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Capsule endoscopy could identify presence of "occult" blood at very low levels

A tiny capsule that can carry out a chemical analysis of the contents of one's stomach could identify the presence of so-called "occult" blood at very low levels. The data is automatically broadcast to an external monitoring device for detection of early stage stomach cancer by one's physician. Details of the invention and initial trials are described in a forthcoming issue of the International Journal of Biomedical Engineering and Technology.

5 Dec 2013

Long-term ECG may help patients suffering from chronic cardiac insufficiency

Patients suffering from cardiac diseases may rapidly become emergencies. Then, seconds decide about life and death. However, many cardiac diseases are announced several months before. Symptoms are simply overlooked. A long-term ECG may help. A sensor belt developed at KIT for the first time allows to document cardiac activity of a patient over a long term all around the clock for up to six months. The sensor belt is now presented by the researchers at the Medica trade fair in Düsseldorf.

5 Dec 2013

St. Jude Medical evaluates effectiveness of PNfS and SCS for chronic low back and leg pain

St. Jude Medical, Inc., a global medical device company, has launched a clinical study to evaluate the combination of peripheral nerve field stimulation, and spinal cord stimulation, to determine whether the two therapies together offer more effective management of chronic low back and leg pain than SCS alone. The first patient in the SENSE Subcutaneous and Epidural Neuromodulation System Evaluation study was enrolled by Dr. Thomas Yearwood, an interventional pain physician at Comprehensive Pain & Rehabilitation in Pascagoula, Miss.

5 Dec 2013

New study provides novel stem cell based, tissue engineered construct which can repair damaged bone

Researchers at the Department of Orthopaedics, of the Second Affiliated Hospital of Xi'an Jiaotong University Health Science Center, led by Dr. Kunzheng Wang and Dr. Pei Yang have developed a novel biomimetic tissue engineered bone graft based on rabbit adipose derived stem cells (rASCs), collagen I and a porous beta-tricalcium phosphate (β-TCP) scaffold.

5 Dec 2013

Neurosurgery in Parkinson's disease: Social adjustment, quality of life and coping strategies

Subthalamic nucleus deep brain stimulation can significantly improve the motor features of the Parkinson's disease in carefully selected patients. However, effects of subthalamic nucleus deep brain stimulation on the social adjustment, coping strategies and mental health-related quality of life of these patients remain unclear.

5 Dec 2013

Study: Social ties more important than biological development as predictors of teen sleep behaviors

Medical researchers point to developmental factors, specifically the decline of the sleep-inducing hormone melatonin, as an explanation for why children get less sleep as they become teenagers.

5 Dec 2013

B2G2 component of grape seed extract induces apoptosis in prostate cancer cells

A University of Colorado Cancer Center study published online ahead of print in the journal Nutrition and Cancer describes the laboratory synthesis of the most active component of grape seed extract, B2G2, and shows this synthesized compound induces the cell death known as apoptosis in prostate cancer cells while leaving healthy cells unharmed.

5 Dec 2013

Archimedes Model simulation suggests genetic screening for breast cancer risk can reduce deaths

Archimedes Inc., a healthcare modeling and analytics company, today announced results of a simulated clinical trial which found that the seven single-nucleotide polymorphisms (7SNP) genetic test for breast cancer was most cost effective when used to guide MRI screenings for patients found to have an intermediate lifetime risk of developing the disease.

5 Dec 2013

UCSB researcher tracks source of E280A gene mutation responsible for early-onset Alzheimer's

The age and origin of the E280A gene mutation responsible for early-onset Alzheimer's in a Colombian family with an unusually high incidence of the disease has been traced to a single founder dating from the 16th century.

5 Dec 2013

Study reveals nearly 1 in every 100 anesthesiologist developed substance use disorder during training

According to a study conducted by Mayo Clinic and the American Board of Anesthesiology (ABA), nearly 1 in every 100 anesthesiology residents entering primary training from 1975 to 2009 developed substance use disorder (SUD) during training.

5 Dec 2013

New evidence-based guidelines for diagnosis and assessment of atopic dermatitis

The American Academy of Dermatology (Academy) has released new evidence-based guidelines for the diagnosis and assessment of atopic dermatitis based on an extensive review of the scientific literature on this chronic skin condition characterized by itchy red patches of skin.

