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Working Group recommends use of biomarkers in AD clinical trials

A group of thought leaders in Alzheimer's disease says the science is solid and the time has come for more widespread use of biomarkers in Alzheimer disease (AD) clinical trials, to speed the identification of effective disease-modifying treatments for this incurable disorder.

5 Jan 2012

Re-introduction of rotavirus vaccine does not increase intussusception rates in the U.S.

The rotovirus vaccine was pulled from the marketplace in 1999 after being associated with painful gastrointestinal complications, however, the updated rotavirus vaccines do not appear to increase the occurrence of these potentially fatal side effects, according to a new study by child health experts at C.S. Mott Children's Hospital.

5 Jan 2012

BMI method can determine expected body weight for adolescents with eating disorders

An exact determination of expected body weight for adolescents based on age, height and gender is critical for diagnosis and management of eating disorders such as anorexia nervosa and bulimia. However, there are no clear guidelines regarding the appropriate method for calculating this weight in children with such disorders.

5 Jan 2012

ACS report shows decline in overall cancer death rates

The American Cancer Society's annual cancer statistics report shows that between 2004 and 2008, overall cancer incidence rates declined by 0.6% per year in men and were stable in women, while cancer death rates decreased by 1.8% per year in men and by 1.6% per year in women.

5 Jan 2012

Itamar, Roche to further develop EndoPAT technology for pre-clinical trials

Itamar-Medical, the world's leader of non-invasive devices for diagnosis of cardiovascular health, announced achievement of the next milestone of the international pharmaceutical company, Roche, to further develop the EndoPAT technology for pre-clinical trials.

5 Jan 2012

Hypothermia rarely used in the U.S. hospitals to reduce heart attack cases

Therapeutic hypothermia has been proven to reduce mortality and improve neurologic outcomes after a heart attack, yet it was rarely used in a sample of more than 26,000 patients, according to a study published in Therapeutic Hypothermia and Temperature Management, a peer-reviewed journal published by Mary Ann Liebert, Inc.

5 Jan 2012

JHTR, COMBI introduce 'Tools for Clinical Use'

Starting this month, The Journal of Head Trauma Rehabilitation (JHTR)—in partnership with The Center For Outcome Measurement in Brain Injury (COMBI)—introduces a new feature designed to support effective and informed use of standardized assessments for evaluation of brain injury.

5 Jan 2012

New brochure makes planning and monitoring post-cancer exercise easy

Not only is overall quality of life higher in cancer survivors who exercise, but the rate of cancer recurrence is lower. Unfortunately, though most doctors recommend exercise, many patients fail to follow through.

5 Jan 2012

Celldex begins rindopepimut and Avastin Phase 2 combination trial in EGFRvIII-positive GB

Celldex Therapeutics, Inc. today announced that patient screening has initiated in a Phase 2 trial of rindopepimut in combination with Avastin in patients with recurrent epidermal growth factor variant III (EGFRvIII)-positive glioblastoma, called the "ReACT Study."

5 Jan 2012

UCSD scientist honored for Down syndrome research

William C. Mobley, MD, PhD, chair of the Department of Neurosciences at the University of California, San Diego School of Medicine and Chairman of the U.S. Scientific Advisory Committee of the J-r-me Lejeune Foundation, was recognized by U.S. Congressman Pete Sessions from the floor of the House of Representatives in December. Sessions said of Mobley - who received the International Sisley-J-r-me Lejeune Prize in a ceremony at the Museum of Medical History in Paris on December 8.

5 Jan 2012

Bionomics, Ironwood partner to develop and commercialize novel anti-anxiety compound

Ironwood Pharmaceuticals, Inc. and Bionomics Limited today announced that they entered into a collaboration, research, and licensing agreement that will enable Ironwood to develop and commercialize Bionomics' investigational anti-anxiety compound BNC210 and other related compounds.

