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Data from pacritinib Phase 3 PERSIST-1 trial in patients with myelofibrosis to be highlighted at ASCO

CTI BioPharma Corp. and Baxter International Inc. today announced that data from the randomized Phase 3 PERSIST-1 trial evaluating the investigational agent pacritinib in patients with myelofibrosis will be highlighted in a late-breaking oral presentation at the upcoming American Society of Clinical Oncology 2015 Meeting (May 29-June 2, 2015 in Chicago, Ill).

From Baxter International Inc. 22 Apr 2015

New treatment shows promise in easing symptoms of Parkinson's disease

To date, a cure for Parkinson's disease remains elusive for the more than 50,000 Americans diagnosed yearly, despite decades of intensive study. But a newly approved treatment that might help ease the symptoms of Parkinson's has shown remarkable promise.

22 Apr 2015

Discovery unveils novel drug targets to halt peripheral neuropathies, neurodegenerative disorders

New research highlights how nerves - whether harmed by disease or traumatic injury - start to die, a discovery that unveils novel targets for developing drugs to slow or halt peripheral neuropathies and devastating neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (ALS).

22 Apr 2015

Honokiol extract holds promise as adjunct treatment for bladder and kidney cancers

The botanical extract honokiol, a biologically active molecule isolated from the bark of Magnolia spp., holds promise as an adjunct treatment for aggressive bladder and kidney cancers, as reported in two new studies. New research on honokiol in bladder cancer was presented at the American Association for Cancer Research Annual Meeting 2015.

22 Apr 2015

Incidence of potentially life-threatening diabetes complication increasing among youth in Colorado

The incidence of a potentially life-threatening complication of diabetes, diabetic ketoacidosis, in youth in Colorado at the time of diagnosis of type 1 diabetes increased by 55 percent between 1998 and 2012, suggesting a growing number of youth may experience delays in diagnosis and treatment, according to a study in the April 21 issue of JAMA, a theme issue on child health.

22 Apr 2015

Tumor necrosis factor helps regulate sensitivity to bitter taste

New research from the Monell Center reveals that tumor necrosis factor (TNF), an immune system regulatory protein that promotes inflammation, also helps regulate sensitivity to bitter taste. The finding may provide a mechanism to explain the taste system abnormalities and decreased food intake that can be associated with infections, autoimmune disorders, and chronic inflammatory diseases.

22 Apr 2015

Unique approach to academia-industry training could help improve proton therapy treatment

Improving proton therapy for cancer treatment is one of the many advances in accelerator science that have been fast-tracked by a unique approach to academia-industry training, led by the Cockcroft Institute. The two programmes, which have produced 42 highly valued research fellows, are drawing to a conclusion and industry partners are warning of a skills chasm in the very near future unless further training is prioritised.

22 Apr 2015

Manchester scientists make key finding that could help deliver early test for kidney disease

Scientists at The University of Manchester have made an important finding that could help develop an early test for kidney disease.

22 Apr 2015

Scientists identify protein that could help tame severe inflammation

Researchers have identified a protein that offers a new focus for developing targeted therapies to tame the severe inflammation associated with multiple sclerosis (MS), colitis and other autoimmune disorders.

22 Apr 2015

James Shapiro's latest research could soon mark new standard for diabetes treatment

James Shapiro, one of the world's leading experts in emerging treatments of diabetes, can't help but be excited about his latest research. The results he says, could soon mark a new standard for treatment--not only in diabetes, but in several other diseases as well.

22 Apr 2015

Researchers uncover methylated DNA markers that may lead to noninvasive cancer screening

A team of Mayo Clinic researchers has succeeded in identifying the source of cancer in patients' gastrointestinal tracts by analyzing DNA markers from tumors. The results open the possibility that doctors could one day be able to screen for cancer anywhere in the body with a noninvasive blood test or stool sample.

22 Apr 2015

IUPUI researcher awarded NIH grant to study neuroscience underlying obstructive sleep apnea

Sleep apnea affects an estimated 25 million adults in the United States and is associated with increased risk of hypertension, stroke, health attack and heart failure.

