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PharmaMar to begin PM1183 Phase III trial in combination with doxorubicin in SCLC

Zeltia announces today that its pharmaceutical division PharmaMar will start a Phase III trial with PM1183 in combination with doxorubicin against topotecan in SCLC, given the activity observed in an interim analysis of an ongoing Phase Ib trial. The results of this study will be presented at a prominent international cancer meeting this year, which will be soon announced.

14 Jan 2015

Individualized, patient-centered care needed to treat and monitor people with chronic pain

An independent panel convened by the National Institutes of Health concluded that individualized, patient-centered care is needed to treat and monitor the estimated 100 million Americans living with chronic pain. To achieve this aim, the panel recommends more research and development around the evidence-based, multidisciplinary approaches needed to balance patient perspectives, desired outcomes, and safety.

14 Jan 2015

Researchers identify new target that could lead to potential therapies for GBM

Researchers from Virginia Commonwealth University Massey Cancer Center and the VCU Institute for Molecular Medicine have identified a new protein-protein interaction that could serve as a target for future therapies for the most common form of brain cancer, glioblastoma multiforme (GBM).

14 Jan 2015

Ascendis Pharma initiates TransCon Treprostinil Phase 1 study in healthy volunteers

Ascendis Pharma A/S, a clinical stage biotechnology company that applies its innovative TransCon technology to address significant unmet medical needs, today announced that it has initiated a Phase 1 single ascending dose study of TransCon Treprostinil in healthy volunteers.

14 Jan 2015

High vitamin D levels boost survival for metastatic colorectal cancer patients

According to a new study led by researchers at Dana-Farber Cancer Institute, clinical trial patients with metastatic colorectal cancer who had high levels of vitamin D in their bloodstream prior to treatment with chemotherapy and targeted drugs, survived longer, on average, than patients with lower levels of the vitamin.

14 Jan 2015

Research findings may lead to new treatment for hypothyroidism

An international research team led by physician-scientists at Rush University Medical Center have gained new insights into hypothyroidism - a condition affecting about 10 million people in the U.S. - that may lead to new treatment protocols for the disease, particularly among the approximately 15 percent of patients for whom standard treatments are less effective.

14 Jan 2015

Intrexon and ZIOPHARM Oncology sign exclusive licensing agreement with MD Anderson

Intrexon Corporation, a leader in synthetic biology and its oncology partner, ZIOPHARM Oncology, today announced a broad exclusive licensing agreement with The University of Texas MD Anderson Cancer Center, including an exclusive sublicensing agreement through MD Anderson for intellectual property developed at the University of Minnesota for the development of non-viral adoptive cellular cancer immunotherapies.

14 Jan 2015

Researchers develop novel method to predict risk of liver cancer recurrence after transplantation

UCLA transplantation researchers have developed a novel method that more accurately calculates the risk of disease recurrence in liver cancer patients who have undergone a liver transplant, providing a new tool to help physicians make treatment and surveillance decisions.

14 Jan 2015

Study finds that asthma may increase obstructive sleep apnea risk

Participants in a sleep study who had asthma had an increased risk for developing obstructive sleep apnea, with this association stronger with having had asthma longer, according to a study in the January 13 issue of JAMA.

14 Jan 2015

University of Copenhagen researchers move closer to developing antidote against cocaine addiction

Researchers at the University of Copenhagen have gained new insight into the mechanism behind a protein dopamine transporter that could help in the development of future medical treatment against cocaine addiction.

14 Jan 2015

Two UTHealth professors selected as AAAS Fellows for their efforts to prevent blindness

Two professors in the School of Public Health at The University of Texas Health Science Center at Houston - Stephen Daiger, Ph.D., and Robert Hardy, Ph.D. - have been elected to the rank of Fellow in the American Association for the Advancement of Science for their efforts to prevent blindness.

14 Jan 2015

Atmospheric oxygen may play role in lung carcinogenesis, new study suggests

The ancient physician/alchemist, Paracelsus, said: "The dose makes the poison." According to a new study published in PeerJ, even oxygen may fall prey to the above adage. While essential to human life, aspects of oxygen metabolism may promote cancer. Capitalizing on the inverse relationship of oxygen concentration with elevation, researchers found lower rates of lung cancer at higher elevations, a trend that did not extend to non-respiratory cancers, suggesting that carcinogen exposure occurs via inhalation.