5 Jan 2012

RGS9-2 gene plays a role in regulating body weight

Abraham Kovoor was studying a brain protein, called RGS9 2, that he had previously related to the involuntary, random and repetitive body movements that are side effects of drugs used to treat Parkinson's disease and schizophrenia.

5 Jan 2012

Antiestrogen supplements may reduce risk of melanoma in women with breast cancer

Women with breast cancer who take antiestrogen supplements may be decreasing their risk for melanoma, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

5 Jan 2012

Positive results from Alkermes ALKS 5461 phase 1/2 study on MDD

Alkermes plc today announced positive topline results from a phase 1/2 study of ALKS 5461, a novel drug compound for major depressive disorder (MDD) in patients who have an inadequate response to standard therapies for clinical depression.

5 Jan 2012

First study to elucidate how statins reduce activation of abnormal blood clotting

People with high cholesterol are at risk of heart attack and stroke because atherosclerotic plaques within their arteries can rupture triggering the formation of a blood clot called an occlusive thrombus that cuts off the blood supply to their heart or brain.

5 Jan 2012

IHoP may play a critical role in type 1 diabetes

Researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine and colleagues have discovered a new protein that may play a critical role in how the human body regulates blood sugar levels.

5 Jan 2012

Free public lecture to look at role of stents in treating coronary artery diseases

State-of-the art treatments for patients with heart problems are the theme of a public lecture at the University of Greenwich this month. The lecture, which is free and open to all, will look at the role of stents in treating coronary artery diseases. A stent is a tiny, artificial tube which is placed in the coronary arteries that supply the heart: by keeping the arteries open, the stent combats the effects of reduced blood flow, such as blood clots.

5 Jan 2012

Lithocholic acid can kill several types of cancer cells

Lithocholic acid (LCA), naturally produced in the liver during digestion, has been seriously underestimated. A study published in the journal Oncotarget shows that LCA can kill several types of cancer cells, such as those found in some brain tumors and breast cancer.

5 Jan 2012

Positive preliminary results from Alnylam's Phase I ALN-PCS trial on severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today the achievement of positive preliminary results from its ongoing clinical trial of ALN-PCS, an RNAi therapeutic targeting PCSK9 for the treatment of severe hypercholesterolemia.

5 Jan 2012

NGP receives investment from Abbott to develop NGP 555 for AD

NeuroGenetic Pharmaceuticals, Inc. (NGP), a privately held biopharmaceutical company focused on Alzheimer's disease (AD) therapeutics, has received an investment from Abbott Biotech Ventures.

5 Jan 2012

Medical Condition News

Working Group recommends use of biomarkers in AD clinical trials

Re-introduction of rotavirus vaccine does not increase intussusception rates in the U.S.

BMI method can determine expected body weight for adolescents with eating disorders

ACS report shows decline in overall cancer death rates

Itamar, Roche to further develop EndoPAT technology for pre-clinical trials

Hypothermia rarely used in the U.S. hospitals to reduce heart attack cases

JHTR, COMBI introduce 'Tools for Clinical Use'

New brochure makes planning and monitoring post-cancer exercise easy

Celldex begins rindopepimut and Avastin Phase 2 combination trial in EGFRvIII-positive GB

UCSD scientist honored for Down syndrome research

Bionomics, Ironwood partner to develop and commercialize novel anti-anxiety compound

RGS9-2 gene plays a role in regulating body weight

Antiestrogen supplements may reduce risk of melanoma in women with breast cancer

Positive results from Alkermes ALKS 5461 phase 1/2 study on MDD

First study to elucidate how statins reduce activation of abnormal blood clotting

IHoP may play a critical role in type 1 diabetes

Free public lecture to look at role of stents in treating coronary artery diseases

Lithocholic acid can kill several types of cancer cells

Positive preliminary results from Alnylam's Phase I ALN-PCS trial on severe hypercholesterolemia

NGP receives investment from Abbott to develop NGP 555 for AD

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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