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Alcohol use disorders contribute more significantly to disease burden

Disorders related to the abuse of alcohol contribute significantly to the burden of disease in the U.S., finds a new study in Alcoholism: Clinical and Experimental Research. Researchers estimated that in 2005, about 53,000 men and 12,000 women died from issues related to alcohol use disorders.

27 Nov 2013

Study links genetic predisposition to childhood obesity

Research has suggested that a particular gene in the brain's reward system contributes to overeating and obesity in adults. This same variant has now been linked to childhood obesity and tasty food choices, particularly for girls, according to a new study by Dr. Patricia Silveira and Prof. Michael Meaney of McGill University and Dr. Robert Levitan of the University of Toronto.

27 Nov 2013

African Americans have double the risk of end-stage renal disease compared to white Americans

In the United States, African Americans have approximately twice the risk of end-stage renal disease compared to white Americans, despite a similar prevalence in earlier stages of chronic kidney disease. A large study co-authored by George Washington University researcher Dominic Raj, M.D., identifies factors that mediate differences in the progression of chronic kidney disease between black patients and white patients, as well as among black patients, in order to reduce the excess burden of end-stage renal disease and its complications in black patients.

27 Nov 2013

Survivors of hematopoietic stem cell transplant benefit from expressive helping

A new study finds that survivors of hematopoietic stem cell transplant, an aggressive treatment for blood cancers, benefited from a two-part peer support process the authors call expressive helping.

27 Nov 2013

Freiburg scientists discover substance that suppresses unchecked cell division in leukemia cells

Scientists of the University of Freiburg and the Freiburg University Medical Center from the collaborative research center Medical Epigenetics (SFB 992) have discovered a new active substance that inhibits cell division in leukemia cells and could play an important role in the fight against cancer.

27 Nov 2013

Women who test negative for family-specific BRCA2 mutations may have four times risk for breast cancer

Women who are members of families with BRCA2 mutations but who test negative for the family-specific BRCA2 mutations are still at greater risk for developing breast cancer compared with women in the general population, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

27 Nov 2013

CSHL identifies specific stretch of DNA that helps cancerous blood cells to proliferate in AML

A team of researchers at Cold Spring Harbor Laboratory (CSHL) has identified a leukemia-specific stretch of DNA called an enhancer element that enables cancerous blood cells to proliferate in Acute Myeloid Leukemia (AML), a devastating cancer that is incurable in 70% of patients.

27 Nov 2013

FDA accepts Purdue Pharma's Targiniq ER Tablets CII NDA for review

Purdue Pharma L.P. today announced that the U.S. Food and Drug Administration has accepted for review a New Drug Application for Targiniq ER (oxycodone HCl/naloxone HCl controlled-release) Tablets CII, for the management of chronic pain.

27 Nov 2013

Study shows dl-3n-butylphthalide may have protective effects against diffuse brain injury

Dl-3n-butylphthalide can effectively treat cerebral ischemia; however, the mechanisms underlying the effects of dl-3n-butylphthalide on microcirculation disorders following diffuse brain injury remain unclear.

27 Nov 2013

International researchers report significant findings on vascular abnormality outside the brain

Studies on Alzheimer's disease and other forms of dementia have long focused on what's happening inside the brain. Now an international research team studying Alzheimer's and mild cognitive impairment is reporting potentially significant findings on a vascular abnormality outside the brain.

27 Nov 2013

Research: Human neural stem cells could improve blood flow in critical limb ischemia

New research has shown human neural stem cells could improve blood flow in critical limb ischemia through the growth of new vessels. Critical limb ischemia is a disease that severely obstructs arteries and reduces the blood flow to legs and feet. CLI remains an unmet clinical problem and with an ageing population and the rise in type II diabetes, the incidence of CLI is expected to increase.

27 Nov 2013

Biochemist receives grant to identify pathway to regulate DNA damage repair in cancer cells

Chemotherapy and radiation therapy are often used to kill cancer cells by causing irreparable DNA damage. However, some cancer patients resist chemotherapy and radiation due to a highly active DNA damage repair system.

