabolism. The discovery provides an opportunity to pursue the development of novel drug therapies to address obesity, type 2 diabetes and related metabolic diseases.

7 Aug 2015

Adults exposed to childhood physical or sexual abuse at risk for ulcerative colitis

Adults who were exposed to childhood physical or sexual abuse were approximately twice as likely to have ulcerative colitis, according to a new nationally representative study from four researchers at the University of Toronto.

7 Aug 2015

USC researchers develop yeast model to study gene mutation that disrupts DNA duplication

Researchers at USC have developed a yeast model to study a gene mutation that disrupts the duplication of DNA, causing massive damage to a cell's chromosomes, while somehow allowing the cell to continue dividing.

7 Aug 2015

New fly model developed to study motor neuron degeneration

Researchers at the Babraham Institute and University of Massachusetts Medical School in the United States have developed a new model to study motor neuron degeneration and have used this to identify three genes involved in the neurodegeneration process. These findings could have relevance for understanding the progression of amyotrophic lateral sclerosis (ALS) and other forms of motor neuron disease (MND).

7 Aug 2015

Einstein and Montefiore researchers receive $1.2 million grant to advance spinal cord injury research

Researchers at Albert Einstein College of Medicine and Montefiore Health System have received a $1.2 million grant from New York State to advance their promising technology for treating paralysis and other effects of spinal cord injuries (SCI).

7 Aug 2015

FAU researchers identify endogenous process that controls reproduction of cardiac muscle cells

Heart failure is the most common cause of death worldwide. The main reason for this is that damage to the human heart causes cardiac muscle cells to die, which in turn leads to reduced heart function and death. However, this is not the case for zebrafish or amphibians. If their hearts become damaged and cardiac muscle cells die, their remaining cardiac muscle cells can reproduce, allowing the heart to regenerate.

7 Aug 2015

Newcastle University awarded £5M for drug development research

Cancer Research UK's Drug Discovery Committee has today (Friday) awarded Newcastle University's Northern Institute of Cancer Research £5M to bring more cancer drugs to clinical trials.

7 Aug 2015

Medical Condition News

Johns Hopkins researchers discover role of TDP-43 protein in autopsy brain cells of patients with ALS

BMC partners with RIH, CVS to support pharmacy-based naloxone rescue kits to help combat opioid addiction, overdose

Scientists publish new important clues about marrow fat

Researchers identify genome-organizing mechanism that transmits vital genetic materials during mitosis

Experts discuss ways to encourage appropriate use of epinephrine for all severe allergic reactions

New technology that tracks patients' eye movements may accurately measure brain injury

Researcher reveals link between inflammatory response of neutrophils and spread of oral cancer

Experts explain how nutrition can influence inflammatory processes and help lower chronic diseases risk

Study sheds light on Avoidant/Restrictive Food Intake Disorder

First self-assessment test developed to help clinicians diagnose autism in adults

Secondhand exposure to asbestos could lead to mesothelioma

Study may lead to effective antimicrobial treatment strategies for people with uncontrolled diabetes

Investigational topical drug shows promise in patients with early stage cutaneous T cell lymphoma

BIDMC scientists discover new vitamin B3 pathway that regulates liver metabolism

Adults exposed to childhood physical or sexual abuse at risk for ulcerative colitis

USC researchers develop yeast model to study gene mutation that disrupts DNA duplication

New fly model developed to study motor neuron degeneration

Einstein and Montefiore researchers receive $1.2 million grant to advance spinal cord injury research

FAU researchers identify endogenous process that controls reproduction of cardiac muscle cells

Newcastle University awarded £5M for drug development research

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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