14 Jan 2015

$Aptose begins APTO-253 clinical study in patients with relapsed or refractory hematologic malignancies$

Aptose begins APTO-253 clinical study in patients with relapsed or refractory hematologic malignancies

Aptose Biosciences Inc., a clinical-stage company developing new therapeutics and molecular diagnostics that target the underlying mechanisms of cancer, today announced dosing of the first patient in its Phase 1b clinical study of APTO-253 in patients with relapsed or refractory hematologic malignancies.

13 Jan 2015

Study: Community-wide CVD prevention programs help reduce hospitalizations, death rates

In a rural Maine county, sustained, community-wide programs targeting cardiovascular risk factors and behavior changes were associated with reductions in hospitalization and death rates over a 40-year period (1970-2010) compared with the rest of the state. Substantial improvements were seen in control of hypertension and cholesterol, and smoking cessation, according to a study in the January 13 issue of JAMA.

13 Jan 2015

Review shows that fish compound can help combat cardiovascular disease

A major international review of a peptide originally found in fish that could be used in the battle against cardiovascular disease has been published.

13 Jan 2015

Georgia State University awarded contract to improve mental health services for Georgia's youth

Georgia State University's School of Public Health has received a five-year, $800,000 contract from the Georgia Department of Education to coordinate Youth Mental Health First Aid Training (YMHFA) and other professional development efforts designed to improve services for Georgia's youth.

13 Jan 2015

New study finds prevalence of secondhand smoke exposure among teens who have never smoked

Many teens who have never smoked are being exposed to the health dangers of tobacco. A new study by the University of Texas Medical Branch at Galveston, in collaboration with East Tennessee State University, the Indian Institute of Technology and the World Health Organization Regional Office for Africa, estimated the prevalence of secondhand smoke exposure worldwide among teens who had never smoked, and found that one third of those teens are exposed to secondhand smoke inside the home.

13 Jan 2015

U-M researchers identify how amlexanox drug improves metabolism of sugar

Researchers at the University of Michigan have identified how a promising drug in clinical trials for the treatment of obesity and related metabolic disorders improves the metabolism of sugar by generating a new signal between fat cells and the liver.

13 Jan 2015

TSRI researchers identify enzyme that produces inflammatory lipid molecules in the brain

A team led by scientists at The Scripps Research Institute has identified an enzyme that produces a class of inflammatory lipid molecules in the brain. Abnormally high levels of these molecules appear to cause a rare inherited neurodegenerative disorder, and that disorder now may be treatable if researchers can develop suitable drug candidates that inhibit this enzyme.

13 Jan 2015

New way to measure upper extremity movement in muscular dystrophy patients

Researchers at Nationwide Children's Hospital have developed a way to measure upper extremity movement in patients with muscular dystrophy using interactive video game technology. Their hope is to expand inclusion criteria for clinical trials to incorporate patients using wheelchairs.

12 Jan 2015

Medical Condition News

PharmaMar to begin PM1183 Phase III trial in combination with doxorubicin in SCLC

Individualized, patient-centered care needed to treat and monitor people with chronic pain

Researchers identify new target that could lead to potential therapies for GBM

Ascendis Pharma initiates TransCon Treprostinil Phase 1 study in healthy volunteers

High vitamin D levels boost survival for metastatic colorectal cancer patients

Research findings may lead to new treatment for hypothyroidism

Intrexon and ZIOPHARM Oncology sign exclusive licensing agreement with MD Anderson

Researchers develop novel method to predict risk of liver cancer recurrence after transplantation

Study finds that asthma may increase obstructive sleep apnea risk

University of Copenhagen researchers move closer to developing antidote against cocaine addiction

Two UTHealth professors selected as AAAS Fellows for their efforts to prevent blindness

Atmospheric oxygen may play role in lung carcinogenesis, new study suggests

Aptose begins APTO-253 clinical study in patients with relapsed or refractory hematologic malignancies

Study: Community-wide CVD prevention programs help reduce hospitalizations, death rates

Review shows that fish compound can help combat cardiovascular disease

Georgia State University awarded contract to improve mental health services for Georgia's youth

New study finds prevalence of secondhand smoke exposure among teens who have never smoked

U-M researchers identify how amlexanox drug improves metabolism of sugar

TSRI researchers identify enzyme that produces inflammatory lipid molecules in the brain

New way to measure upper extremity movement in muscular dystrophy patients

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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