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Authors of new paper outline possible factors to identify metabolically healthy obesity

Metabolically healthy obesity – where an individual has a Body Mass Index of greater than 30 but does not appear to be at increased risk of the health complications usually associated with excess weight – has only been recently widely recognised by medical practitioners.

3 Sep 2013

Adhering to MedDi does not appear associated with time to clinical onset of HD

Adhering to a Mediterranean-type diet (MedDi) does not appear associated with the time to clinical onset of Huntington disease (phenoconversion), according to a study by Karen Marder, M.D., M.P.H., of Columbia University College of Physicians and Surgeons, New York, N.Y., and colleagues.

3 Sep 2013

New model to predict which patients are most likely to have severe kidney failure from rhabdomyolysis

Researchers from Brigham and Women's Hospital (BWH) have developed a risk score calculation that can help predict which patients with rhabdomyolysis (a condition that occurs due to muscle damage) may be at risk for the severe complication of kidney failure or death.

3 Sep 2013

PTSD in mothers linked with increased risk for child maltreatment

Posttraumatic stress disorder (PTSD) in mothers appears to be associated with an increased risk for child maltreatment beyond that associated with maternal depression, according to a study published by JAMA Pediatrics, a JAMA Network publication.

3 Sep 2013

Argininosuccinic aciduria (ASA) and gene therapy: an interview with Dr Julien Baruteau, UCL Institute for Women's Health, London

This rare genetic condition can theoretically affect patients at any age but symptoms are more often observed in childhood and even uncommonly during the first days of life.

2 Sep 2013

Study finds reduction in incidence of STEMI after smoking ban implemented in Switzerland

Second-hand smoke increases the risk of coronary artery disease and acute myocardial infarction. For this reason, health policies aimed at reducing tobacco consumption and public smoke exposure are strongly recommended.

2 Sep 2013

Women are 25% less likely to die post TAVI than men, says doctor

Dr Sherif said: "Earlier studies on the impact of gender on outcome after transcatheter aortic valve implantation (TAVI) have had conflicting results. A Canadian study reported in 641 consecutive patients that female sex is associated with a better long-term and short-term survival after TAVI.1 An Italian study of 305 high risk patients found no gender differences in composite safety and efficacy endpoints at 30 days and one year after TAVI."2

2 Sep 2013

TAVI is safe therapeutic option than redo cardiac surgery

Use of bioprosthetic heart valves has dramatically increased (from 18% in 1991 to 59% in 2003), mainly in older patients with comorbidities. This is due to the increased risk of bleeding complications associated with lifelong use of anticoagulation for mechanical prostheses.

2 Sep 2013

NPS MedicineWise reiterates safety messages around newer oral anticoagulants

NPS MedicineWise is reiterating safety messages around the newer anticoagulants dabigatran (Pradaxa) and apixaban (Eliquis) following their PBS listing for preventing stroke on 1 September 2013 – and again for rivaxabaran (Xarelto) which was PBS listed in August for the same purpose.

2 Sep 2013

DE-MRI before ablation can stage atrial fibrosis and help predict success treatment

In patients with atrial fibrillation, delayed enhancement magnetic resonance imaging (DE-MRI) performed before ablative treatment can stage the degree of damaged heart tissue (atrial fibrosis) and help predict whether treatment will be successful or not, according to results of Delayed Enhancement - MRI determinant of successful Catheter Ablation of Atrial Fibrillation (DECAAF) trial.

2 Sep 2013

Low temperature triggers acute myocardial infarction

Professor Claeys said: "Air pollution and temperature changes are the most frequently reported environmental triggers for acute myocardial infarction (AMI). Epidemiologic studies have focused mainly on one environmental condition, but most environmental triggers are related to each other and may attenuate or reinforce the triggering effect of a single environmental factor."

2 Sep 2013

Each daily minute of higher-intensity activity lowers odds of obesity

To win the war against weight gain, it turns out that every skirmish matters - as long as the physical activity puts your heart and lungs to work.

2 Sep 2013

Leisure-time physical activity might reduce risk of SCD among men with low CRF

Dr Laukkanen said: "Sudden cardiac death (SCD) accounts for approximately 50% of deaths from coronary heart disease. SCD typically occurs shortly after the onset of symptoms, leaving little time for effective medical interventions, and most cases occur outside hospital with few or no early warning signs. Finding ways to identify individuals at elevated risk of SCD would allow early interventions on risk factors to be implemented."

