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Inovio begins hTERT DNA immunotherapy trial in adults with breast, lung and pancreatic cancer

Inovio Pharmaceuticals, Inc. announced it has initiated a phase I trial of its hTERT DNA immunotherapy (INO-1400) alone or in combination with Inovio's IL-12 immune activator (INO-9012) in adults with breast, lung, or pancreatic cancer at high risk of relapse after surgery and other cancer treatments.

18 Dec 2014

Columbia University researchers analyze results of Oregon Health Experiment

Researchers at Columbia University's Mailman School of Public Health analyzed the results of the Oregon Health Experiment, where eligible uninsured individuals were randomly assigned Medicaid or to stay with their current care. Considered controversial because the experiment found no measurable gains for physical health it did reveal benefits for mental health, financial wellbeing, and preventive screening.

18 Dec 2014

Researchers examine why Mexican-Americans at increased risk for Type 2 diabetes

While people of Mexican ancestry are nearly twice as likely to develop Type 2 diabetes as people of European heritage, the majority of research in this area has focused on those of European origin.

18 Dec 2014

Two orphan receptor proteins exert fatal double whammy effect against glioblastoma cells

Two related proteins exert a lethal double whammy effect against glioblastoma cells when activated with a small molecule, say researchers at Georgetown Lombardi Comprehensive Cancer Center.

18 Dec 2014

Laparoscopic radical cystectomy can lead to reliable, long-term cancer control

Long-term survival rates following laparoscopic surgery for bladder cancer are comparable to those of open surgery, according to a study published in BJU International. The findings, which come from the largest study to date with long-term follow-up after this type of minimally invasive surgery, indicate that prospective randomized trials comparing these two bladder cancer surgeries are warranted.

18 Dec 2014

Research findings may lead to new treatment strategies for Ewing sarcoma

The genetic abnormality that drives the bone cancer Ewing sarcoma operates through two distinct processes - both activating genes that stimulate tumor growth and suppressing those that should keep cancer from developing. These findings by Massachusetts General Hospital investigators, published in the November issue of Cancer Cell, may lead to new therapies targeting these aberrant mechanisms.

18 Dec 2014

Sugar-based molecular microcapsule eliminates toxicity of anticancer agent

Johns Hopkins researchers have developed a sugar-based molecular microcapsule that eliminates the toxicity of an anticancer agent developed a decade ago at Johns Hopkins, called 3-bromopyruvate, or 3BrPA, in studies of mice with implants of human pancreatic cancer tissue. The encapsulated drug packed a potent anticancer punch, stopping the progression of tumors in the mice, but without the usual toxic effects.

18 Dec 2014

AAN urges for more research on use of medical marijuana for brain, nervous system disorders

The American Academy of Neurology is calling for more research on the use of medical marijuana for brain, spine and nervous system disorders in a new position statement released by the AAN, the world's largest association of neurologists with more than 28,000 members.

18 Dec 2014

Loyola neurologist finds little scientific evidence that brain games improve cognitive function

Computerized brain games that are advertised as a way to help boost intelligence and prevent dementia will be popular Christmas gifts this year.

18 Dec 2014

Intra-arterial stroke treatment more effective than medical management with tPA, study finds

Penumbra, Inc., the market leader in intra-arterial stroke treatment, announced that an independent study published online today in the New England Journal of Medicine found that intra-arterial stroke treatment, including the company's clot extraction technology, was shown to be significantly more effective than medical management with tissue plasminogen activator (tPA), which is the current standard of care.

18 Dec 2014

Study finds increasing shortage of stroke specialists in the U.S.

Although stroke is the No. 4 cause of death and a leading cause of disability in the United States, there's an increasing shortage of neurologists who specialize in stroke care.

18 Dec 2014

Survey highlights need for increased public education on benefits of lung cancer screening in France

A prospective nationwide survey on perceptions of lung cancer in the general population of France highlights a need for increased public education on the benefits of lung cancer screening, the good survival rates of early-stage disease and the improved outcomes with new therapeutic strategies, including targeted-therapies.

