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Severe OSA, excessive daytime sleepiness linked to increased risk of depression in men

Severe obstructive sleep apnea (OSA) and excessive daytime sleepiness are associated with an increased risk of depression in men, according to a new community-based study of Australian men, which was presented at the 2015 American Thoracic Society International Conference.

19 May 2015

Type 2 diabetes screening followed by treatment could reduce risk of cardiovascular disease, death

Screening to identify Type 2 diabetes followed by early treatment could result in substantial health benefits, according to new research published today in Diabetes Care that combined large scale clinical observations and innovative computer modelling.

19 May 2015

Study finds new colon cancer screening as promising alternative to colonoscopy for African Americans

In a first-of-its-kind clinical trial, physician-scientists at University Hospitals Case Medical Center Seidman Cancer Center and Case Western Reserve University School of Medicine found that a new non-invasive technology for colon cancer screening is a promising alternative to colonoscopy for African Americans.

19 May 2015

Two-drug combination improves lung function in some cystic fibrosis patients

The combination of two drugs — an investigational drug used in conjunction with an already FDA-approved medication — improved lung function in patients with one form of cystic fibrosis, according to two new studies.

19 May 2015

BioNTech, Genmab to jointly develop and commercialize immunomodulatory antibodies for cancer

BioNTech AG, a fully integrated biotechnology company developing truly personalized cancer immunotherapies, announces that it has signed an agreement with Genmab A/S to jointly research, develop and commercialize multiple bispecific antibodies for cancer immunotherapy using proprietary technologies from both companies: BioNTech's proprietary immunomodulatory antibodies and Genmab's DuoBody technology platform.

19 May 2015

Researchers uncover mechanism behind common mutation that helps cancer cells replicate limitlessly

More than 500,000 people in the United States die each year of cancer-related causes. Now, emerging research has identified the mechanism behind one of the most common mutations that help cancer cells replicate limitlessly.

19 May 2015

Leptin resistance not a possible cause of obesity, scientists find

For years, scientists have pointed to leptin resistance as a possible cause of obesity. Research led by investigators at the University of Cincinnati (UC) Metabolic Diseases Institute, however, found that leptin action isn't the culprit.

19 May 2015

UMD expert working to accelerate development of improved implantable cardiac devices

A University of Maryland expert in the model-based testing of embedded software is working to accelerate the development of improved implantable medical devices used in the treatment of heart disease.

19 May 2015

Blood-thinning treatment safe for patients with brain metastases

Cancer patients with brain metastases who develop blood clots may safely receive blood thinners without increased risk of dangerous bleeding, according to a study, published online today in Blood, the Journal of the American Society of Hematology.

19 May 2015

Post-operative atrial fibrillation can significantly increase risk of heart attack or stroke

As many as 12 percent of patients undergoing major, non-cardiac surgery experience an irregular heartbeat called atrial fibrillation.

19 May 2015

Researchers reveal molecular steps that allow pancreatic cancer to spread to the liver

An international team led by Weill Cornell Medical College investigators has illuminated the precise molecular steps that enable pancreatic cancer to spread to the liver -- the event that makes the most common form of the disease lethal. By understanding this process, investigators say their discovery can lead to targeted treatments that delay metastasis, and could offer clinicians a new biomarker to test for the earliest signs of pancreatic cancer.

19 May 2015

OSU researchers find promising approach to treating epithelial cancer

Researchers at Oregon State University are pursuing a new concept in treatment of epithelial cancer, especially head and neck cancer, by using two promising "analogs" of an old compound that was once studied as a potent anti-tumor agent, but long ago abandoned because it was too toxic.

19 May 2015

Researchers uncover major link between human body clock and immune system

An important link between the human body clock and the immune system has relevance for better understanding inflammatory and infectious diseases, discovered collaborators at the Perelman School of Medicine at the University of Pennsylvania and Trinity College, Dublin.

19 May 2015

Adolescents with sleep issues more likely to use alcohol, marijuana

Adolescents who sleep less or stay up later are significantly more likely to have used alcohol and marijuana over the past month when compared to their peers who report better sleep patterns, according to a new RAND Corporation study.

19 May 2015

Simple blood test can predict evidence of TBI on radiographic imaging, injury severity

New study results show that a simple blood test to measure brain-specific proteins released after a person suffers a traumatic brain injury (TBI) can reliably predict both evidence of TBI on radiographic imaging and injury severity.

19 May 2015

Study quantifies different mutational profiles of tumour cell clusters in patients with bowel cancer

Bowel cancer is often driven by mutations in one of several different genes, and a patient can have a cancer with a different genetic make-up to another patient's cancer. Identifying the molecular alterations involved in each patient's cancer enables doctors to choose drugs that best target specific alterations.

19 May 2015

Experts team up to tackle a growing challenge to nuclear test monitoring

The world's experts in nuclear explosion monitoring teamed up with pharmaceutical producers from across the globe in Brussels, Belgium, from 12 to 14 May 2015, to address a growing challenge to nuclear test monitoring.

19 May 2015

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Alnylam Pharmaceuticals, Inc. has announced that it has filed a Clinical Trial Application (CTA) with the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) to initiate a Phase 1/2 clinical trial with ALN-AAT, a subcutaneously administered investigational RNAi therapeutic targeting alpha-1 antitrypsin (AAT) for the treatment of AAT deficiency-associated liver disease (alpha-1 liver disease).

19 May 2015

Toxin pneumolysin causes progressive and fatal heart complications

Streptococcus pneumoniae is a major human pathogen and is known to be associated with increased risk of fatal heart complications including heart failure and heart attacks.

19 May 2015

Multi-center study shows WATS3D biopsy increases detection of esophageal pre-cancer by 60% following endoscopic ablation of Barrett’s Esophagus

CDx Diagnostics announced today new clinical data from a multi-center study demonstrating the utility of the WATS3D biopsy for post-ablation surveillance of Barrett’s esophagus and esophageal dysplasia...

18 May 2015

Medical Condition News

Severe OSA, excessive daytime sleepiness linked to increased risk of depression in men

Type 2 diabetes screening followed by treatment could reduce risk of cardiovascular disease, death

Study finds new colon cancer screening as promising alternative to colonoscopy for African Americans

Two-drug combination improves lung function in some cystic fibrosis patients

BioNTech, Genmab to jointly develop and commercialize immunomodulatory antibodies for cancer

Researchers uncover mechanism behind common mutation that helps cancer cells replicate limitlessly

Leptin resistance not a possible cause of obesity, scientists find

UMD expert working to accelerate development of improved implantable cardiac devices

Blood-thinning treatment safe for patients with brain metastases

Post-operative atrial fibrillation can significantly increase risk of heart attack or stroke

Researchers reveal molecular steps that allow pancreatic cancer to spread to the liver

OSU researchers find promising approach to treating epithelial cancer

Researchers uncover major link between human body clock and immune system

Adolescents with sleep issues more likely to use alcohol, marijuana

Simple blood test can predict evidence of TBI on radiographic imaging, injury severity

Study quantifies different mutational profiles of tumour cell clusters in patients with bowel cancer

Experts team up to tackle a growing challenge to nuclear test monitoring

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Toxin pneumolysin causes progressive and fatal heart complications

Multi-center study shows WATS3D biopsy increases detection of esophageal pre-cancer by 60% following endoscopic ablation of Barrett’s Esophagus

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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