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Pitt researchers receive NIH grant to improve health of sedentary, overweight people

University of Pittsburgh Graduate School of Public Health researchers are flipping conventional thought on its head regarding how to improve the health of sedentary people at risk for diabetes and heart disease in a new study designed to combat a condition popularly called "sitting disease."

27 Jan 2015

Researchers decode how cancer uses cell-cell interaction mechanism to promote metastasis

Cancer uses a little-understood element of cell signaling to hijack the communication process and spread, according to Rice University researchers.

27 Jan 2015

Upregulating heme-oxygenase with hemin helps improve pericardial adipocyte morphology, function

Scientists at the University of Saskatchewan College of Medicine, Department of Physiology, Saskatoon, Canada, led by Dr. Joseph Fomusi Ndisang have determined that upregulating heme-oxygenase with hemin improves pericardial adipocyte morphology and function.

27 Jan 2015

Progenitor cells responsible for generation and maintenance of Merkel cells

Researchers have identified a population of "progenitor" cells in the skin that are solely responsible for the generation and maintenance of touch-sensing Merkel cells. The study appears in The Journal of Cell Biology.

27 Jan 2015

Alcohol drinking pattern influences risk of cirrhosis

Approximately 170,000 people die from alcoholic cirrhosis of the liver in Europe every year. Although alcohol is the most important risk factor, less is known about the significance of different patterns of drinking. Currently scientists believe that cirrhosis is a function of the volume of alcohol consumed irrespective of patterns of drinking. Investigators have now established that alcohol drinking pattern has a significant influence on the risk of cirrhosis and that daily drinking increases that risk compared with drinking less frequently.

27 Jan 2015

Flexible work hours may help curb sleep deficiency

Giving employees more control over their work schedules may help curb sleep deficiency, according to health researchers.

27 Jan 2015

Attaching Epirubicin drug to nanodiamonds eliminates chemoresistant cancer stem cells

A study led by the National University of Singapore found that attaching chemotherapy drug Epirubicin to nanodiamonds effectively eliminates chemoresistant cancer stem cells. The findings were first published online in ACS Nano, the official journal of the American Chemical Society, in December 2014.

26 Jan 2015

Research findings may accelerate work to safely control diabetes

For those with diabetes, managing blood sugar is a balancing act -- if blood sugar is too high it raises the risk for nerve damage, blindness, kidney failure, and heart trouble, and if too low it can lead to a seizure or unconsciousness.

24 Jan 2015

International scientists take new path in epilepsy research

An international team of scientists together with the University of Bonn Hospital have taken a new path in the research into causes of epilepsy: The researchers determined the networks of the active genes and, like a dragnet, looked for the "main perpetrators" using a computer model.

24 Jan 2015

Bayer, MD Anderson partner to evaluate how a drug may affect patient's disease-related symptoms

When cancer patients take part in a clinical trial to develop new therapies, they and their physicians want to know how they will feel and function during treatment. A new collaboration between Bayer and The University of Texas MD Anderson Cancer Center will go straight to the patients to learn how certain investigational new drugs affect them.

24 Jan 2015

Survey sheds light on issues that limit acute heart failure patients' ability to care for themselves

A tool designed to assess what interferes with acute heart failure patients' ability to care for themselves after hospital discharge holds promise for improving patient outcomes and reducing readmissions to the hospital.

24 Jan 2015

Study examines effects of beetroot juice on physical function of COPD patients

A Wake Forest University study to investigate the effects of acute beetroot juice ingestion on the exercise capacity of COPD patients shows some promise, but a larger clinical trial is needed to verify results.

23 Jan 2015

Gem Pharmaceuticals enrolls initial soft tissue sarcoma patients in GPX-150 Phase 2 clinical trial

Gem Pharmaceuticals announced today that the initial soft tissue sarcoma (STS) patients have been enrolled into the Company's Phase 2 clinical trial. This open-label study will assess the efficacy and safety of Gem's lead compound, GPX-150 (an investigational medication), in approximately 30 adults as first-line therapy for advanced or metastatic disease.

23 Jan 2015

New research could help pave way to new cancer therapies

New research from the Hebrew University of Jerusalem shows that the most common form of white blood cells, called neutrophils, contain many different subtypes, of which some fight the development of cancer and others promote its progression. The research could help pave the way to new therapies that fight cancer by increasing anti-tumor neutrophils while limiting pro-tumor neutrophils.

23 Jan 2015

Altered AHNAK gene may open door to improved treatment for keloid scars

Researchers at Henry Ford Hospital in Detroit have identified a gene that may offer a better understanding of how keloid scars develop and potentially open the door to improved treatment for the often painful, itchy and tender scars.

23 Jan 2015

Study uses 'systems genetics' approach to identify potential target for epilepsy

A single gene that coordinates a network of about 400 genes involved in epilepsy could be a target for new treatments, according to research.

23 Jan 2015

International study identifies genetic factors that influence the size of brain structures

An international study, which included researchers from NUI Galway, has identified significant genetic factors that influence the size of structures within the brain. It is hoped these new insights may help scientists better understand disorders such as schizophrenia, Alzheimer's disease and epilepsy.

23 Jan 2015

PKC enzymes categorized as cancer promoters are actually tumor suppressors

Upending decades-old dogma, a team of scientists at the University of California, San Diego School of Medicine say enzymes long categorized as promoting cancer are, in fact, tumor suppressors and that current clinical efforts to develop inhibitor-based drugs should instead focus on restoring the enzymes' activities.

23 Jan 2015

Scientists identify new molecular pathway that controls axonal degeneration following injury

Axons connect neurons with each other to form the neural networks that underpin the vital functions of perception, motility, cognition, and memory. In many neurodegenerative disorders, from traumatic injury or toxic damage to diseases such as Alzheimer's or Parkinson's disease, axonal degeneration represents an essential pathological feature.

23 Jan 2015

New discovery may help doctors develop better treatments for brain, spinal cord injuries

In a discovery that could dramatically affect the treatment of brain and spinal cord injuries, researchers have identified a previously unknown, beneficial immune response that occurs after injury to the central nervous system.

23 Jan 2015

Medical Condition News

Pitt researchers receive NIH grant to improve health of sedentary, overweight people

Researchers decode how cancer uses cell-cell interaction mechanism to promote metastasis

Upregulating heme-oxygenase with hemin helps improve pericardial adipocyte morphology, function

Progenitor cells responsible for generation and maintenance of Merkel cells

Alcohol drinking pattern influences risk of cirrhosis

Flexible work hours may help curb sleep deficiency

Attaching Epirubicin drug to nanodiamonds eliminates chemoresistant cancer stem cells

Research findings may accelerate work to safely control diabetes

International scientists take new path in epilepsy research

Bayer, MD Anderson partner to evaluate how a drug may affect patient's disease-related symptoms

Survey sheds light on issues that limit acute heart failure patients' ability to care for themselves

Study examines effects of beetroot juice on physical function of COPD patients

Gem Pharmaceuticals enrolls initial soft tissue sarcoma patients in GPX-150 Phase 2 clinical trial

New research could help pave way to new cancer therapies

Altered AHNAK gene may open door to improved treatment for keloid scars

Study uses 'systems genetics' approach to identify potential target for epilepsy

International study identifies genetic factors that influence the size of brain structures

PKC enzymes categorized as cancer promoters are actually tumor suppressors

Scientists identify new molecular pathway that controls axonal degeneration following injury

New discovery may help doctors develop better treatments for brain, spinal cord injuries

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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