22 Apr 2015

New research examines what happens when MS patients discontinue their medication

New research led by NYU Langone Medical Center examines what happens when a patient with multiple sclerosis (MS) who is clinically stable stops taking their medication.

22 Apr 2015

New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

Individuals with type 2 diabetes, who are resistant to insulin, have an excess blood glucose level, which they are now trying to reduce using a new class of diabetes drugs known as the gliflozins.

22 Apr 2015

U of T studies find harmful vehicle emissions spreading farther than thought across Canadian cities

A trio of recently published studies from a team of University of Toronto engineers has found that air pollution could be spreading up to three times farther than thought--contributing to varying levels of air quality across cities.

22 Apr 2015

EuroPRevent congress to focus on cardiovascular disease

While death rates from heart disease in Europe have more than halved in many countries and in most population groups since the early 1980s, heart disease remains by far the leading cause of death.

22 Apr 2015

Astellas, Potenza collaborate to develop immuno-oncology therapeutics for patients with certain cancers

Astellas Pharma Inc. and Potenza Therapeutics, Inc., a biotechnology company developing a portfolio of immuno-oncology programs, today announced an exclusive research and development collaboration.

22 Apr 2015

University of Birmingham researchers identify new way to tackle chronic diseases

Researchers from the University of Birmingham have identified an important new way in which our immune systems are regulated, and hope that understanding it will help tackle the debilitating effects of type 1 diabetes, rheumatoid arthritis and other serious diseases.

22 Apr 2015

Cardio3 BioSciences reports absence of short term adverse events in first patient following NKG2D CAR T-cell infusion

Cardio3 BioSciences, soon to be renamed Celyad, a leader in engineered cell-therapy treatments today announced the infusion of the first patient enrolled in the Company’s Phase I clinical trial evaluating the safety and feasibility of its NKG2D CAR T-cell therapy, in cancer patients suffering from acute myeloid leukemia (AML) or multiple myeloma (MM).

22 Apr 2015

Upsher-Smith presents favorable data from PREVAIL OLE study of Qudexy XR capsules

Upsher-Smith Laboratories, Inc. presented data from a 52-week, open-label extension study (PREVAIL OLE) showing that Qudexy XR (topiramate) extended-release capsules offered a long-term adjunctive treatment option with a favorable tolerability profile for a high proportion of patients with refractory partial-onset seizures (POS).

21 Apr 2015

Medical Condition News

Data from pacritinib Phase 3 PERSIST-1 trial in patients with myelofibrosis to be highlighted at ASCO

New treatment shows promise in easing symptoms of Parkinson's disease

Discovery unveils novel drug targets to halt peripheral neuropathies, neurodegenerative disorders

Honokiol extract holds promise as adjunct treatment for bladder and kidney cancers

Incidence of potentially life-threatening diabetes complication increasing among youth in Colorado

Tumor necrosis factor helps regulate sensitivity to bitter taste

Unique approach to academia-industry training could help improve proton therapy treatment

Manchester scientists make key finding that could help deliver early test for kidney disease

Scientists identify protein that could help tame severe inflammation

James Shapiro's latest research could soon mark new standard for diabetes treatment

Researchers uncover methylated DNA markers that may lead to noninvasive cancer screening

IUPUI researcher awarded NIH grant to study neuroscience underlying obstructive sleep apnea

New research examines what happens when MS patients discontinue their medication

New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

U of T studies find harmful vehicle emissions spreading farther than thought across Canadian cities

EuroPRevent congress to focus on cardiovascular disease

Astellas, Potenza collaborate to develop immuno-oncology therapeutics for patients with certain cancers

University of Birmingham researchers identify new way to tackle chronic diseases

Cardio3 BioSciences reports absence of short term adverse events in first patient following NKG2D CAR T-cell infusion

Upsher-Smith presents favorable data from PREVAIL OLE study of Qudexy XR capsules

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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