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Researchers identify mutation in CNGB1 gene causing PRA in Phalene and Papillon

Professor Hannes Lohi's research group at the University of Helsinki and Folkh-lsan Research Center, Finland, has identified a mutation in CNGB1 gene, causing progressive retinal atrophy (PRA) in the Phalene and Papillon dog breeds.

30 Aug 2013

BP and headache drug effectively speeds up treatment of TB

Infectious disease experts at Johns Hopkins have found, in studies in mice, that a drug better known as a treatment for high blood pressure and headaches effectively speeds up treatment of TB when added to the standard, daily antibiotic regimen. Test animals were cured in four months instead of the usual six.

30 Aug 2013

Scientists unravel how DNA damage may trigger lupus erythematosus

Summer, sun and the sea - a dream vacation for most - can turn sour for those affected by lupus erythematosus. For them, absorption of the UV-light component in sunlight may cause florid inflammation and redness of the skin. Scientists of the University Hospital Bonn, Germany have now discovered which signaling pathway of the innate immune system promotes autoimmune symptoms following sun-induced DNA damage.

30 Aug 2013

Diabetic patients could benefit from breakthrough cell study

Diabetic patients could benefit from a breakthrough that enables scientists to take cells from the pancreas and change their function to produce insulin.

30 Aug 2013

Research team examines link between genetics and memory problems in Parkinson's patients

A research team at University of Virginia School of Medicine led by Matthew Barrett, MD, MSc, will use a state grant to examine the link between genetics and memory problems in Parkinson's disease patients. Barrett hopes the research will eventually lead to customized treatments for Parkinson's disease patients.

30 Aug 2013

Blood test provides tool essential to trials of therapies for Huntington's disease

An assay designed to measure normal and abnormal forms of the huntingtin protein - the mutated form of which causes Huntington's disease - was successful in detecting levels of the mutant protein in a large multicenter study of individuals at risk for the devastating neurological disorder.

30 Aug 2013

Five things every person should know about Parkinson's disease

Michael J. Fox is back in the spotlight this fall in a new sitcom "The Michael J. Fox Show" and spreading awareness about Parkinson's disease, a condition both he and his TV character have in common. Fox has been an outspoken advocate for Parkinson's disease research and awareness since disclosing his condition to the public in 1998.

30 Aug 2013

GW researcher to receive $1.3M NIDDK grant to study how type 2 diabetes develops

A George Washington University researcher will receive $1.3 million over the next five years from the National Institute of Diabetes and Digestive and Kidney Diseases for research that will help better understand how type 2 diabetes develops, possibly informing the development of novel treatments to reverse the disease.

30 Aug 2013

Study: Overweight perception is independent predictor for suicidal ideation

Seeing oneself as overweight or obese may be an important, independent predictor of suicidal thoughts, especially in young girls, reports a new study in the Journal of Adolescent Health.

30 Aug 2013

Absence or presence of single protein can make cancer cells more or less susceptible to drugs

A new weakness has been discovered in cancer cells that may make them more susceptible to chemotherapy and other treatments. In a research report appearing in the September 2013 issue of The FASEB Journal, scientists identify the HDAC5 protein as being essential for the maintenance of structures, called telomeres, within cancer cells that promote cancer cells longevity.

30 Aug 2013

Dezima starts DEZ-001 Phase 2b study in patients with mild dyslipidemia

Dezima Pharma, the biotechnology company developing innovative drugs in the field of dyslipidemia, announced today the initiation of a double blind, placebo controlled, Phase 2b dose ranging study of DEZ-001 (previously TA-8995), alone and in combination with statins, in order to study the effects on a wide range of lipids and other biomarkers of cardiovascular disease in patients with mild dyslipidemia.

30 Aug 2013

Potential drug target to treat depression and other mood disorders may lie in GABA neurons

A new drug target to treat depression and other mood disorders may lie in a group of GABA neurons (gamma-aminobutyric acid -the neurotransmitters which inhibit other cells) shown to contribute to symptoms like social withdrawal and increased anxiety, Penn Medicine researchers report in a new study in the Journal of Neuroscience.

