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Overview of Blueprint Medicines' kinase drug discovery strategy published in JCI

Blueprint Medicines today announced that the Journal of Clinical Investigation published an overview of the Company's kinase drug discovery and development strategy. The publication underscores Blueprint Medicines' focus on identifying novel genomically defined disease drivers and the use of novel chemistry from its proprietary compound library to craft highly selective kinase inhibitors for new and difficult-to-drug kinase targets.

11 May 2015

Boehringer Ingelheim, Sutter Health announce health care innovation collaboration

Boehringer Ingelheim, a family-owned biopharmaceutical company, and Sutter Health, a not-for-profit health system in Northern California, today announced the start of a five-year research and health care innovation collaboration, which will explore and test the value of digital health solutions, mobile technologies, and insights from advanced data analytics in the delivery of health care.

11 May 2015

MJFF announces acquisition of parkin research tools from Imago Pharmaceuticals

The Michael J. Fox Foundation for Parkinson's Research announces the acquisition of a library of research tools around the parkin protein from Imago Pharmaceuticals. The Foundation believes these tools — cell lines, plasmids, compounds and more — will accelerate biological study and drug development against this promising disease-modification target.

11 May 2015

Can-Fite receives EMA clearance to begin CF102 Phase II trial for treatment of HCC patients in Europe

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs being developed to treat inflammatory diseases, cancer and sexual dysfunction, today announced it recently received clearance from the European Medicines Agency to commence dosing patients in Europe in its global Phase II trial for CF102 in the treatment of hepatocellular carcinoma (HCC), the most common form of liver cancer.

11 May 2015

Debiotech agrees to acquire exclusive rights on iSense CGM technology for use with patch pumps

Debiotech of Switzerland and iSense CGM, Inc. of the US, announced today having entered into an Agreement under which Debiotech has the option to acquire the exclusive rights on the iSense CGM product and technology for use with patch pumps for diabetes therapy. Financial terms and conditions of the Agreement are not disclosed.

11 May 2015

New scanning methods could help predict people vulnerable to schizophrenia

New scanning methods which map the wiring of the brain could provide a valuable new tool to predict people at risk of schizophrenia, according to a new study.

11 May 2015

Mixture of two anti-EGFR antibodies clinically active in treatment-resistant colorectal cancer

Patients with advanced colorectal tumors without mutations in the RAS genes derive substantial benefit from anti-EGFR therapies; however, the disease eventually progresses, leaving these patients with few alternative therapeutic options.

11 May 2015

Research findings could lead to new targeted treatments for aggressive subtype of lymphoma

An international team of researchers, including Lukas Kenner from the Clinical Department of Pathology at MedUni Vienna, has discovered a specific combination of mutations and new gene fusions, which are heavily implicated in tumour growth in patients with a particularly aggressive subtype of lymphoma (ALCL).

11 May 2015

Small ion pump gives new hope for severe nerve pain sufferers

A small ion pump in organic electronics is giving new hope to people suffering from severe nerve pain. Researchers at Swedish Linköping University and the Karolinska Institute are the first in the world with technology that can stop pain impulses in living, freely moving rats using the body's own pain relief signals.

11 May 2015

Global survey finds gap in physicians' understanding on impact of lupus on patients' lives

As many people in the lupus community prepare to come together in support of World Lupus Day (May 10), a global survey shows that systemic lupus erythematosus (SLE) patients have difficulty describing their symptoms to their physicians, which leads to a gap in physicians understanding the full impact the illness has on patients' lives.

11 May 2015

Roche announces FDA approval of cobas KRAS Mutation Test for diagnostic use

Roche today announced that the U.S. Food and Drug Administration has approved the cobas KRAS Mutation Test for diagnostic use. The real-time PCR test is designed to identify KRAS mutations in tumor samples from metastatic colorectal cancer (mCRC) patients and aid clinicians in determining a therapeutic path for them.

11 May 2015

Obesity rates elevated in childhood cancer survivors who are exposed to certain treatments

Individuals who had cancer as a child may be at increased risk of being obese due to the therapies they received during their youth. The finding comes from a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. The study's results suggest the need for effective counseling and weight loss interventions for certain childhood cancer survivors.

