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Fat cell transplantation benefits systemic sclerosis patients with non-healing digital ulcers

Digital ulcers (DUs) are a frequent, painful, and quality of life altering complication for patients with systemic sclerosis (SSc), a connective tissue disease causing a progressive loss of small blood vessels and resulting changes in organs and tissues. DUs on the fingertips of SSc patients are slow to heal, if they heal at all, as many are unresponsive to any therapies.

26 Feb 2015

Novel technology could improve diagnosis of peripheral arterial disease

Approximately 8 to 12 million people in the United States alone are suffering from peripheral arterial disease (PAD), a common vascular problem that is caused by narrowing of the arteries as a result of plaque buildup. The plaque accumulation leads to an insufficient blood flow to the body's extremities and increases a person's risk for heart attack and stroke by up to six times. PAD is also one of the most serious complications of diabetes.

26 Feb 2015

Intrinsically disordered proteins have ability to alter their configuration

Like the shape-shifting robots of "Transformers" fame, a unique class of proteins in the human body also has the ability to alter their configuration. These so-named intrinsically disordered proteins (IDPs) lack a fixed or ordered three-dimensional structure, which can be influenced by exposure to various chemicals and cellular modifications.

26 Feb 2015

U of T Scarborough professor develops new compound that can lead to cheaper anti-cancer drugs

A new compound developed at the University of Toronto Scarborough could play an important role in developing cheaper anti-cancer drugs.

26 Feb 2015

Scientists identify novel gene that affects brain function

U.S. and Australian scientists have found the mechanism a novel gene uses to affect brain function and elicit behavior related to neuropsychiatric disease.

26 Feb 2015

Cherenkov Effect can help make radiation therapy safer, more effective for patients with cancer

The characteristic blue glow from a nuclear reactor is present in radiation therapy, too. Investigators from Dartmouth's Norris Cotton Cancer Center, led by Brian W. Pogue, PhD, and PhD candidates Adam K. Glaser and Rongxiao Zhang, published in Physics in Medicine and Biology how the complex parts of the blue light known as the Cherenkov Effect can be measured and used in dosimetry to make therapies safer and more effective.

26 Feb 2015

Scientists discover DNA vaccine that alleviates chronic inflammation in the body

An international team of scientists including CureLab Oncology, Inc. (Boston), University of Camerino (Italy), and Boston University have serendipitously discovered a DNA vaccine, which systemically alleviates chronic inflammation in the body. Since osteoporosis is an inflammatory disease, preventive and therapeutic effects of the new vaccine were demonstrated on mouse models with osteoporosis.

26 Feb 2015

Prexton closes €8.7 million in Series A financing to develop treatments for Parkinson’s disease

Prexton Therapeutics, a biopharmaceutical company developing novel therapeutic compounds for the treatment of CNS conditions including Parkinson’s disease, today announces the closing of a Series A financing of €8.7 million ($10 million) co-led by Sunstone Capital and Ysios Capital.

26 Feb 2015

Tolero's alvocidib receives EMA orphan drug designation for treatment of AML patients

Tolero Pharmaceuticals, Inc., a clinical-stage company developing treatments for serious hematological diseases, today announced that the European Medicines Agency has granted orphan drug designation for alvocidib for the treatment of patients with acute myeloid leukemia (AML).

26 Feb 2015

Remsima (infliximab) now available in Europe for treatment of autoimmune diseases

Celltrion Healthcare has today announced the launch of Remsima (infliximab) in 12 European markets: Austria, Belgium, Denmark, France, Germany, Greece, Italy, Luxembourg, the Netherlands, Spain, Sweden and the UK.

26 Feb 2015

Sanofi announces FDA approval of Toujeo insulin to improve glycemic control in people with diabetes

Sanofi announced today that the U.S. Food and Drug Administration approved Toujeo (insulin glargine [rDNA origin] injection, 300 U/mL), a once-daily long-acting basal insulin, to improve glycemic control in adults living with type 1 and type 2 diabetes. Toujeo is expected to be available in the U.S. at the beginning of Q2 2015.

