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Survey: Physicians, patients overestimate risk of heart attack or death for possible ACS

Both physicians and patients overestimate the risk of heart attack or death for possible acute coronary syndrome (ACS) as well as the potential benefit of hospital admission for possible ACS.

12 Mar 2015

Patients who receive definitive CCRT treatment for stage III NSCLC have longer overall survival

Patients treated with definitive concurrent chemotherapy and radiation therapy (CCRT) for stage III non-small cell lung cancer (NSCLC) have longer overall survival when treated by highly experienced facilities, whether or not they are academic or community cancer centers.

12 Mar 2015

Simple blood test could be developed to diagnose Alzheimer's disease, say UCLA researchers

UCLA researchers have provided the first evidence that a simple blood test could be developed to confirm the presence of beta amyloid proteins in the brain, which is a hallmark of Alzheimer's disease.

12 Mar 2015

New study shows how presenilin gene mutations may lead to familial Alzheimer's disease

Mutations in the presenilin-1 gene are the most common cause of inherited, early-onset forms of Alzheimer's disease. In a new study, published in Neuron, scientists replaced the normal mouse presenilin-1 gene with Alzheimer's-causing forms of the human gene to discover how these genetic changes may lead to the disorder.

12 Mar 2015

Rat study reveals role of lead in schizophrenia

A study of the brains of rats exposed to lead has uncovered striking similarities with what is known about the brains of human schizophrenia patients, adding compelling evidence that lead is a factor in the onset of schizophrenia.

12 Mar 2015

Glucocorticoid therapies promote functional recovery of blood-brain barrier after blast injury

Barclay Morrison III, associate professor of biomedical engineering at Columbia Engineering, has led the first study to determine underlying biological mechanisms that promote functional recovery of the blood-brain barrier (BBB) after blast injury. The research demonstrates that treatment with the glucocorticoid, dexamethasone, after primary blast injury promotes rapid recovery of an in vitro model of the BBB, a highly restrictive semi-permeable barrier whose primary function is to maintain the brain's microenvironment and protect it from potentially toxic substances.

12 Mar 2015

Implantable defibrillators help patients with hypertrophic cardiomyopathy live longer

Newly published research led by the Minneapolis Heart Institute Foundation and Tufts Medical Center in Boston shows that implantable defibrillators (ICDs), along with other modern treatments, have reduced mortality rates and are helping patients with hypertrophic cardiomyopathy (HCM) live longer, including normal life expectancy.

12 Mar 2015

Two researchers to receive Potamkin Prize for research on Alzheimer's disease

The American Academy of Neurology and the American Brain Foundation are awarding the 2015 Potamkin Prize for Research in Pick's, Alzheimer's and Related Diseases to Peter Davies, PhD, of the Feinstein Institute for Medical Research in Manhasset, NY, and Reisa A. Sperling, MD, of the Brigham and Women's Hospital and Massachusetts General Hospital in Boston.

11 Mar 2015

Recruitment completed for Phase III PROUD-PV trial of P1101 for treatment of polycythemia vera

PharmaEssentia (Taipei, Taiwan) and AOP Orphan (Vienna, Austria) announce the completion of recruitment for the Phase III trial PROUD-PV to support global marketing of P1101 (Ropeginterferon alfa-2b), a novel, long-acting, mono-pegylated interferon for the first line treatment of polycythemia vera.

11 Mar 2015

University of Cambridge's Alastair Compston wins 2015 John Dystel Prize for MS Research

The American Academy of Neurology and the National Multiple Sclerosis Society are awarding the 2015 John Dystel Prize for MS Research to Alastair Compston, MBBS, PhD, Professor of Neurology at the University of Cambridge.

11 Mar 2015

New stem cell treatment reverses disability in certain MS patients

A PIONEERING new stem cell treatment ‘rebooting’ the immune system in some multiple sclerosis sufferers is being hailed as an encouraging step forward in the treatment of the disease in sufferers who fail to respond to standard therapies.

