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Pharmacyclics launches informCLL registry to explore natural history of CLL patients

Pharmacyclics, Inc. today announced the launch of informCLL, a large, observational, prospective registry that will explore the natural history of chronic lymphocytic leukemia (CLL), examine how IMBRUVICA (ibrutinib) and other approved targeted therapies are being used to treat patients with CLL, and provide a comparison to treatments using conventional chemoimmunotherapy (CIT).

5 Dec 2014

Computer games benefit stroke survivors, improve arm movements

Stroke survivors can have "significant" improvement in arm movements after using the Nintendo Wii as physiotherapy according to researchers.

5 Dec 2014

Risk of developing obesity, type 2 diabetes and cardiovascular disease starts in pregnancy

The risk of developing type 2 diabetes, obesity, and cardiovascular disease is affected by exposures in the uterus. Researchers at Lund University in Sweden are now calling for updated guidelines in light of research evidence from the past decades.

5 Dec 2014

$New study examines efficacy of brace application for treatment of spinal compression fractures$

New study examines efficacy of brace application for treatment of spinal compression fractures

Compression fractures in the spine due to osteoporosis, a common condition causing progressive bone loss and increased fracture risk, are especially common in older women. A new study appearing in the December 3rd issue of the Journal of Bone & Joint Surgery found that patients who wore a brace as treatment for a spinal compression fracture had comparable outcomes in terms of pain, function and healing when compared to patients who did not wear a brace.

5 Dec 2014

Researchers discover essential role of intestinal immune system in controlling energy metabolism

A group of UCL researchers (Louvain Drug Research Institute) identified an unsuspected mechanism impacting the development of obesity and diabetes type 2 after following a diet with a high dose of fat nutrition.

5 Dec 2014

Researchers develop new tool for global leaders to better control cancer

With the number of global cancer cases expected to increase by more than 50 percent by 2030, researchers around the globe have collaborated to create a new tool for global leaders to determine what actions they must take to better control cancer.

5 Dec 2014

Breakthrough research could lead to prosthetic retinas for people suffering from retinal damage

Scientists have developed a new light-sensitive film that could one day form the basis of a prosthetic retina to help people suffering from retinal damage or degeneration. Hebrew University of Jerusalem researchers collaborated with colleagues from Tel Aviv University and Newcastle University in the research, which was published in the journal Nano Letters.

5 Dec 2014

Two medical imaging techniques could predict effectiveness of TB drugs

Two medical imaging techniques, called positron emission tomography (PET) and computed tomography (CT), could be used in combination as a biomarker to predict the effectiveness of antibiotic drug regimens being tested to treat tuberculosis (TB) patients, according to researchers at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

5 Dec 2014

Primary care can help tackle mental health care disparities among ethnic minorities

Primary care that includes mental health screenings and treatments that take into account a patient's language and cultural background can help address mental health care disparities among ethnic minorities, according to psychologists, physicians and other health care experts writing in a special issue of Psychological Services, published by the American Psychological Association.

5 Dec 2014

Landmark CoMMpass Study data now available through MMRF Researcher Gateway

The Multiple Myeloma Research Foundation announced today that new data from the landmark CoMMpass Study is now available to researchers via the MMRF's Researcher Gateway, an online, open-access portal designed to make key genomic and clinical data publically available for additional study.

5 Dec 2014

Added benefit of nalmefene not proven for alcohol dependence

Nalmefene (trade name Selincro) has been approved since February 2013 for people with alcohol dependence who currently drink a lot of alcohol, but who do not have physical withdrawal symptoms and who do not require immediate detoxification. The German Institute for Quality and Efficiency in Health Care examined in a dossier assessment whether the drug offers an added benefit over the appropriate comparator therapy in this patient group.

5 Dec 2014

Hormone leptin increases blood pressure that occurs with weight gain

Leptin, a hormone that regulates the amount of fat stored in the body, also drives the increase in blood pressure that occurs with weight gain, according to researchers from Monash University and the University of Cambridge.