11 May 2015

Non-suicidal self-injury common among Iraq and Afghanistan veterans

Non-suicidal self-injury--that is, purposefully hurting oneself without conscious suicidal intent--is relatively common among Iraq and Afghanistan veterans, according to a study published online April 1, 2015, in Psychiatry Research.

10 May 2015

Study finds link between PTSD and accelerated aging

In recent years, public health concerns about post-traumatic stress disorder (PTSD) have risen significantly, driven in part by affected military veterans returning from conflicts in the Middle East and elsewhere. PTSD is associated with number of psychological maladies, among them chronic depression, anger, insomnia, eating disorders and substance abuse.

10 May 2015

Researchers identify promising combination strategy for treating glioblastomas

Therapies that specifically target mutations in a person's cancer have been much-heralded in recent years, yet cancer cells often find a way around them. To address this, researchers at University of California, San Diego School of Medicine and Moores Cancer Center identified a promising combinatorial approach to treating glioblastomas, the most common form of primary brain cancer.

10 May 2015

International study finds widespread homophobia in UK sport

The world's first international study on homophobia in sport, "Out on the Fields," has found widespread homophobia in UK sport, prompting calls for a zero tolerance approach towards discrimination and better training for coaches, teachers and officials.

9 May 2015

New edition of WHO Essential Medicines List includes new treatments for hepatitis C, cancers and multi-drug TB

WHO today published the new edition of its Model List of Essential Medicines which includes ground-breaking new treatments for hepatitis C, a variety of cancers (including breast cancer and leukaemia) and multi-drug resistant tuberculosis (TB), among others. The move opens the way to improve access to innovative medicines that show clear clinical benefits and could have enormous public health impact globally.

8 May 2015

Danish researchers discover way to map more than one protein at a time

Danish researchers at the University of Copenhagen have discovered how to map more than one protein at a time, when proteins repair damaged DNA. It is a discovery that will help accelerate the process of developing better and gentler cancer treatments.

8 May 2015

Full body dermatological scanner could help diagnose skin conditions in the future

Melanoma is aggressive and life-threatening. If it is not detected early, the prospects of recovery drop. Screening is complicated, though. Together with several project partners, Fraunhofer researchers have developed an assistance system that helps dermatologists with diagnosis.

8 May 2015

Study: Walking and cycling to work could help reduce BMI

Leaving your car at home could help shed pounds - according to new research from the University of East Anglia and the Centre for Diet and Activity Research. New research shows that making a change from driving to work to using public transport, cycling or walking could help reduce BMI over two years.

8 May 2015

Medical Condition News

Overview of Blueprint Medicines' kinase drug discovery strategy published in JCI

Boehringer Ingelheim, Sutter Health announce health care innovation collaboration

MJFF announces acquisition of parkin research tools from Imago Pharmaceuticals

Can-Fite receives EMA clearance to begin CF102 Phase II trial for treatment of HCC patients in Europe

Debiotech agrees to acquire exclusive rights on iSense CGM technology for use with patch pumps

New scanning methods could help predict people vulnerable to schizophrenia

Mixture of two anti-EGFR antibodies clinically active in treatment-resistant colorectal cancer

Research findings could lead to new targeted treatments for aggressive subtype of lymphoma

Small ion pump gives new hope for severe nerve pain sufferers

Global survey finds gap in physicians' understanding on impact of lupus on patients' lives

Roche announces FDA approval of cobas KRAS Mutation Test for diagnostic use

Obesity rates elevated in childhood cancer survivors who are exposed to certain treatments

Non-suicidal self-injury common among Iraq and Afghanistan veterans

Study finds link between PTSD and accelerated aging

Researchers identify promising combination strategy for treating glioblastomas

International study finds widespread homophobia in UK sport

New edition of WHO Essential Medicines List includes new treatments for hepatitis C, cancers and multi-drug TB

Danish researchers discover way to map more than one protein at a time

Full body dermatological scanner could help diagnose skin conditions in the future

Study: Walking and cycling to work could help reduce BMI

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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