11 Mar 2015

Understanding the role of next generation sequencing in stratified cancer medicine

Oxford Gene Technology, The Molecular Genetics Company, has teamed up with clinical research experts in a new article available online, discussing the role of next generation sequencing (NGS) in cancer medicine.

From Oxford Gene Technology 11 Mar 2015

New injectable polymer could strengthen blood clots

Most military battlefield casualties die before ever reaching a surgical hospital. Of those soldiers who might potentially survive, most die from uncontrolled bleeding.

11 Mar 2015

Research findings offer new insights into pathophysiology of PTSD

Researchers at the Veterans Affairs San Diego Healthcare System and University of California, San Diego School of Medicine, with colleagues in New York and the United Kingdom, have identified genetic markers, derived from blood samples that are linked to post-traumatic stress disorder (PTSD). The markers are associated with gene networks that regulate innate immune function and interferon signaling.

11 Mar 2015

Type 2 diabetes less common in patients with familial hypercholesterolemia

The prevalence of type 2 diabetes among 25,000 patients with familial hypercholesterolemia (a genetic disorder characterized by high low-density lipoprotein [LDL] cholesterol levels) was significantly lower than among unaffected relatives, with the prevalence varying by the type of gene mutation, according to a study in the March 10 issue of JAMA.

11 Mar 2015

Excess dietary sodium can adversely affect organs

You may think you're one of the lucky ones who can eat all the salty snacks and convenience foods you want and still register low numbers on the blood pressure cuff. But, new research suggests you may not be so lucky after all.

11 Mar 2015

Insomnia symptoms affect suicide risk among people who drink alcohol

Insomnia symptoms affect the risk of suicide among people who drink alcohol, according to a groundbreaking study led by the director of Mississippi State University's Sleep, Suicide and Aging Laboratory.

11 Mar 2015

Naproxen and omeprazole combination effective in preventing bladder cancer

The anti-inflammatory class of drugs NSAIDs have shown great promise in preventing cancers including colon, esophagus and skin. However, they can increase the risks of heart attacks, ulcers and rare but potentially life-threatening bleeds.

11 Mar 2015

LSDF announces new Matching grants to promote treatments for devastating medical conditions

The Life Sciences Discovery Fund today announced nearly $1 million in Matching grants to two Washington-based companies to promote translation of promising treatments for devastating medical conditions from the laboratory to the commercial marketplace.

11 Mar 2015

Scientists develop mathematical model to digitally map communication between heart cells

A team of scientists led by Johns Hopkins cardiologist and biomedical engineer Hiroshi Ashikaga, M.D., Ph.D., has developed a mathematical model to measure and digitally map the beat-sustaining electrical flow between heart cells.

11 Mar 2015

Medical Condition News

Survey: Physicians, patients overestimate risk of heart attack or death for possible ACS

Patients who receive definitive CCRT treatment for stage III NSCLC have longer overall survival

Simple blood test could be developed to diagnose Alzheimer's disease, say UCLA researchers

New study shows how presenilin gene mutations may lead to familial Alzheimer's disease

Rat study reveals role of lead in schizophrenia

Glucocorticoid therapies promote functional recovery of blood-brain barrier after blast injury

Implantable defibrillators help patients with hypertrophic cardiomyopathy live longer

Two researchers to receive Potamkin Prize for research on Alzheimer's disease

Recruitment completed for Phase III PROUD-PV trial of P1101 for treatment of polycythemia vera

University of Cambridge's Alastair Compston wins 2015 John Dystel Prize for MS Research

New stem cell treatment reverses disability in certain MS patients

Understanding the role of next generation sequencing in stratified cancer medicine

New injectable polymer could strengthen blood clots

Research findings offer new insights into pathophysiology of PTSD

Type 2 diabetes less common in patients with familial hypercholesterolemia

Excess dietary sodium can adversely affect organs

Insomnia symptoms affect suicide risk among people who drink alcohol

Naproxen and omeprazole combination effective in preventing bladder cancer

LSDF announces new Matching grants to promote treatments for devastating medical conditions

Scientists develop mathematical model to digitally map communication between heart cells

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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