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Researchers use game theory to predict interactions of cancer cells

Researchers at the University of Basel and the University of East Anglia were able to predict the interactions of cancer cells using game theory. Their results have been published by the scientific journal PNAS.

28 Jan 2015

ADDF awards grant to support initiation of AGB101 Phase 3 trial for aMCI treatment

The Alzheimer's Drug Discovery Foundation announced today a $900,000 grant to AgeneBio, a pharmaceutical company developing innovative therapies for neurologic and psychiatric diseases. The grant will support the initiation of an FDA-registered Phase 3 clinical trial of AGB101, a new therapeutic treatment for amnestic mild cognitive impairment (aMCI).

28 Jan 2015

Manchester researcher discover novel way to eradicate cancer stem cells

A way to eradicate cancer stem cells, using the side-effects of commonly used antibiotics, has been discovered by a University of Manchester researcher following a conversation with his young daughter.

28 Jan 2015

Preventing obesity-related inflammation may reverse type 2 diabetes

Preventing inflammation in obese fat tissue may hold the key to preventing or even reversing type 2 diabetes, new research has found.

28 Jan 2015

HCI researchers find cell mechanism that may trigger pancreatic cancer

Researchers at Huntsman Cancer Institute at the University of Utah have found that defects in how cells are squeezed out of overcrowded tissue to die, a process called extrusion, may be a mechanism by which pancreatic cancer begins. From these findings, they may have identified an effective way to reverse the defective extrusion's effects without destroying normal tissues nearby.

28 Jan 2015

New study shows mechanism behind tubulin transport in cilia

Defective cilia can lead to a host of diseases and conditions in the human body--from rare, inherited bone malformations to blindness, male infertility, kidney disease and obesity. Scientists knew that somehow these tiny cell organelles become deformed and cause these diseases because of a problem related to their assembly, which requires the translocation of vast quantities of the vital cell protein tubulin.

28 Jan 2015

Reducing A2A adenosine receptor levels prevents memory impairments in Alzheimer's mouse model

A study by scientists from the Gladstone Institutes shows that decreasing the number of A2A adenosine receptors in a particular type of brain cells called astrocytes improved memory in healthy mice. What's more, reducing receptor levels also prevented memory impairments in a mouse model of Alzheimer's disease.

28 Jan 2015

Alzheimer's Association announces new research grants to study potential drug therapies

Many academic researchers and pharmaceutical companies have identified new Alzheimer's drug therapy candidates, but lack the funding to move them into human testing. At the same time, few funding sources support early-phase clinical drug trials. As a result, too many promising studies stall out early in the discovery process.

28 Jan 2015

Scientists identify critical molecule that helps explain why diabetics suffer from non-healing wound

One of the most troubling complications of diabetes is its effect on wound healing. Roughly 15 percent of diabetics will suffer from a non-healing wound in their lifetime. In some cases, these open ulcers on the skin lead to amputations.

28 Jan 2015

Researchers probe possibility of reversing medications' adverse cognitive effects

Whether the adverse cognitive effects of medications can be reversed is of significant importance to an aging population, their caregivers and their families, as well as to an overburdened health care system.

28 Jan 2015

Hutchinson-Gilford Progeria Syndrome can be compared to normal aging, say scientists

In a new research study, scientists from Vision Genomics, LLC, Insilico Medicine, Inc., and Howard University showed that Hutchinson-Gilford Progeria Syndrome (HGPS or Progeria) is comparable to normal aging with respect to cellular signaling pathways, and that HGPS truly recapitulates the normal aging process.

28 Jan 2015

Lund researchers find new way to identify malignant tumours in children

A research group at Lund University in Sweden has found a new way to identify the most malignant tumours in children. The method involves studying genetic 'micro-variation', rather than the presence of individual mutations.

