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Cholesterol efflux appears to be superior indicator of cardiovascular risk

Groundbreaking research from UT Southwestern Medical Center shows that cholesterol efflux capacity (cholesterol efflux), which measures HDL cholesterol function, appears to be a superior indicator of cardiovascular risk and a better target for therapeutic treatments than standard measurements of HDL. Current measurement methods reflect only the circulating levels of HDL and not the functional properties of this lipoprotein.

19 Nov 2014

Research breakthrough offers hope for patients with severe spinal cord injuries

Case Western Reserve researchers have developed a procedure that restores function to muscles involved in the control of breathing - even when they have been paralyzed for more than a year. The breakthrough offers hope that one day patients with severe spinal cord injuries will be able to breathe again without the assistance of a ventilator.

19 Nov 2014

New study identifies crizotinib drug as possible new coating for drug-eluting stents

A new study has identified an FDA approved cancer drug, crizotinib, as a possible new coating for drug-eluting stents. Researchers found that crizotinib in mice helped prevent the narrowing of blood vessels after stenting without affecting the blood vessel lining.

19 Nov 2014

UEA researcher awarded NIHR grant to reduce avoidable asthma deaths in the UK

Leading researcher Dr. Andrew Wilson from the University of East Anglia has been awarded £1.7million in funding from the National Institute for Health Research, enabling the Asthma UK Centre for Applied Research to identify people most at risk of an asthma attack in order to reduce the high number of avoidable asthma deaths.

19 Nov 2014

Scientists reveal mechanisms that create 'Mexican waves' in brain

Scientists have revealed the mechanisms that enable certain brain cells to persuade others to create 'Mexican waves' linked with cognitive function.

19 Nov 2014

Cardiac stem cell treatment restores heart function damaged by Duchenne muscular dystrophy

Researchers at the Cedars-Sinai Heart Institute have found that injections of cardiac stem cells might help reverse heart damage caused by Duchenne muscular dystrophy, potentially resulting in a longer life expectancy for patients with the chronic muscle-wasting disease.

18 Nov 2014

Lifestyle of young people could pose risk for developing diabetes mellitus

Research performed by the University of Veracruz, in the east coast of Mexico, called Lifestyles Nutrition Students and Risk of Type II Diabetes, showed that the lifestyle of young people between 17 and 24 years of age, like lack of physical activity, mild psychological stress, and the omission of breakfast could pose a risk for developing diseases such as diabetes mellitus.

18 Nov 2014

Moffitt announces development of innovative investigational biologic agent for MDS

In a major step to treat patients living with Myelodysplastic Syndromes (MDS), a group of diseases that affect the bone marrow and blood, Moffitt Cancer Center today announced the development of an innovative investigational biologic agent that could improve patient response and outcomes for MDS and other diseases.

18 Nov 2014

Nationwide STEMI rates drop, reveals Vanderbilt study

The most emergent form of heart attacks is decreasing nationwide, but this declining incidence could affect emergency departments' quality and timeliness of care.

18 Nov 2014

Scientists find cells responsible for memory problems after sleep loss

Sleep is a critical period for memory consolidation, and most people don't get enough. Research has shown that even brief periods of sleep deprivation can lead to deficits in memory formation.

18 Nov 2014

Common anti-malaria medicine could have significant impact on colorectal cancer

Medical experts say a common malaria drug could have a significant impact on colorectal cancer providing a cheap adjunct to current expensive chemotherapy.

18 Nov 2014

3SBio enters into exclusive license agreement with PharmAbcine for Tanibirumab

3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, today announced it has entered into an exclusive license with PharmAbcine, Inc. for the development, manufacturing and marketing of Tanibirumab, an anti-VEGFR2/KDR antibody for cancer in the territory of Greater China (including Mainland China, Taiwan, Hong Kong and Macau) and several emerging countries, including Thailand, Brazil and Russia.

18 Nov 2014

Scientists identify how ADAR1 gene mutation can lead to diseases

Scientists have discovered how a gene mutation can lead to diseases that occur when the immune system attacks the body by mistake.

18 Nov 2014

Investigational treatment shows promise against Marfan syndrome

An investigational treatment for Marfan syndrome is as effective as the standard therapy at slowing enlargement of the aorta, the large artery of the heart that delivers blood to the body, new research shows. The findings indicate a second treatment option for Marfan patients, who are at high risk of sudden death from tears in the aorta.

18 Nov 2014

Health Canada to review evidence on the safety of long-term use of prescription blood-thinners

Health Canada is aware of and will be reviewing new evidence on the safety of long-term use of the prescription blood-thinners clopidogrel (Plavix) and prasugrel (Effient).

18 Nov 2014

Study identifies new gene for progressive form of epilepsy

A study led by researchers at University of Helsinki, Finland and Universities of Melbourne and South Australia has identified a new gene for a progressive form of epilepsy. The findings of this international collaborative effort have been published today, 17 November 2014, in Nature Genetics.

18 Nov 2014

University of Sheffield scientists find significant rise in serious heart infection

Scientists at the University of Sheffield have identified a significant rise in the number of people diagnosed with a serious heart infection alongside a large fall in the prescribing of antibiotic prophylaxis to dental patients.

18 Nov 2014

New research suggests potential role for MEK inhibitors in type 2 diabetes

A research team led by Brigham and Women's Hospital and Dana-Farber Cancer Institute has uncovered surprising new findings that underscore the role of an important signaling pathway, already known to be critical in cancer, in the development of type 2 diabetes.

18 Nov 2014

Cigna Foundation awards World of Difference grant to improve heart healthy behaviors in women

When it comes to hearts, men and women are not created equally. Women who have experienced a heart attack have a higher risk of a subsequent heart attack, or death, compared to men, according to the American Heart Association.

18 Nov 2014

Research finding could have major implications for diabetes treatment

Harvard Stem Cell Institute researchers, representing five Harvard departments and affiliated institutions as well as the Massachusetts Institute of Technology, have demonstrated that adult cells, reprogrammed into another cell type in a living animal, can remain functional over a long period.

18 Nov 2014