18 Dec 2014

Health promotion program reduces cardiovascular risk in obese people with serious mental illness

A health promotion program, called In SHAPE, specifically designed for people with serious mental illness, produced more fit participants and significant weight loss than a control group where participants only received a gym membership.

18 Dec 2014

University Hospital Bonn to validate accuracy of VolitionRx’s Nucleosomics technology in lung cancer

VolitionRx Limited, a life sciences company focused on developing diagnostic tests for cancer and other conditions, today announced that the University Hospital Bonn in Germany will initiate a clinical confirmatory study to assess VolitionRx’s proprietary Nucleosomics platform technology for the diagnosis of lung cancer through a blood test in individuals.

18 Dec 2014

EC grants orphan drug designation to TxCell's Col-Treg for treatment of autoimmune uveitis

TxCell SA, a biotechnology company developing innovative, cost-effective, personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that the European Commission (EC) has granted orphan drug designation to TxCell's investigational medicinal product Col-Treg, a personalized T cell immunotherapy using collagen-II specific regulatory T-cells, for the treatment of autoimmune uveitis.

18 Dec 2014

More open discussions needed when referring patients for cancer investigation, study says

GPs should consider a more overt discussion with patients when referring them for further investigation of symptoms which may indicate cancer, according to a paper published in the British Journal of General Practice.

18 Dec 2014

Researchers identify a single protein as root cause of multiple allergic reactions

Johns Hopkins and University of Alberta researchers have identified a single protein as the root of painful and dangerous allergic reactions to a range of medications and other substances. If a new drug can be found that targets the problematic protein, they say, it could help smooth treatment for patients with conditions ranging from prostate cancer to diabetes to HIV

17 Dec 2014

Insomnia is a marker for increased risk of back pain, say University of Haifa researchers

Having trouble sleeping? Then you are nearly one-and-a-half times more likely to eventually suffer from back pain, according to a new study conducted by the University of Haifa.

17 Dec 2014

Migraine headache may double risk of nervous system condition that causes Bell's palsy

Migraine headache may double the risk of a nervous system condition that causes facial paralysis, called Bell's palsy, according to a new study published in the December 17, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

17 Dec 2014

Scientists produce novel class of molecules that could help combat cancer, other diseases

Promising treatments known as biologics are on the market and under development for many serious illnesses such as cancer, but some of them come with high risks, even lethal ones. Now scientists have produced a novel class of molecules that could be as effective but without the dangerous side effects.

17 Dec 2014

Medical Condition News

Inovio begins hTERT DNA immunotherapy trial in adults with breast, lung and pancreatic cancer

Columbia University researchers analyze results of Oregon Health Experiment

Researchers examine why Mexican-Americans at increased risk for Type 2 diabetes

Two orphan receptor proteins exert fatal double whammy effect against glioblastoma cells

Laparoscopic radical cystectomy can lead to reliable, long-term cancer control

Research findings may lead to new treatment strategies for Ewing sarcoma

Sugar-based molecular microcapsule eliminates toxicity of anticancer agent

AAN urges for more research on use of medical marijuana for brain, nervous system disorders

Loyola neurologist finds little scientific evidence that brain games improve cognitive function

Intra-arterial stroke treatment more effective than medical management with tPA, study finds

Study finds increasing shortage of stroke specialists in the U.S.

Survey highlights need for increased public education on benefits of lung cancer screening in France

Health promotion program reduces cardiovascular risk in obese people with serious mental illness

University Hospital Bonn to validate accuracy of VolitionRx’s Nucleosomics technology in lung cancer

EC grants orphan drug designation to TxCell's Col-Treg for treatment of autoimmune uveitis

More open discussions needed when referring patients for cancer investigation, study says

Researchers identify a single protein as root cause of multiple allergic reactions

Insomnia is a marker for increased risk of back pain, say University of Haifa researchers

Migraine headache may double risk of nervous system condition that causes Bell's palsy

Scientists produce novel class of molecules that could help combat cancer, other diseases

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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