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Scientists uncover mechanism and possible treatment to reverse immune suppression in liver disease patients

The mechanism which underlies the susceptibility of liver disease patients to life-threatening infection has been uncovered by Wellcome Trust-funded medical scientists, who have also suggested a possible treatment to reverse immune suppression in these patients.

15 Apr 2014

UK study finds link between low vitamin D status and non-alcoholic fatty liver disease in British children

A UK study investigating the link between low vitamin D status and non-alcoholic fatty liver disease (NAFLD) in British children has identified a genetic variant associated with the disease's severity.

15 Apr 2014

European scientists set up new therapeutic approaches to tackle gene defects

On 15th April is the 1st International Pompe Disease Day, a campaign to raise awareness of this rare but severe gene defect. Pompe Disease is only one of more than 40 metabolic disorders that mainly affect children under the age of 10, often with devastating consequences.

15 Apr 2014

Lin28 gene may hold clues to regeneration of damaged kidneys in adults

Nearly one-third of cases of Wilms tumor, a pediatric cancer of the kidney, are linked to a gene called Lin28, according to research from Boston Children's Hospital. Mice engineered to express Lin28 in their kidneys developed Wilms tumor, which regressed when Lin28 was withdrawn, indicating that strategies aimed at blocking or deactivating the gene hold therapeutic promise for children with Wilms.

15 Apr 2014

Scientists receive grant from Biogen Idec to study everyday activities in MS using actual reality

John DeLuca, PhD, and Yael Goverover, PhD, OT, have received a grant from Biogen Idec to study how persons with multiple sclerosis (MS) perform everyday life tasks. The grant, entitled "The Use of Actual Reality to Measure Everyday Life Functional Activity in Multiple Sclerosis" provides financial support to conduct this research.

15 Apr 2014

1/4 human tumor exist genetic polymorphisms linked with increased risk of cancer

In 10% of human tumors there is a family history of hereditary disease associated with mutations in identified genes. The best examples are the cases of polyps in the large intestine associated with the APC gene and breast cancer associated with BRCA1 and BRCA2 genes.

11 Apr 2014

Study confirms neurobiological origin of attention-deficit disorder

A study, carried out on mice, has just confirmed the neurobiological origin of attention-deficit disorder (ADD), a syndrome whose causes are poorly understood. Researchers from CNRS, the University of Strasbourg and INSERM1 have identified a cerebral structure, the superior colliculus, where hyperstimulation causes behavior modifications similar to those of some patients who suffer from ADD.

11 Apr 2014

Impax resubmits NDA for RYTARY providing updated safety and stability information

Impax Pharmaceuticals, a division of Impax Laboratories, Inc. (NASDAQ: IPXL), announced today the resubmission of Impax's New Drug Application (NDA) for RYTARY (IPX066) to the U.S. Food and Drug Administration (FDA).

11 Apr 2014

ICB International develops tracer for imaging alpha-synuclein in Parkinson's disease

On March 4, 2014, ICB International, Inc., ("ICBI"), announced the development of a tracer for imaging alpha-synuclein (a-Syn) in Parkinson's-like mice at the Keystone Symposium for Parkinson disease (PD) in Keystone,Colorado.

11 Apr 2014

Tau Therapeutics presents data of T-type calcium channel inhibitors in treatment of pancreatic cancer

Tau Therapeutics LLC announced today that its academic collaborator, University of Virginia Professor Todd Bauer, MD, presented data at the 105th Annual Meeting of the American Association for Cancer Research (AACR), the premier cancer research event held in San Diego, California from April 5-9.

11 Apr 2014

Researchers identify eight new active molecules against Alzheimer

Researchers of the Unit of Medicine Design and Molecular Topology (Department of Physics Chemistry) of the University of Valencia have discovered eight new active molecules against Alzheimer by a novel mechanism of action, different to the currently used medicines. The work has just been published in the "Plos One" magazine.