30 Aug 2013

Study reveals zinc-regulated small compound in blood mediates harmful effects of zinc deprivation

According to new research published in The FASEB Journal, a drop in blood zinc levels does not directly harm the blood vessel cells. Rather, zinc regulates the production of a small molecular compound, which then circulates in the blood and causes harmful blood vessel cell effects.

30 Aug 2013

Urinary protein may be early warning sign regarding patients' cognitive abilities

The presence of protein in the urine may be a marker of risk for future cognitive decline in patients with type 2 diabetes and normal kidney function, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

30 Aug 2013

Socioeconomic status more important barrier to living kidney donation than cultural factors

Socioeconomic status is a more important barrier to living kidney donation than cultural factors, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings may be useful for determining ways to increase living kidney donation in the United States.

30 Aug 2013

Study finds low adiponectin levels prior to pregnancy linked to high risk of gestational diabetes

Overweight women with low levels of the hormone adiponectin prior to pregnancy are nearly seven times more likely to develop gestational diabetes, according to a Kaiser Permanente study published today in the journal Diabetes Care. Adiponectin protects against insulin resistance, inflammation and heart disease.

30 Aug 2013

Researchers discover protein that may help predict breast cancer prognosis

Researchers have identified a protein that they believe may help predict breast cancer prognosis, potentially relieving thousands of women at low risk from having to undergo painful, oft-debilitating therapies, while insuring the most successful treatments for those at high risk. The research was published ahead of print in the journal Molecular and Cellular Biology.

30 Aug 2013

Engaging in physical activity not going to put at greater risk of knee osteoarthritis

Adults age 45 and older who engaged in moderate physical activity up to two and a half hours a week did not increase their risk of developing knee osteoarthritis over a 6-year follow-up period, a new study finds.

29 Aug 2013

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

A new clinical study at the University of Michigan Health System will test the ability of a once daily dose of doxycycline to reduce the growth of small abdominal aortic aneurysms.

29 Aug 2013

Mallinckrodt to present MNK-795 clinical data at PAINWeek 2013

Mallinckrodt announced today that the first clinical data on MNK-795 will be presented at PAINWeek 2013, to be held September 4-7 in Las Vegas. MNK-795 is an extended-release oral formulation of oxycodone and acetaminophen that has been studied in clinical trials for the management of moderate to severe acute pain where the use of an opioid analgesic is appropriate.

29 Aug 2013

Medical Condition News

Researchers identify mutation in CNGB1 gene causing PRA in Phalene and Papillon

BP and headache drug effectively speeds up treatment of TB

Scientists unravel how DNA damage may trigger lupus erythematosus

Diabetic patients could benefit from breakthrough cell study

Research team examines link between genetics and memory problems in Parkinson's patients

Blood test provides tool essential to trials of therapies for Huntington's disease

Five things every person should know about Parkinson's disease

GW researcher to receive $1.3M NIDDK grant to study how type 2 diabetes develops

Study: Overweight perception is independent predictor for suicidal ideation

Absence or presence of single protein can make cancer cells more or less susceptible to drugs

Dezima starts DEZ-001 Phase 2b study in patients with mild dyslipidemia

Potential drug target to treat depression and other mood disorders may lie in GABA neurons

Study reveals zinc-regulated small compound in blood mediates harmful effects of zinc deprivation

Urinary protein may be early warning sign regarding patients' cognitive abilities

Socioeconomic status more important barrier to living kidney donation than cultural factors

Study finds low adiponectin levels prior to pregnancy linked to high risk of gestational diabetes

Researchers discover protein that may help predict breast cancer prognosis

Engaging in physical activity not going to put at greater risk of knee osteoarthritis

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

Mallinckrodt to present MNK-795 clinical data at PAINWeek 2013

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