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UMMS scientists awarded $9.5 million grant to study Fragile X syndrome

The National Institutes of Health has awarded a $9.5 million grant to investigators at the University of Massachusetts Medical School to establish a Center for Collaborative Research in Fragile X, one of three centers designated by the NIH.

18 Nov 2014

Study reveals association between high burden of AFib and lower cognitive function

iRhythm Technologies, Inc. announced today that study results presented during the American Heart Association Scientific Sessions showed an association between a high burden of atrial fibrillation (AFib) and lower cognitive function, specifically executive and verbal function.

18 Nov 2014

Simple tests can help differentiate between early-stage PD and atypical parkinsonism

Two simple tests conducted during the neurological exam can help clinicians differentiate between early-stage Parkinson's disease (PD) and atypical parkinsonism. By asking patients to perform a tandem gait test and inquiring whether they are still able to ride a bicycle, clinicians can ascertain whether medio-lateral balance is impaired, a defining characteristic of atypical parkinsonism.

18 Nov 2014

ZS Pharma reports positive ZS-9 Phase 3 clinical trial for treatment of hyperkalemia

ZS Pharma, a biopharmaceutical company developing novel treatments for kidney, cardiovascular, liver and metabolic disorders, today presented detailed results from HARMONIZE (ZS004) at the late-breaking Clinical Science Special Reports Session of the American Heart Association Scientific Sessions.

18 Nov 2014

New preclinical study shows RG-012 may provide therapeutic benefit for Alport syndrome patients

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today announced that positive new preclinical data was presented on RG-012 for the treatment of renal dysfunction in Alport syndrome patients at the American Society of Nephrology's Kidney Week 2014 meeting being held November 11-16, 2014 in Philadelphia, PA.

18 Nov 2014

Curcumin and tackling mesothelioma: an interview with Dr. Afshin Dowlati

An important point about this work is that the research into curcumin was conducted following a discovery about mesothelioma, rather than being the primary endpoint of the study.

17 Nov 2014

Study: Chemotherapy following radiation therapy improves survival in adults with low-grade gliomas

A chemotherapy regimen consisting of procarbazine, CCNU, and vincristine (PCV) administered following radiation therapy improved progression-free survival and overall survival in adults with low-grade gliomas, a form of brain cancer, when compared to radiation therapy alone.

17 Nov 2014

Study suggests that beta blockers may benefit patients suffering from HFPEF

A novel registry study from Karolinska Institutet in Sweden suggests that beta blockers may benefit also patients suffering from a relatively unknown form of heart failure called HFPEF, which today lacks well-established treatment.

17 Nov 2014

UT Southwestern researchers identify new gene mutations involved in certain kidney cancers

Using next generation gene sequencing techniques, cancer researchers at UT Southwestern Medical Center have identified more than 3,000 new mutations involved in certain kidney cancers, findings that help explain the diversity of cancer behaviors.

17 Nov 2014

Study underlines critical role of Fragile X mental retardation protein in brain development

Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability (ID), as well as the most frequent monogenic cause of autism spectrum disorders (ASD). FXS is caused by the absence or incorrect production of the protein FMRP (Fragile X Mental Retardation Protein).

17 Nov 2014

Vital exhaustion may increase risk of first-time cardiovascular disease by 36%

Fatigue, increased irritability, and feeling demoralized, may raise a healthy man or woman's risk of first-time cardiovascular disease by 36 percent, according to a study led by researchers at Mount Sinai St. Luke's and Mount Sinai Roosevelt hospitals presented on Nov. 17 at the American Heart Association's Scientific Sessions 2014 in Chicago, IL.

17 Nov 2014

Research finding points to potential new treatment for metabolic disorders

Researchers at the University of Michigan have discovered how a previously unknown hormone serves as a messenger from fat cells to the liver and are investigating the potential of developing a new treatment for metabolic disorders.