28 Jan 2015

Improving prefrontal cortex activity could help autistic people regulate emotions

Tantrums, irritability, self-injury, depression, anxiety. These symptoms are associated with autism, but they're not considered core symptoms of the disorder. Researchers from the UNC School of Medicine are challenging this assertion. They have used functional MRI to show that - when it comes to the ability to regulate emotions - brain activity in autistic people is significantly different than brain activity in people without autism.

28 Jan 2015

Researchers explore KRAS pathway to find potential target for treating lung cancer

Despite the promise of the gene KRAS as a target for treating lung cancer, finding effective therapies has been challenging. Now researchers are traveling down the pathway to find what makes KRAS cancerous.

28 Jan 2015

Study finds that African-American people with colon cancer have lower survival rates

African-American people diagnosed with colon cancer have consistently lower survival rates compared with white patients, despite a nationwide decline in colon cancer deaths overall.

28 Jan 2015

Study provides new route for treating patients with difficult-to-treat Parkinson's symptoms

Parkinson's disease patients treated with low-frequency deep brain stimulation show significant improvements in swallowing dysfunction and freezing of gait over typical high-frequency treatment.

28 Jan 2015

Novel technique could help identify cancerous tissue during brain tumor surgery

A novel radioguided surgery technique could quickly and effectively identify residual cancer cells during brain tumor surgery, with low radiation exposure for both patients and surgeons. The study, featured in the January 2015 issue of the Journal of Nuclear Medicine, reports that Y-90 DOTATOC, a beta-minus-emitting tracer, can effectively delineate the margins of meningiomas and high-grade gliomas.

28 Jan 2015

TSRI scientists find drug candidates that can prevent degeneration of brain cells in Parkinson's

In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute have shown their drug candidates can target biological pathways involved in the destruction of brain cells in Parkinson's disease.

28 Jan 2015

Study finds no evidence that testosterone replacement therapy increases cardiovascular risk

Fears of a link between testosterone replacement therapy and cardiovascular risk are misplaced, according to a review published in this month's Mayo Clinic Proceedings. The therapy has come under widespread scrutiny in recent months, including by a federal Food and Drug Administration panel convened last fall.

28 Jan 2015

Plymouth researchers awarded grant to evaluate pulmonary rehabilitation programme in East Africa

Chronic lung disease is a growing and debilitating health issue for countries in East Africa. Resulting from respiratory infections such as TB and HIV, and lifestyle problems such as tobacco smoking and poor nutrition, chronic lung disease affects one in five adults in Africa and is a major threat to health.

28 Jan 2015

Medical Condition News

Researchers use game theory to predict interactions of cancer cells

ADDF awards grant to support initiation of AGB101 Phase 3 trial for aMCI treatment

Manchester researcher discover novel way to eradicate cancer stem cells

Preventing obesity-related inflammation may reverse type 2 diabetes

HCI researchers find cell mechanism that may trigger pancreatic cancer

New study shows mechanism behind tubulin transport in cilia

Reducing A2A adenosine receptor levels prevents memory impairments in Alzheimer's mouse model

Alzheimer's Association announces new research grants to study potential drug therapies

Scientists identify critical molecule that helps explain why diabetics suffer from non-healing wound

Researchers probe possibility of reversing medications' adverse cognitive effects

Hutchinson-Gilford Progeria Syndrome can be compared to normal aging, say scientists

Lund researchers find new way to identify malignant tumours in children

Improving prefrontal cortex activity could help autistic people regulate emotions

Researchers explore KRAS pathway to find potential target for treating lung cancer

Study finds that African-American people with colon cancer have lower survival rates

Study provides new route for treating patients with difficult-to-treat Parkinson's symptoms

Novel technique could help identify cancerous tissue during brain tumor surgery

TSRI scientists find drug candidates that can prevent degeneration of brain cells in Parkinson's

Study finds no evidence that testosterone replacement therapy increases cardiovascular risk

Plymouth researchers awarded grant to evaluate pulmonary rehabilitation programme in East Africa

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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