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Researchers identify enzymes that are crucial for growth of cancers with genetic aberrations in p53

The most frequently mutated gene across all types of cancers is a gene called p53. Unfortunately it has been difficult to directly target this gene with drugs. Now a multi-institutional research team, led by Dr. Lewis Cantley and investigators at Weill Cornell Medical College, has identified a family of enzymes they say is crucial for the growth of cancers that have genetic aberrations in p53.

8 Nov 2013

Lactoferricin B25 derived from cow's milk shows promise for treatment of gastric cancer

New research from a team of researchers in Taiwan indicates that a peptide fragment derived from cow's milk, known as lactoferricin B25 (LFcinB25), exhibited potent anticancer capability against human stomach cancer cell cultures.

8 Nov 2013

Vitamin C can improve skeletal muscle fatigue in COPD patients

Chronic obstructive pulmonary disease—a health problem in which the lungs lose their inherent springiness, making it progressively harder to breathe—can have a dramatic effect on the ability to exercise and even perform simple activities of daily life because of the disease's fallout effects on skeletal muscles.

8 Nov 2013

Aerobic exercise may be superior to resistance exercise for obese teen girls

Obesity has more than doubled in children and tripled in adolescents in the United States in the past 30 years, according to the Centers for Disease Control and Prevention. The growing rate of childhood obesity is a major health concern since overweight and obese youth are at increased risk of developing several diseases once considered reserved for adults. These new pediatric diseases include type-2 diabetes, metabolic syndrome, and non-alcoholic fatty liver disease, a condition in which fat builds up in the liver, potentially impairing its function over time.

8 Nov 2013

Study investigates association between preterm birth and later retinal detachment

Children born extremely prematurely have up to a 19 times greater risk of retinal detachment later in life than peers born at term, according to a Swedish study published this month in Ophthalmology, the journal of the American Academy of Ophthalmology.

8 Nov 2013

Increased consumption of vegetable protein linked with prolonged survival among kidney disease patients

Increased consumption of vegetable protein was linked with prolonged survival among kidney disease patients in a new a study. The findings will be presented at ASN Kidney Week 2013 November 5-10 at the Georgia World Congress Center in Atlanta, GA.

8 Nov 2013

Consumption of tree nuts inversely associated with risk of pancreatic cancer in women

In a large prospective study published online in the British Journal of Cancer, researchers looked at the association between nut consumption and risk of pancreatic cancer among 75,680 women in the Nurses' Health Study, with no previous history of cancer.

8 Nov 2013

Study finds few beneficial effects of metformin drug for cardiovascular disease in people without diabetes

Despite high expectations for the commonly used diabetes drug metformin to improve risk factors for heart disease in people without diabetes, few beneficial effects have been found in a randomised trial of patients with established cardiovascular disease, published in The Lancet Diabetes & Endocrinology.

7 Nov 2013

NIDDK director to receive Outstanding Achievement Award from NKF

The National Kidney Foundation will honor Dr. Griffin P. Rodgers, Director of the National Institute of Diabetes and Digestive and Kidney Diseases, one of the National Institutes of Health, for his commitment to bettering the lives of patients and raising awareness of chronic kidney disease.

7 Nov 2013

Mental health services, tobacco control programs must work together to encourage smoking cessation

Persons with mental illness account for more than one-third of adult smokers in the United States and despite a decline in tobacco use during the past five decades, there has been no change in the smoking rate for patients with poor mental health.

7 Nov 2013

Inhibition of heart protein reduces damage from heart attack, say researchers

The stop and start of blood flow to the heart during and after a heart attack causes severe damage to heart cells, reducing their capacity to function and potentially causing their death.

7 Nov 2013

Immunocore achieves first milestone in major research and licensing agreement with GSK

Immunocore Limited, the Oxford-based biotechnology company developing novel biological drugs to treat cancer and viral disease, today announced the achievement of its first milestone in its major research and licensing agreement with GlaxoSmithKline for multiple novel targets.

7 Nov 2013

Linagliptin shows efficacy, tolerability in adults with T2D and liver disease

Boehringer Ingelheim and Eli Lilly and Company announce new data that reinforce the efficacy and tolerability of linagliptin in people with Type 2 Diabetes and liver disease, as well as Asian people with T2D aged 65 years or older.

7 Nov 2013

Researchers identify new class of anti-inflammatory drugs may be used to treat IBD

Researchers in UCD Conway Institute and Systems Biology Ireland have identified a way that a new class of anti-inflammatory drugs may be used to treat inflammatory bowel disease (IBD).

7 Nov 2013

Stroke patients treated at hospitals with neurology residency programs benefit from tPA drugs

Stroke patients treated at hospitals with neurology residency programs are significantly more likely to get life-saving clot-busting drugs than those seen at other teaching or non-teaching hospitals, new Johns Hopkins-led research suggests.

7 Nov 2013

Patrys receives FDA Orphan Medicinal Product Designation for PAT-SM6

Patrys Limited, a clinical stage biotechnology company, has received confirmation of Orphan Medicinal Product Designation for its lead anti-cancer product PAT-SM6, from the USA Food and Drugs Administration.

7 Nov 2013

Study: Speaking a second language may delay onset of three types of dementias

In the largest study on the topic to date, research shows that speaking a second language may delay the onset of three types of dementias. The research is published in the November 6, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Nov 2013

MGH researchers identify probable mechanism for pain-induced cognitive impairment

The pain caused by a surgical incision may contribute to the risk of postoperative cognitive dysfunction, a sometimes transient impairment in learning and memory that affects a small but significant number of patients in the days following a surgical procedure.

7 Nov 2013

Simple urine test can help identify disease risks in young type 1 diabetes patients

Using a simple urine test, researchers can now identify young people with type 1 diabetes at risk of heart and kidney disease. The new research, funded by JDRF, Diabetes UK, and the British Heart Foundation, was published today, 06 November, in the journal Diabetes Care.

7 Nov 2013

University of Adelaide research uses special adult stem cells to treat Hurler's syndrome

University of Adelaide research using special adult stem cells is promising new hope for better treatments for the devastating genetic disease Hurler's syndrome.

7 Nov 2013

Medical Condition News

Researchers identify enzymes that are crucial for growth of cancers with genetic aberrations in p53

Lactoferricin B25 derived from cow's milk shows promise for treatment of gastric cancer

Vitamin C can improve skeletal muscle fatigue in COPD patients

Aerobic exercise may be superior to resistance exercise for obese teen girls

Study investigates association between preterm birth and later retinal detachment

Increased consumption of vegetable protein linked with prolonged survival among kidney disease patients

Consumption of tree nuts inversely associated with risk of pancreatic cancer in women

Study finds few beneficial effects of metformin drug for cardiovascular disease in people without diabetes

NIDDK director to receive Outstanding Achievement Award from NKF

Mental health services, tobacco control programs must work together to encourage smoking cessation

Inhibition of heart protein reduces damage from heart attack, say researchers

Immunocore achieves first milestone in major research and licensing agreement with GSK

Linagliptin shows efficacy, tolerability in adults with T2D and liver disease

Researchers identify new class of anti-inflammatory drugs may be used to treat IBD

Stroke patients treated at hospitals with neurology residency programs benefit from tPA drugs

Patrys receives FDA Orphan Medicinal Product Designation for PAT-SM6

Study: Speaking a second language may delay onset of three types of dementias

MGH researchers identify probable mechanism for pain-induced cognitive impairment

Simple urine test can help identify disease risks in young type 1 diabetes patients

University of Adelaide research uses special adult stem cells to treat Hurler's syndrome

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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