2 Sep 2013

Pacemakers implanted for slow heart rhythm restore life expectancy to normal levels

Pacemakers implanted for slow heart rhythm restore life expectancy to normal levels, reveals research presented at ESC Congress 2013 today by Dr Erik O. Udo from the Netherlands. The findings provide a new reference point for the prognosis of modern pacemaker patients.

2 Sep 2013

Average height of European males increased by 11cm between mid-19th century and 1980

The average height of European males increased by an unprecedented 11cm between the mid-nineteenth century and 1980, according to a new paper published online today in the journal Oxford Economic Papers. Contrary to expectations, the study also reveals that average height actually accelerated in the period spanning the two World Wars and the Great Depression.

2 Sep 2013

Being overweight but metabolically healthy is not linked with increased risk of heart attack

Metabolically healthy women have the same cardiovascular disease risk regardless of their BMI, according to research presented at the ESC Congress today by Dr S-ren Sk-tt Andersen and Dr Michelle Schmiegelow from Denmark.

2 Sep 2013

Mass screening programme of 75-76 year olds to identify undiagnosed AF

Stroke is the second cause of death worldwide. Atrial fibrillation is the most common clinically relevant cardiac arrhythmia in Europe, affecting approximately 1.5-2% of the general population.1 Prevalence is estimated to double in the next 50 years as the population ages.

2 Sep 2013

Anti-diabetic drug alogliptin meets primary endpoint in EXAMINE trial

Patients with type 2 diabetes and high cardiovascular risk due to recent acute coronary syndromes had similar rates of cardiovascular events when treated with the anti-diabetic agent alogliptin compared to placebo according to results of the Examination of Cardiovascular Outcomes with Alogliptin versus Standard of Care trial presented at the European Society of Cardiology Congress.

2 Sep 2013

Debiopharm starts Debio 1347 phase I study in patients with advanced solid tumors

Debiopharm Group, the Swiss-based global biopharmaceutical company that focuses on the development of prescription drugs that target unmet medical needs including oncology, today announced the start of a phase I, open label multicenter study of a selective FGFR 1, 2, 3 inhibitor, Debio 1347 (CH5183284) in patients with advanced solid tumors.

2 Sep 2013

Combination of music and exercise training improves endothelial function in CAD patients

Professor Deljanin Ilic said: "In the setting of cardiovascular risk factors and cardiovascular disease the endothelium loses its normal function.1 Since endothelium derived nitric oxide is necessary to maintain an adequate vascular response, correction of endothelial dysfunction has become a goal of therapy."

2 Sep 2013

Medical Condition News

Authors of new paper outline possible factors to identify metabolically healthy obesity

Adhering to MedDi does not appear associated with time to clinical onset of HD

New model to predict which patients are most likely to have severe kidney failure from rhabdomyolysis

PTSD in mothers linked with increased risk for child maltreatment

Argininosuccinic aciduria (ASA) and gene therapy: an interview with Dr Julien Baruteau, UCL Institute for Women's Health, London

Study finds reduction in incidence of STEMI after smoking ban implemented in Switzerland

Women are 25% less likely to die post TAVI than men, says doctor

TAVI is safe therapeutic option than redo cardiac surgery

NPS MedicineWise reiterates safety messages around newer oral anticoagulants

DE-MRI before ablation can stage atrial fibrosis and help predict success treatment

Low temperature triggers acute myocardial infarction

Each daily minute of higher-intensity activity lowers odds of obesity

Leisure-time physical activity might reduce risk of SCD among men with low CRF

Pacemakers implanted for slow heart rhythm restore life expectancy to normal levels

Average height of European males increased by 11cm between mid-19th century and 1980

Being overweight but metabolically healthy is not linked with increased risk of heart attack

Mass screening programme of 75-76 year olds to identify undiagnosed AF

Anti-diabetic drug alogliptin meets primary endpoint in EXAMINE trial

Debiopharm starts Debio 1347 phase I study in patients with advanced solid tumors

Combination of music and exercise training improves endothelial function in CAD patients

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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