5 Dec 2013

TB vaccine may help prevent multiple sclerosis

A vaccine used to prevent tuberculosis in other parts of the world may help prevent multiple sclerosis in people who show the beginning signs of the disease, according to a new study published in the December 4, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

5 Dec 2013

Scientists receive $4M grant to identify biomarker for secondary injuries associated with brain

In an effort to lower medical costs, identify patients at risk for injury, and speed patient recovery, scientists will attempt to identify a molecular signal that indicates severity of brain-injury during a $4 million, five-year federal grant to Barrow Neurological Institute at St. Joseph's Hospital and Medical Center, Phoenix Children's Hospital and the Translational Genomics Research Institute (TGen).

5 Dec 2013

Senesco completes cohort 3 of SNS01-T Phase 1b/2a trial for multiple myeloma and lymphoma treatment

Senesco Technologies, Inc. reported today the completion of cohort 3 of its Phase 1b/2a clinical trial for its drug, SNS01-T, for the treatment of multiple myeloma and lymphoma. The Company has also received approval from its Data Review Committee to proceed to cohort 4, which is expected to require six evaluable patients.

5 Dec 2013

Enrollment opens for IMO-8400 Phase 1/2 trial in patients with Waldenström's macroglobulinemia

Idera Pharmaceuticals, Inc., a clinical stage biopharmaceutical company developing a novel therapeutic approach for the treatment of autoimmune diseases and genetically defined forms of B-cell lymphoma, today announced that enrollment is open for a Phase 1/2 clinical trial of IMO-8400 in patients with Waldenström's macroglobulinemia, following acceptance of its Investigational New Drug application by the U.S. Food and Drug Administration.

5 Dec 2013

Poor sleep quality linked with mood disturbance and lower quality of life in people with obesity

A new study shows that poor sleep quality is strongly associated with mood disturbance and lower quality of life among people with extreme obesity.

5 Dec 2013

New research offers fresh insights to drug designers searching for better pain treatments

In a technical tour de force, UC San Francisco scientists have determined, at near-atomic resolution, the structure of a protein that plays a central role in the perception of pain and heat.

5 Dec 2013

Mothers, but not fathers, exhibit symptoms of depression after the death of adult son

Mothers - but not fathers - exhibited symptoms of depression and experienced declines in overall health after the death of an adult son, while the death of a daughter had no such effect on either parent, according to one of the first studies to examine the impacts of the death of an adult child on parents aged 65 and older.

5 Dec 2013

Blocking Cdh1 protein could accelerate development of new therapies targeting cancer

The laboratory of Marcos Malumbres, who is head of the Spanish National Cancer Research Centre's (CNIO) Cell Division & Cancer Group, working alongside Isabel Fari-as' team from the University of Valencia, shows, in a study published today in the journal Nature Communications, how in mice the elimination of the Cdh1 protein -a sub-unit of the APC/C complex, involved in the control of cell division-prevents cellular proliferation of rapidly dividing cells.

5 Dec 2013

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

The first study of its kind, led by Melinda Sothern, PhD, CEP, Professor and Director of Behavioral and Community Health Sciences at LSU Health Sciences Center New Orleans School of Public Health, reveals that the same pro-inflammatory proteins linked to obesity and the metabolic syndrome in adults appear to protect children prior to puberty.

4 Dec 2013

Medical Condition News

Capsule endoscopy could identify presence of "occult" blood at very low levels

Long-term ECG may help patients suffering from chronic cardiac insufficiency

St. Jude Medical evaluates effectiveness of PNfS and SCS for chronic low back and leg pain

New study provides novel stem cell based, tissue engineered construct which can repair damaged bone

Neurosurgery in Parkinson's disease: Social adjustment, quality of life and coping strategies

Study: Social ties more important than biological development as predictors of teen sleep behaviors

B2G2 component of grape seed extract induces apoptosis in prostate cancer cells

Archimedes Model simulation suggests genetic screening for breast cancer risk can reduce deaths

UCSB researcher tracks source of E280A gene mutation responsible for early-onset Alzheimer's

Study reveals nearly 1 in every 100 anesthesiologist developed substance use disorder during training

New evidence-based guidelines for diagnosis and assessment of atopic dermatitis

TB vaccine may help prevent multiple sclerosis

Scientists receive $4M grant to identify biomarker for secondary injuries associated with brain

Senesco completes cohort 3 of SNS01-T Phase 1b/2a trial for multiple myeloma and lymphoma treatment

Enrollment opens for IMO-8400 Phase 1/2 trial in patients with Waldenström's macroglobulinemia

Poor sleep quality linked with mood disturbance and lower quality of life in people with obesity

New research offers fresh insights to drug designers searching for better pain treatments

Mothers, but not fathers, exhibit symptoms of depression after the death of adult son

Blocking Cdh1 protein could accelerate development of new therapies targeting cancer

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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