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Researchers identify three genes involved in choroid plexus carcinoma

Researchers have identified three genes that play a pivotal role in the brain tumor choroid plexus carcinoma (CPC), a discovery that lays the groundwork for more effective treatment of this rare, often fatal cancer. St. Jude Children's Research Hospital scientists led the study, which appears today in the journal Cancer Cell.

12 May 2015

MD Anderson researchers discover link between telomere degeneration and MDS

A study revealing fresh insight about chromosome "tails" called telomeres may provide scientists with a new way to look at developing treatments or even preventing a group of blood cell disorders known as myelodysplastic syndromes (MDS).

12 May 2015

New study reveals genetic causes of rare syndrome that manifests as high blood pressure

The culmination of two decades of research, a new study reveals the genetic causes of a curious, rare syndrome that manifests as hypertension (high blood pressure) accompanied by short fingers (brachydactyly type E).

12 May 2015

Study: Disrupting cancer pathway could extend benefits of new immunity-boosting drugs

Understanding how to overrule a signaling pathway that can cause treatments to fail in metastatic melanoma patients should help physicians extend the benefits of recently approved immunity-boosting drugs known as checkpoint inhibitors to more patients.

12 May 2015

New Johns Hopkins-led research suggests risk factors for developing acute kidney injury

Physicians treating hospitalized patients for conditions unrelated to the kidneys should pay close attention to common blood and urine tests for kidney function in order to prevent incidental injury to the organs that help cleanse the body of toxins, new Johns Hopkins Bloomberg School of Public Health-led research suggests.

12 May 2015

Study finds extremely high levels of cardiovascular risk factors in people with psychosis

Extremely high levels of cardiovascular risk factors have been found in people with established psychosis, with central obesity evident in over 80 per cent of participants, in a study by researchers from the NIHR Biomedical Research Centre at the South London and Maudsley NHS Foundation Trust and King's College London.

12 May 2015

New study finds that some immigrants, refugees in Ontario at higher risk of psychotic disorders

Immigrants from the Caribbean and Bermuda, as well as refugees from East Africa and South Asia, have a 1.5 to 2 times higher risk of psychotic disorders compared to the general population of Ontario, Canada, according to a new study by researchers at the Institute for Clinical Evaluative Sciences and the Centre for Addiction and Mental Health.

12 May 2015

Merck KGaA, Darmstadt, Germany granted FDA Fast Track designation for development of evofosfamide

Merck KGaA, Darmstadt, Germany, a leading company for innovative and top-quality high-tech products in healthcare, life science and performance materials today announced that the U.S. Food and Drug Administration has granted Fast Track designation for the development of evofosfamide (previously known as TH-302), administered in combination with gemcitabine, for the treatment of previously untreated patients with metastatic or locally advanced unresectable pancreatic cancer.

12 May 2015

Special JHTR issue highlights ongoing CDC efforts to reduce population impact of TBI

Ongoing efforts by the Centers for Disease Control and Prevention to reduce the population impact of traumatic brain injury (TBI) are documented in the May/June issue of The Journal of Head Trauma Rehabilitation, official journal of the Brain Injury Association of America.

12 May 2015

UC Irvine study opens door to novel treatments for people with retinal damage

Driving down a dimly lit road at midnight can tax even those with 20/20 vision, but according to a recent UC Irvine study, the brain processes the experience no differently than if it were noon. The same study also reveals how quickly the brain adapts to vision loss, contradicting earlier research and opening the door to novel treatments.

12 May 2015

New study finds link between father's age at birth and child's risk of blood cancer as an adult

A new study links a father's age at birth to the risk that his child will develop blood and immune system cancers as an adult, particularly for only children. The study, which appears in the American Journal of Epidemiology, found no association between having an older mother and these cancers.

12 May 2015

Discovery paves way for developing treatments for people addicted to cocaine, amphetamines

In a major advance in the field of neuropsychiatry, researchers in the Vollum Institute at Oregon Health & Science University have illuminated how cocaine and amphetamines disrupt the normal functioning of the dopamine transporter in the brain.

