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Recycling protein molecules could lead to new therapies for Alzheimer's disease

The formation of abnormal strands of protein called amyloid fibrils - associated with two dozen diseases ranging from Alzheimer's to type-2 diabetes - may not be permanent and irreversible as previously thought, scientists are reporting in the Journal of the American Chemical Society.

26 May 2011

Tofacitinib safe and effective for patients with rheumatoid arthritis

Results of a Phase III study presented today at the EULAR 2011 Annual Congress show that at 6 months, 58.3 percent of patients who had previously not responded to treatment with DMARDs, achieved ACR20 response when treated with the novel oral Janus kinase inhibitor tofacitinib at 10mg BID compared to 31.2 percent in the placebo group. Significant improvements were also observed in the 5 mg BID dose.

26 May 2011

New insight into how genes and proteins go awry in autism to alter the mind

For decades, autism researchers have faced a baffling riddle: how to unravel a disorder that leaves no known physical trace as it develops in the brain.

26 May 2011

Precision ophthalmic tint lenses reduce migraine, study shows

Precision tinted lenses have been used widely to reduce visual perceptual distortions in poor readers, and are increasingly used for migraine sufferers, but until now the science behind these effects has been unclear.

26 May 2011

Emotional factors and mental health problems trigger alcohol-related offences in women

Female drink-drivers are more likely to be older, better-educated and divorced, widowed or separated, research has shown.

26 May 2011

Comprehensive insight into current neural stem cell research and therapies

A new article published by Cell Press in the May 26 issue of the journal Neuron provides comprehensive insight into the current status of neural stem cell research and the sometimes labyrinthine pathways leading to stem cell-based therapies.

26 May 2011

Low vitamin D could account for link between obesity and cancer, heart disease, diabetes

Overweight or obese women with less-than-optimal levels of vitamin D who lose more than 15 percent of their body weight experience significant increases in circulating levels of this fat-soluble nutrient, according to a new study by researchers at Fred Hutchinson Cancer Research Center.

26 May 2011

U.S. District Court grants temporary restraining order in Amylin's litigation against Lilly

Amylin Pharmaceuticals, Inc. today announced that the United States District Court for the Southern District of California issued a temporary restraining order (TRO) against Eli Lilly and Company relating to its litigation with respect to the Amylin / Lilly diabetes collaboration agreement.

26 May 2011

Ardea reports additional results from lesinurad-allopurinol Phase 2b study in hyperuricemia, gout

Ardea Biosciences, Inc. announced that additional positive clinical and preclinical results from its development program of lesinurad, the Company's lead product candidate for the treatment of hyperuricemia and gout, were presented at the Annual European Congress of Rheumatology hosted by the European League Against Rheumatism in London, UK.

26 May 2011

Novel way to immobilise radioactive iodine

A novel way to immobilise radioactive forms of iodine using a microwave, has been discovered by an expert at the University of Sheffield.

26 May 2011

Paxil and Pravachol in combination cause unexpected increase in blood glucose levels

A widely used combination of two common medications may cause unexpected increases in blood glucose levels, according to a study conducted at the Stanford University School of Medicine, Vanderbilt University and Harvard Medical School. Researchers were surprised at the finding because neither of the two drugs - one, an antidepressant marketed as Paxil, and the other, a cholesterol-lowering medication called Pravachol - has a similar effect alone.

26 May 2011

The Rockefeller University to honor pioneering memory researcher with Pearl Meister Greengard Prize

Brenda Milner, Ph.D., a pioneer in the field of cognitive neuroscience whose discoveries revolutionized the understanding of memory, will be awarded the 2011 Pearl Meister Greengard Prize from The Rockefeller University.

26 May 2011

Study: Protein drinks after aerobic activity help older people build more formidable muscles

A new research report appearing online in the FASEB Journal shows that what someone drinks after exercise plays a critical role in maximizing the effects of exercise.

26 May 2011

Non-invasive trigeminal nerve stimulation shows promise in controlling seizures

Medications are the mainstay of treatment for epilepsy, but for a considerable number of patients - estimated to be as many as 1 million in the U.S. - drugs don't work. These patients suffer from a type of epilepsy known as refractory or drug-resistant epilepsy, in which drugs can't control their seizures.

26 May 2011

Study to examine whether red wine component could help reduce concussions in pro boxers

UT Southwestern Medical Center researchers are engaging the help of professional boxers and trainers to study whether a component in red wine and grapes could help reduce the short- and long-term effects of concussions.

26 May 2011

NIH-funded analysis finds 19% of young adults with high blood pressure

Roughly 19 percent of young adults may have high blood pressure, according to an analysis of the National Longitudinal Study of Adolescent Health, which is supported by the National Institutes of Health.

26 May 2011

There's no upper age limit for balloon angioplasties

Loyola University Health System interventional cardiologist Dr. Ferdinand Leya says there's no upper age limit for performing balloon angioplasties.

26 May 2011

Metyrapone reduces brain's ability to re-record negative emotions associated with recalling painful memories

Recalling painful memories while under the influence of the drug metyrapone reduces the brain's ability to re-record the negative emotions associated with them, according to University of Montreal researchers at the Centre for Studies on Human Stress of Louis-H. Lafontaine Hospital.

26 May 2011

Scientists discover new mechanism that controls inflammation

The molecular machines that defend our body against infection don't huff and puff, but some of them apparently operate on the same principle as a steam engine.

26 May 2011

GE Healthcare receives FDA 510k clearance for CoreScan to treat obesity-related disease

GE Healthcare today announced 510k clearance of CoreScan - a widely-accessible application dedicated to quickly and accurately quantifying visceral adipose tissue, or visceral "belly" fat, during body composition analysis.

26 May 2011

Medical Condition News

Recycling protein molecules could lead to new therapies for Alzheimer's disease

Tofacitinib safe and effective for patients with rheumatoid arthritis

New insight into how genes and proteins go awry in autism to alter the mind

Precision ophthalmic tint lenses reduce migraine, study shows

Emotional factors and mental health problems trigger alcohol-related offences in women

Comprehensive insight into current neural stem cell research and therapies

Low vitamin D could account for link between obesity and cancer, heart disease, diabetes

U.S. District Court grants temporary restraining order in Amylin's litigation against Lilly

Ardea reports additional results from lesinurad-allopurinol Phase 2b study in hyperuricemia, gout

Novel way to immobilise radioactive iodine

Paxil and Pravachol in combination cause unexpected increase in blood glucose levels

The Rockefeller University to honor pioneering memory researcher with Pearl Meister Greengard Prize

Study: Protein drinks after aerobic activity help older people build more formidable muscles

Non-invasive trigeminal nerve stimulation shows promise in controlling seizures

Study to examine whether red wine component could help reduce concussions in pro boxers

NIH-funded analysis finds 19% of young adults with high blood pressure

There's no upper age limit for balloon angioplasties

Metyrapone reduces brain's ability to re-record negative emotions associated with recalling painful memories

Scientists discover new mechanism that controls inflammation

GE Healthcare receives FDA 510k clearance for CoreScan to treat obesity-related disease

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