26 Nov 2013

Researchers find that hay fever and allergies make migraines worse

People with migraine who also battle allergies and hay fever (rhinitis) endure a more severe form of headaches than their peers who struggle with migraine, but aren't affected by the seasonal or year-round sniffles, according to researchers from the University of Cincinnati, Montefiore Medical Center and the Albert Einstein College of Medicine of Yeshiva University and Vedanta Research.

26 Nov 2013

High-fat food consumption during puberty may increase the risk of breast cancer

New findings show that eating a high-fat diet beginning at puberty speeds up the development of breast cancer and may actually increase the risk of cancer similar to a type often found in younger adult women.

26 Nov 2013

UK researchers identify a gene that regulates alcohol consumption

UK researchers have discovered a gene that regulates alcohol consumption and when faulty can cause excessive drinking. They have also identified the mechanism underlying this phenomenon.

26 Nov 2013

Researchers develop new microsystem for testing drugs to treat epilepsy, MG and cystic fibrosis

Researchers from the University of Southampton, in collaboration with researchers at the University of Quebec at Montreal, have developed a new microsystem for more efficient testing of pharmaceutical drugs to treat diseases such as cystic fibrosis, MG (myasthenia gravis) and epilepsy.

26 Nov 2013

Auditory processing disorder diagnosis: an interview with Dr Doris-Eva Bamiou, UCL Ear Institute

It is a listening or hearing disorder, which is due to the brain’s defective analysis of sounds, so that individuals who are affected with this disorder cannot make sense of what they hear.

26 Nov 2013

SIMM and Crown Bioscience collaborate to build MCT center in China

Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences (CAS) and Crown Bioscience, Inc., announced today that they have reached an agreement to form a strategic collaboration focused on translational oncology and to join forces to build a mouse clinical trial (MCT) center at Crown Taicang campus, Taicang, Jiangsu province, China --SIMM-Crown Mouse Clinical Trial Center, or SCMC.

26 Nov 2013

Researchers successfully target T lymphocytes which play key role in body's immune response

Researchers at the University of California, San Diego School of Medicine have successfully targeted T lymphocytes - which play a central role in the body's immune response - with another type of white blood cell engineered to synthesize and deliver bits of non-coding RNA or microRNA (miRNA).

26 Nov 2013

Alternative treatment for autism focuses on controlling the 'fight or flight' response

A novel approach to treating children diagnosed with autism spectrum disorder could help them navigate their world by teaching them to turn their symptoms into strengths.

26 Nov 2013

Medical Condition News

Alcohol use disorders contribute more significantly to disease burden

Study links genetic predisposition to childhood obesity

African Americans have double the risk of end-stage renal disease compared to white Americans

Survivors of hematopoietic stem cell transplant benefit from expressive helping

Freiburg scientists discover substance that suppresses unchecked cell division in leukemia cells

Women who test negative for family-specific BRCA2 mutations may have four times risk for breast cancer

CSHL identifies specific stretch of DNA that helps cancerous blood cells to proliferate in AML

FDA accepts Purdue Pharma's Targiniq ER Tablets CII NDA for review

Study shows dl-3n-butylphthalide may have protective effects against diffuse brain injury

International researchers report significant findings on vascular abnormality outside the brain

Research: Human neural stem cells could improve blood flow in critical limb ischemia

Biochemist receives grant to identify pathway to regulate DNA damage repair in cancer cells

Researchers find that hay fever and allergies make migraines worse

High-fat food consumption during puberty may increase the risk of breast cancer

UK researchers identify a gene that regulates alcohol consumption

Researchers develop new microsystem for testing drugs to treat epilepsy, MG and cystic fibrosis

Auditory processing disorder diagnosis: an interview with Dr Doris-Eva Bamiou, UCL Ear Institute

SIMM and Crown Bioscience collaborate to build MCT center in China

Researchers successfully target T lymphocytes which play key role in body's immune response

Alternative treatment for autism focuses on controlling the 'fight or flight' response

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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