11 Apr 2014

Study suggests nestin+ cholinergic neurons may have closer connection to olfactory bulb neurons

Dr. Yuhong Zhao and co-workers from Sun Yat-sen University in China explored the projection of nestin+ neurons to the olfactory bulb and the time course of nestin+ neurons in the medial septum-diagonal band of Broca in adult rats during injury recovery after olfactory nerve transection.

11 Apr 2014

Researchers uncover new aspect of autism

A team of researchers from the University of California, San Diego School of Medicine and the Center for Cancer Systems Biology at the Dana-Farber Cancer Institute has uncovered a new aspect of autism, revealing that proteins involved in autism interact with many more partners than previously known. These interactions had not been detected earlier because they involve alternatively spliced forms of autism genes found in the brain.

11 Apr 2014

Scientists shed light on runny nose

Scientists at the University of Colorado School of Medicine have shed light on one of the most common of ailments - the runny nose.

11 Apr 2014

Loyola study reports link between overuse injury rates and socioeconomic status in young athletes

A Loyola University Medical Center study is reporting for the first time a link between overuse injury rates in young athletes and their socioeconomic status.

11 Apr 2014

Researchers discover tumor suppressor gene folliculin essential to normal lung function in BHD patients

Researchers at Penn Medicine have discovered that the tumor suppressor gene folliculin (FLCN) is essential to normal lung function in patients with the rare disease Birt-Hogg-Dube (BHD) syndrome, a genetic disorder that affects the lungs, skin and kidneys.

11 Apr 2014

Cognitive impairment common among seniors living in nursing homes and community

More than 70% of elderly Medicare beneficiaries experience cognitive impairment or severe dementia near the end-of-life and may need surrogate decision makers for healthcare decisions. Advance care planning for older adults with dementia may be particularly important for individuals who do not reside in a nursing home or a long-term care facility, according to an article published in the April issue of Health Affairs.

11 Apr 2014

Researchers reveal why Peel has one of highest rates of diabetes in Ontario

According to researchers at St. Michael's Hospital, there are two significant reasons why Peel has one of the highest rates of diabetes in Ontario: neighbourhood design that discourages walking and a population with many residents whose ethnic backgrounds predispose them to diabetes.

11 Apr 2014

Adoptive T-cell therapy may help in treating liver cancer, says study

Significant new data presented today at the International Liver Congress- 2014 indicate that liver cancer (Hepatocellular Carcinoma (HCC)) may be treated by adoptive T-cell therapy.

11 Apr 2014

Targeting enzyme responsible for glucose metabolism halts tumor growth, say researchers

Cancer cells generate energy differently than normal cells, a characteristic that helps them to survive and metastasize. A major goal in the field of cancer metabolism is to find ways to overcome this survival advantage.

11 Apr 2014

Medical Condition News

Scientists uncover mechanism and possible treatment to reverse immune suppression in liver disease patients

UK study finds link between low vitamin D status and non-alcoholic fatty liver disease in British children

European scientists set up new therapeutic approaches to tackle gene defects

Lin28 gene may hold clues to regeneration of damaged kidneys in adults

Scientists receive grant from Biogen Idec to study everyday activities in MS using actual reality

1/4 human tumor exist genetic polymorphisms linked with increased risk of cancer

Study confirms neurobiological origin of attention-deficit disorder

Impax resubmits NDA for RYTARY providing updated safety and stability information

ICB International develops tracer for imaging alpha-synuclein in Parkinson's disease

Tau Therapeutics presents data of T-type calcium channel inhibitors in treatment of pancreatic cancer

Researchers identify eight new active molecules against Alzheimer

Study suggests nestin+ cholinergic neurons may have closer connection to olfactory bulb neurons

Researchers uncover new aspect of autism

Scientists shed light on runny nose

Loyola study reports link between overuse injury rates and socioeconomic status in young athletes

Researchers discover tumor suppressor gene folliculin essential to normal lung function in BHD patients

Cognitive impairment common among seniors living in nursing homes and community

Researchers reveal why Peel has one of highest rates of diabetes in Ontario

Adoptive T-cell therapy may help in treating liver cancer, says study

Targeting enzyme responsible for glucose metabolism halts tumor growth, say researchers

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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