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BloodCenter's Erythroid Chimerism test available to monitor transplanted SCD patients

BloodCenter of Wisconsin's Diagnostic Laboratories today announced the availability of an innovative Erythroid Chimerism test to monitor erythroid lineage chimerism in patients with sickle cell disease (SCD) following allogeneic bone marrow transplantation.

28 Aug 2014

Amgen seeks FDA approval for evolocumab to treat patients with high cholesterol

Amgen today announced the submission of a Biologics License Application (BLA) to the U.S. Food and Drug Administration for evolocumab seeking approval for the treatment of high cholesterol.

28 Aug 2014

Cancer patients require better treatment for depression

Findings from three research studies have shown that around three quarters of cancer patients who suffer from major depression do not receive treatment for their depression and that a newly developed medical programme has proven more effective than standard care at reducing depression in these patients.

28 Aug 2014

Many people with severe rheumatoid arthritis failing to take expensive medication

Large numbers of people with severe rheumatoid arthritis are failing to take expensive medication as prescribed, according to a new multi-centre study led by researchers in Manchester.

From The University of Manchester 28 Aug 2014

Merz Pharmaceuticals launches new CAIDE Dementia Risk App

The CAIDE Dementia Risk App from Merz Pharmaceuticals is available free of charge for people from 40 to 65 to calculate their individual risk for getting dementia within the next two decades. Using a traffic light color scheme, the App can also help physicians discuss preventive measures with patients at risk.

28 Aug 2014

Simple colour test could detect early onset of nAMD in the UK

A simple colour test that could detect the early onset of a condition which accounts for over half of visual impairment certifications in the UK is being researched by scientists at Aston University.

28 Aug 2014

Findings could lead to improved treatments for stroke, other brain injuries

Learning a new skill is easier when it is related to ability that we already possess. For example, a trained pianist might learn a new melody more easily than learning how to hit a tennis serve.

28 Aug 2014

Isis Pharmaceuticals begins ISIS-APOCIIIRx Phase 3 study in FCS patients

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 3 study evaluating ISIS-APOCIIIRx in patients with familial chylomicronemia syndrome (FCS). FCS is a rare orphan disease, characterized by extremely high triglyceride levels, that affects an estimated 3,000 to 5,000 patients worldwide.

28 Aug 2014

Scientists explore ways to personalise radiotherapy dose given to lung cancer patients

Manchester scientists are working out how to safely increase the radiotherapy dose given to lung cancer patients - potentially offering improved local control and survival.

From The University of Manchester 28 Aug 2014

New biomarker may improve diagnosis of early-stage rheumatoid arthritis

A novel biomarker for rheumatoid arthritis (RA) has significant potential to help physicians better identify early-stage disease, when treatment can often arrest further disease progression and disability, according to a new study in The Journal of Rheumatology.

From Quest Diagnostics 28 Aug 2014

Patients with intestinal polyps have lower risk of dying from cancer

Patients with intestinal polyps have a lower risk of dying from cancer than previously thought, according to Norwegian researchers.

28 Aug 2014

Young adults who experienced depression have hyper-connected networks in the brain

Depression may be better predicted and understood now that University of Illinois at Chicago researchers have discovered that young adults who previously experienced the mental illness have hyper-connected emotional and cognitive networks in the brain.

28 Aug 2014

New MS treatment found safe, tolerable in phase I clinical trials

A new treatment under investigation for multiple sclerosis (MS) is safe and tolerable in phase I clinical trials, according to a study published August 27, 2014, in Neurology Neuroimmunology & Neuroinflammation, a new online-only, freely accessible, specialty medical journal.

28 Aug 2014

New UCLA study finds that oxidized lipids may also contribute to pulmonary hypertension

Oxidized lipids are known to play a key role in inflaming blood vessels and hardening arteries, which causes diseases like atherosclerosis. A new study at UCLA demonstrates that they may also contribute to pulmonary hypertension, a serious lung disease that narrows the small blood vessels in the lungs.

28 Aug 2014

New evidence puts into doubt the long-held depression belief

New evidence puts into doubt the long-standing belief that a deficiency in serotonin - a chemical messenger in the brain - plays a central role in depression. In the journal ACS Chemical Neuroscience, scientists report that mice lacking the ability to make serotonin in their brains (and thus should have been "depressed" by conventional wisdom) did not show depression-like symptoms.

28 Aug 2014

Experimental drug shows promise as viable treatment for anemia of inflammation

An experimental drug designed to help regulate the blood's iron supply shows promise as a viable first treatment for anemia of inflammation, according to results from the first human study of the treatment published online today in Blood, the Journal of the American Society of Hematology.

28 Aug 2014

Advanced statistical approach evaluates gene-environmental interactions that contribute to disease

Dartmouth cancer researchers developed and tested an advanced statistical model to evaluate the genetic and environmental interactions that contribute to disease as published yesterday in Human Genetics.

28 Aug 2014

HSP90 suggested as potential therapeutic target in PD

Heat shock protein (HSP90) has been suggested to be involved in neuronal protein misfolding and accumulation in Parkinson's disease (PD) brains leading to dopaminergic neuronal death and the eventual dopamine depletion.

28 Aug 2014

Receiving prescription at discharge improves outcomes in stroke patients

Stroke patients are 70 per cent more likely to continue taking their stroke prevention medications one year later if they have a prescription in hand when discharged - according to researchers at St. Michael's Hospital and the Institute for Clinical Evaluative Sciences.

28 Aug 2014

THC may slow or halt progression of Alzheimer's disease

Extremely low levels of the compound in marijuana known as delta-9-tetrahydrocannabinol, or THC, may slow or halt the progression of Alzheimer's disease, a recent study from neuroscientists at the University of South Florida shows.

28 Aug 2014