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Some people experience worse cholesterol levels during colder months

Cholesterol levels fluctuate based on the time of year with more unfavorable lipid profiles seen in the colder months, a trend that may be driven by related behavior changes, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

'Mini heart' invented to aid blood flow through venous segments

George Washington University researcher Narine Sarvazyan, Ph.D., has invented a new organ to help return blood flow from veins lacking functional valves. A rhythmically contracting cuff made of cardiac muscle cells surrounds the vein acting as a 'mini heart' to aid blood flow through venous segments. The cuff can be made of a patient's own adult stem cells, eliminating the chance of implant rejection.

28 Mar 2014

IRB researchers identify dual role of p38 protein in colon cancer

A team headed by Angel R. Nebreda at the Institute for Research in Biomedicine identifies a dual role of the p38 protein in colon cancer. The study demonstrates that, on the one hand, p38 is important for the optimal maintenance of the epithelial barrier that protects the intestine against toxic agents, thus contributing to decreased tumour development.

28 Mar 2014

Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

Novartis today announced that The New England Journal of Medicine (NEJM) published clinical trial results showing the investigational compound LDK378 (ceritinib) achieved an overall response rate (ORR, including complete response [CR] and partial response [PR]) of 58% and a median progression-free survival (PFS) of seven months in adults with advanced anaplastic lymphoma kinase positive (ALK+) non-small cell lung cancer (NSCLC) who received 400 mg or higher of LDK378 per day.

28 Mar 2014

Discovery could lead to new medications for cancer, say Rice University scientists

A new understanding of proteins at the nexus of a cell's decision to survive or die has implications for researchers who study cancer and age-related diseases, according to biophysicists at the Rice University-based Center for Theoretical Biological Physics.

28 Mar 2014

Heart failure patients benefit from new device till transplant

The largest single-center study of patients implanted with a total artificial heart finds the device may help patients in severe heart failure survive until they can receive a heart transplant, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

Jackson Lab professor wins nearly $2M grant for investigating role of noncoding RNAs in cancer

The National Cancer Institute has awarded a three-year grant totaling $2,168,535 to Professor Yijun Ruan, Ph.D., of The Jackson Laboratory for Genomic Medicine, for his research into the role of noncoding RNAs in cancer and other diseases.

28 Mar 2014

Scientists identify two markers that predict patient's resistance to radiation therapy for cancer

An international team of researchers, led by Beaumont Health System's Jan Akervall, M.D., Ph.D., looked at biomarkers to determine the effectiveness of radiation treatments for patients with squamous cell cancer of the head and neck.

28 Mar 2014

Study links broken heart syndrome to natural disasters

Dramatic spikes in cases of Takotsubo cardiomyopathy, also called broken heart syndrome, were found in two states after major natural disasters, suggesting the stress of disasters as a likely trigger, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

Researchers review influence of lipid rafts on progression of Alzheimer's disease

Research over decades has implicated aberrant autophagy and lysosomal function as reliable markers and therapeutic targets for neurodegenerative diseases.

27 Mar 2014

Study: Overweight and obese teenagers have higher risk of death before age 50

Although people live longer today than they did 50 years ago, people who were overweight and obese as teenagers aren't experiencing the same gains as other segments of the population, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

27 Mar 2014

Schizophrenia Research: Cognition, an online open access journal from Elsevier

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced the launch of Schizophrenia Research: Cognition, a new open access journal dedicated to publishing original research, concise research reports, brief reports, letters to the editor, and review papers addressing the role of cognitive functioning in schizophrenia.

27 Mar 2014

FDA accepts AVP-825 NDA for acute treatment of migraine

The U.S. Food and Drug Administration has accepted the New Drug Application (NDA) for AVP-825, an innovative closed-palate Breath Powered investigational drug-device combination product for the acute treatment of migraine.

27 Mar 2014

Cardiovascular disease related deaths drop after implementation of public smoking ban

A new study on the impact of Michigan's statewide smoking ban adds to mounting evidence that policies prohibiting tobacco smoking in workplaces and other public spaces may substantially improve public health by reducing heart disease and death, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

27 Mar 2014

Marathon training associated with improved risk factors related to cardiovascular disease

Marathon training is associated with improved risk factors related to cardiovascular disease among middle-aged recreational male runners, suggesting that race preparation may be an effective strategy for reducing heart disease risk, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

27 Mar 2014

Research: Mediterranean diet linked to lower risk of diabetes

Adoption of a Mediterranean diet is linked to a lower risk of diabetes, especially among people at high risk for cardiovascular disease, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

27 Mar 2014

Study to understand how protein motor works for development of targeted cancer therapies

Researchers at Warwick Medical School have shown for the first time how a protein motor, Kif15, uses acrobatic flexibility to navigate within the mitotic spindle. Understanding how it works could prove vital for the development of targeted cancer therapies.

27 Mar 2014

National MS Society invests $29M to support new MS research projects, training awards

The National Multiple Sclerosis Society has committed another $29 million to support an expected 83 new MS research projects and training awards.

27 Mar 2014

Senhwa Biosciences to present CX-5461 study results at AACR meeting

Senhwa Biosciences, Inc. announced today that results from research with its first-in-class Pol I inhibitor, CX-5461, will be presented at the 2014 American Association for Cancer Research (AACR) annual meeting held on April 5-9 in San Diego, CA.

27 Mar 2014

Researchers discover new way of giving people sweet dreams

Today psychologist Professor Richard Wiseman from the University of Hertfordshire announces the results of a two-year study into dream control. The experiment shows that it is now possible for people to create their perfect dream, and so wake up feeling especially happy and refreshed.

27 Mar 2014

Medical Condition News

Some people experience worse cholesterol levels during colder months

'Mini heart' invented to aid blood flow through venous segments

IRB researchers identify dual role of p38 protein in colon cancer

Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

Discovery could lead to new medications for cancer, say Rice University scientists

Heart failure patients benefit from new device till transplant

Jackson Lab professor wins nearly $2M grant for investigating role of noncoding RNAs in cancer

Scientists identify two markers that predict patient's resistance to radiation therapy for cancer

Study links broken heart syndrome to natural disasters

Researchers review influence of lipid rafts on progression of Alzheimer's disease

Study: Overweight and obese teenagers have higher risk of death before age 50

Schizophrenia Research: Cognition, an online open access journal from Elsevier

FDA accepts AVP-825 NDA for acute treatment of migraine

Cardiovascular disease related deaths drop after implementation of public smoking ban

Marathon training associated with improved risk factors related to cardiovascular disease

Research: Mediterranean diet linked to lower risk of diabetes

Study to understand how protein motor works for development of targeted cancer therapies

National MS Society invests $29M to support new MS research projects, training awards

Senhwa Biosciences to present CX-5461 study results at AACR meeting

Researchers discover new way of giving people sweet dreams

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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