17 Nov 2014

NIH study finds limited kidney benefit from more rigorous blood pressure treatment

Using two drugs was no more effective than a single drug in slowing disease progression in people with autosomal dominant polycystic kidney disease (ADPKD), according to two studies funded by the National Institutes of Health. One of the studies also showed that rigorous blood pressure treatment slowed growth of kidney cysts, a marker of ADPKD, but had little effect on kidney function compared to standard blood pressure treatment.

17 Nov 2014

$Study finds link between body weight change and hip fracture risk among Singapore Chinese$

Study finds link between body weight change and hip fracture risk among Singapore Chinese

While a low body mass index (BMI) of less than 20 kg/m2 has been shown to be an independent risk factor for hip fractures, far less is known about the relationship of body weight changes on hip fracture risk.

17 Nov 2014

Two hospital staff shortlisted as finalists in NHS Leadership Recognition Awards

A CONSULTANT nurse leading the way in cancer care and a manager inspiring a generation of NHS professionals to improve the quality, safety and value of care they provide are to be recognised at a regional award scheme celebrating great leaders in the NHS.

17 Nov 2014

Sanofi, Genzyme announce FDA approval of Lemtrada for treatment of relapsing forms of MS

Sanofi and its subsidiary Genzyme announced today that the U.S. Food and Drug Administration has approved Lemtrada (alemtuzumab) for the treatment of patients with relapsing forms of multiple sclerosis (MS). Because of its safety profile, the use of Lemtrada should generally be reserved for patients who have had an inadequate response to two or more drugs indicated for the treatment of MS.

17 Nov 2014

New research finds prevalence of obesity among teens with disabilities

Teens with physical or mental disabilities are more likely to be obese compared to adolescents without disabilities, according to new research presented today at the American Public Health Association's 142nd Annual Meeting in New Orleans.

17 Nov 2014

Chemical compound in coffee may help prevent damaging effects of obesity

Researchers at the University of Georgia have discovered that a chemical compound commonly found in coffee may help prevent some of the damaging effects of obesity.

17 Nov 2014

Spinal cord injuries can cause brain degeneration, find UM SOM researchers

Most research on spinal cord injuries has focused on effects due to spinal cord damage and scientists have neglected the effects on brain function. University of Maryland School of Medicine researchers have found for the first time that spinal cord injuries (SCI) can cause widespread and sustained brain inflammation that leads to progressive loss of nerve cells, with associated cognitive problems and depression.

17 Nov 2014

Using cardiac biomarkers to identify NSTEMI and ACS patients: an interview with Peter Mason

ACS is currently identified through the use of ECGs pre-hospital and the confirmed via a Troponin biomarker test once in the acute setting.

16 Nov 2014

Medical Condition News

UMMS scientists awarded $9.5 million grant to study Fragile X syndrome

Study reveals association between high burden of AFib and lower cognitive function

Simple tests can help differentiate between early-stage PD and atypical parkinsonism

ZS Pharma reports positive ZS-9 Phase 3 clinical trial for treatment of hyperkalemia

New preclinical study shows RG-012 may provide therapeutic benefit for Alport syndrome patients

Curcumin and tackling mesothelioma: an interview with Dr. Afshin Dowlati

Study: Chemotherapy following radiation therapy improves survival in adults with low-grade gliomas

Study suggests that beta blockers may benefit patients suffering from HFPEF

UT Southwestern researchers identify new gene mutations involved in certain kidney cancers

Study underlines critical role of Fragile X mental retardation protein in brain development

Vital exhaustion may increase risk of first-time cardiovascular disease by 36%

Research finding points to potential new treatment for metabolic disorders

NIH study finds limited kidney benefit from more rigorous blood pressure treatment

Study finds link between body weight change and hip fracture risk among Singapore Chinese

Two hospital staff shortlisted as finalists in NHS Leadership Recognition Awards

Sanofi, Genzyme announce FDA approval of Lemtrada for treatment of relapsing forms of MS

New research finds prevalence of obesity among teens with disabilities

Chemical compound in coffee may help prevent damaging effects of obesity

Spinal cord injuries can cause brain degeneration, find UM SOM researchers

Using cardiac biomarkers to identify NSTEMI and ACS patients: an interview with Peter Mason

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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