12 May 2015

OSU scientists develop more accurate method to evaluate cancer risk of pollutants

Scientists at Oregon State University have developed a faster, more accurate method to assess cancer risk from certain common environmental pollutants.

12 May 2015

Study highlights potential new targets for development of novel cancer therapy

An international consortium of scientists led by a group from the University of Leicester has announced a new advance in understanding the mechanisms of cancer and how to target it more effectively with new treatments.

12 May 2015

New method may help determine potential indicator of stress, neurological disorders

A research collaboration between the universities of Oslo and Aarhus has resulted in the development of a new method with diagnostic potential. The new method that combines phase extraction with an enzymatic reaction may eventually be used for an improved and faster screening analysis of isatin as a potential indicator of stress and neurological disorders.

12 May 2015

Myopia on the rise across Europe, new study finds

Myopia or short-sightedness is becoming more common across Europe, according to a new study led by King's College London. The meta-analysis of findings from 15 studies by the European Eye Epidemiology Consortium found that around a quarter of the European population is short-sighted but it is nearly twice as common in younger people, with almost half (47 per cent) of the group aged between 25 and 29 years affected.

12 May 2015

Scientists find smooth muscle cells as major contributing factor to vascular stiffness

Increased vascular stiffness has been identified as an important part of hypertension in aging adults. Previous studies of aortic stiffness have focused on changes in structural proteins that alter the properties of vascular walls causing them to become rigid.

11 May 2015

Scientists identify gene that causes hereditary hypertension and brachydactyly type E

Individuals with this altered gene have hereditary hypertension (high blood pressure) and at the same time a skeletal malformation called brachydactyly type E, which is characterized by unusually short fingers and toes. The effect on blood pressure is so serious that -- if left untreated -- it most often leads to death before age fifty.

11 May 2015

Walnut-enriched diet may slow colorectal tumor growth

A new animal study from Beth Israel Deaconess Medical Center, Harvard Medical School, led by Dr. Christos Mantzoros, indicates that a diet containing walnuts may slow colorectal tumor growth by causing beneficial changes in cancer genes.

11 May 2015

Panacea Pharmaceuticals selects Goodwin to complete novel vaccine Fill / Finish project

Goodwin Biotechnology, Inc., a biological Contract Development and Manufacturing Organization that specializes in bioprocess development and GMP manufacturing of biopharmaceuticals utilizing Mammalian Cell Culture expression systems and Bioconjugation technologies, was selected by Panacea Pharmaceuticals, Inc. to complete a novel Fill / Finish project, as well as Quality Control release and stability testing for a therapeutic, nanoparticle cancer vaccine based on the Human Aspartyl (Asparaginyl) β-Hydroxylase (HAAH) tumor-specific protein to support Phase I clinical trials in patients with various solid tumor cancers.

11 May 2015

Medical Condition News

Researchers identify three genes involved in choroid plexus carcinoma

MD Anderson researchers discover link between telomere degeneration and MDS

New study reveals genetic causes of rare syndrome that manifests as high blood pressure

Study: Disrupting cancer pathway could extend benefits of new immunity-boosting drugs

New Johns Hopkins-led research suggests risk factors for developing acute kidney injury

Study finds extremely high levels of cardiovascular risk factors in people with psychosis

New study finds that some immigrants, refugees in Ontario at higher risk of psychotic disorders

Merck KGaA, Darmstadt, Germany granted FDA Fast Track designation for development of evofosfamide

Special JHTR issue highlights ongoing CDC efforts to reduce population impact of TBI

UC Irvine study opens door to novel treatments for people with retinal damage

New study finds link between father's age at birth and child's risk of blood cancer as an adult

Discovery paves way for developing treatments for people addicted to cocaine, amphetamines

OSU scientists develop more accurate method to evaluate cancer risk of pollutants

Study highlights potential new targets for development of novel cancer therapy

New method may help determine potential indicator of stress, neurological disorders

Myopia on the rise across Europe, new study finds

Scientists find smooth muscle cells as major contributing factor to vascular stiffness

Scientists identify gene that causes hereditary hypertension and brachydactyly type E

Walnut-enriched diet may slow colorectal tumor growth

Panacea Pharmaceuticals selects Goodwin to complete novel vaccine Fill / Finish project

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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