5 Dec 2014

Researchers discover link between obesity and hypertension

The link between obesity and cardiovascular diseases is well acknowledged. Being obese or overweight is a major risk factor for the development of elevated blood pressure, and cardiovascular diseases. But it has net been known how obesity increases the risk of high blood pressure, making it difficult to develop evidence based therapies for obesity, hypertension and heart disease.

5 Dec 2014

Scientists seek to improve stem cell transplant outcomes using DNA sequencing, mathematical modeling

Is the human immune system similar to the weather, a seemingly random yet dynamical system that can be modeled based on past conditions to predict future states? Scientists at VCU Massey Cancer Center's award-winning Bone Marrow Transplant (BMT) Program believe it is, and they recently published several studies that support the possibility of using next-generation DNA sequencing and mathematical modeling to not only understand the variability observed in clinical outcomes of stem cell transplantation, but also to provide a theoretical framework to make transplantation a possibility for more patients who do not have a related donor.

5 Dec 2014

UB researchers explore link between behavioral symptoms and chronic traumatic encephalopathy

Aggression, violence, depression, suicide. Media reports routinely link these behavioral symptoms with chronic traumatic encephalopathy (CTE), the neurodegenerative brain disease, in former football players.

5 Dec 2014

New study investigates rate of HIV testing in patients with mental illnesses

People with mental illness are more likely to have been tested for HIV than those without mental illness, according to a new study from a team of researchers at Penn Medicine and the U.S. Centers for Disease Control and Prevention published online this week in AIDS Patient Care and STDs.

5 Dec 2014

Research to Prevent Blindness, IRRF partner to advance knowledge about AMD

Research to Prevent Blindness, the leading eye research foundation, is partnering with the International Retinal Research Foundation to advance knowledge about age-related macular degeneration (AMD) through novel stem cell research.

5 Dec 2014

Researchers developing eye tests to evaluate diabetic neuropathy receive global recognition

Researchers from QUT's Institute of Health and Biomedical Innovation developing eye tests to assess diabetic neuropathy and pave the way for earlier treatment are key partners in a consortium awarded $US1.1 million from the leading American medical research agency.

5 Dec 2014

Going to bed late evenings linked to repetitive negative thoughts

When you go to bed, and how long you sleep at a time, might actually make it difficult for you to stop worrying. So say Jacob Nota and Meredith Coles of Binghamton University in the US, who found that people who sleep for shorter periods of time and go to bed very late at night are often overwhelmed with more negative thoughts than those who keep more regular sleeping hours.

5 Dec 2014

People with first-episode psychosis may benefit from medication treatment changes, study finds

Many patients with first-episode psychosis receive medications that do not comply with recommended guidelines for first-episode treatment, researchers have found. Current guidelines emphasize low doses of antipsychotic drugs and strategies for minimizing the side effects that might contribute to patients stopping their medication.

5 Dec 2014

Medical Condition News

Pharmacyclics launches informCLL registry to explore natural history of CLL patients

Computer games benefit stroke survivors, improve arm movements

Risk of developing obesity, type 2 diabetes and cardiovascular disease starts in pregnancy

New study examines efficacy of brace application for treatment of spinal compression fractures

Researchers discover essential role of intestinal immune system in controlling energy metabolism

Researchers develop new tool for global leaders to better control cancer

Breakthrough research could lead to prosthetic retinas for people suffering from retinal damage

Two medical imaging techniques could predict effectiveness of TB drugs

Primary care can help tackle mental health care disparities among ethnic minorities

Landmark CoMMpass Study data now available through MMRF Researcher Gateway

Added benefit of nalmefene not proven for alcohol dependence

Hormone leptin increases blood pressure that occurs with weight gain

Researchers discover link between obesity and hypertension

Scientists seek to improve stem cell transplant outcomes using DNA sequencing, mathematical modeling

UB researchers explore link between behavioral symptoms and chronic traumatic encephalopathy

New study investigates rate of HIV testing in patients with mental illnesses

Research to Prevent Blindness, IRRF partner to advance knowledge about AMD

Researchers developing eye tests to evaluate diabetic neuropathy receive global recognition

Going to bed late evenings linked to repetitive negative thoughts

People with first-episode psychosis may benefit from medication treatment changes, study finds

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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