26 Feb 2015

New online and telephone service launched to help people take part in dementia research

A NEW nationwide online and telephone service helping people take part in dementia research studies has been launched - the first of its kind in the UK.

26 Feb 2015

Psoriasis management: an interview with Dr Sandy McBride

A major challenge around treating psoriasis is communication - psoriasis can flare and resolve in between appointments so it can be difficult to express and describe the life impact of these flares and recall possible triggers and response to treatments. People with psoriasis can also find it very difficult to talk about their emotions – something known as alexithymia – again making it difficult for clinicians to fully appreciate the impact of psoriasis.

25 Feb 2015

Monell Center to promote Anosmia Awareness Day with new educational outreach initiatives

The Monell Center announces three new educational outreach initiatives to promote Anosmia Awareness Day, which takes place on February 27. Each was designed to increase awareness and increase the limited information currently available about anosmia, the loss of our sense of smell, which affects over six million Americans and many millions more worldwide.

25 Feb 2015

Scientists use graphene to target, neutralise cancer stem cells

University of Manchester scientists have used graphene to target and neutralise cancer stem cells while not harming other cells.

25 Feb 2015

New, first-of-its-kind app helps patients with chronic pain track opioid use

A new, first-of-its-kind app has launched to help patients suffering from chronic pain track their opioid use and measure pain levels to assist with the safe use of opioids.

25 Feb 2015

Smokers who quit early does not qualify for lung cancer screening, say Mayo Clinic researchers

A decline in smoking rates may mean that many people who could have benefited from early detection of lung cancer are dying because they don't qualify for low-dose CT scans, according to a group of Mayo Clinic researchers.

25 Feb 2015

Sorafenib, sunitinib provide no benefit to patients with locally advanced kidney cancer

Findings from a federally funded study suggest that patients with locally advanced kidney cancer should not be treated with either adjuvant (post-surgery) sorafenib or sunitinib. The average period to disease recurrence was similar between those who received sorafenib or sunitinib after surgery (5.6 years) and those treated with placebo (5.7 years).

25 Feb 2015

Researchers develop revolutionary approach to treat drug-resistant tumors

In greater than 90 percent of cases in which treatment for metastatic cancer fails, the reason is that the cancer is resistant to the drugs being used. To treat drug-resistant tumors, doctors typically use multiple drugs simultaneously, a practice called combination therapy.

25 Feb 2015

New TAU study may offer hope to people diagnosed with Glioblastoma multiforme

There are no effective available treatments for sufferers of Glioblastoma multiforme (GBM), the most aggressive and devastating form of brain tumor. The disease, always fatal, has a survival rate of only 6-18 months.

25 Feb 2015

Medical Condition News

Fat cell transplantation benefits systemic sclerosis patients with non-healing digital ulcers

Novel technology could improve diagnosis of peripheral arterial disease

Intrinsically disordered proteins have ability to alter their configuration

U of T Scarborough professor develops new compound that can lead to cheaper anti-cancer drugs

Scientists identify novel gene that affects brain function

Cherenkov Effect can help make radiation therapy safer, more effective for patients with cancer

Scientists discover DNA vaccine that alleviates chronic inflammation in the body

Prexton closes €8.7 million in Series A financing to develop treatments for Parkinson’s disease

Tolero's alvocidib receives EMA orphan drug designation for treatment of AML patients

Remsima (infliximab) now available in Europe for treatment of autoimmune diseases

Sanofi announces FDA approval of Toujeo insulin to improve glycemic control in people with diabetes

New online and telephone service launched to help people take part in dementia research

Psoriasis management: an interview with Dr Sandy McBride

Monell Center to promote Anosmia Awareness Day with new educational outreach initiatives

Scientists use graphene to target, neutralise cancer stem cells

New, first-of-its-kind app helps patients with chronic pain track opioid use

Smokers who quit early does not qualify for lung cancer screening, say Mayo Clinic researchers

Sorafenib, sunitinib provide no benefit to patients with locally advanced kidney cancer

Researchers develop revolutionary approach to treat drug-resistant tumors

New TAU study may offer hope to people diagnosed with Glioblastoma multiforme

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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