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BU scientists create unique material and drug delivery mechanism

Long duration, controllable drug delivery is of wide interest to medical researchers and clinicians, particularly those seeking to improve treatment for patients with chronic pain or to prevent cancer recurrence after surgery. Now a team of researchers led by Boston University Biomedical Engineer and Chemist Mark Grinstaff has developed a unique material and drug delivery mechanism that could pave the way for implants that release a drug at a designated rate for months.

1 Feb 2012

New ultrasound can overcome challenges linked with kidney stone treatment

Just the mention of kidney stones can cause a person to cringe. They are often painful and sometimes difficult to remove, and 10 percent of the population will suffer from them. In space, the risk of developing kidney stones is exacerbated due to environmental conditions. The health risk is compounded by the fact that resource limitations and distance from Earth could restrict treatment options.

1 Feb 2012

Researchers use liquid laser to diagnose genetic mutations linked with cancer

Using a liquid laser, University of Michigan researchers have developed a better way to detect the slight genetic mutations that might predispose a person to a particular type of cancer or other diseases.

1 Feb 2012

OPN-305 may improve survival outcomes for kidney transplant patients

New research published online in the FASEB Journal details a new antibody, called "OPN-305" that may significantly improve survival outcomes for those receiving donated kidneys and other organs.

1 Feb 2012

Progenitor cells have potential to develop into RBCs

A study of the cells that respond to crises in the blood system has yielded a few surprises, redrawing the 'map' of how blood cells are made in the body.

1 Feb 2012

Initial data from Abiomed's Symphony safety trial on chronic heart failure

Abiomed Inc., a leading provider of breakthrough heart support technologies, today announced that the initial clinical data from the safety study for Symphony was presented by Renzo Cecere, M.D., FRCSC, FACS, Associate Professor of Surgery at McGill University, during the late-breaking clinical trials session at the Society of Thoracic Surgeons (STS) 2012 Annual Meeting in Fort Lauderdale, Florida.

1 Feb 2012

RMC first in N.J. to offer TESSYS minimally invasive surgery for patients with herniated discs

Riverview Medical Center, part of Meridian Neuroscience, today announced it is the only hospital in the state of New Jersey to offer patients the TESSYS surgery method, a minimally invasive procedure for the treatment of herniated discs.

1 Feb 2012

General anesthesia may lower recurrence risk in patients with HCC

For patients undergoing a minimally invasive treatment for liver cancer, the risk of recurrent cancer appears lower with general anesthesia compared to regional (epidural) anesthesia, reports a study in the February issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

1 Feb 2012

TGen, UA receive NFCR grant to study targeted pancreatic cancer therapies

The Translational Genomics Research Institute (TGen) and the University of Arizona (UA) have received a three-year, $600,000 grant to study targeted cancer therapies from the National Foundation for Cancer Research.

1 Feb 2012

Early retirement due to back problems reduces long-term financial capacity

Back problems are a highly prevalent health issue, and people with the condition have a significantly greater chance of retiring early from the workforce, much more so than for any other health condition. A group of Australian researchers reports that not only does early retirement limit the immediate income available to these individuals, but it also reduces their long-term financial capacity, by reducing their ability to accumulate wealth to a significant degree.

1 Feb 2012

Preliminary results from CINJ's Celebrex and Lipitor Phase II combination trial on prostrate cancer

Research from The Cancer Institute of New Jersey (CINJ) on the FDA-approved drugs Celebrex and Lipitor -- used respectively for arthritis pain and lowering cholesterol -- shows that these drugs are well tolerated in the treatment of recurrent prostate cancer.

1 Feb 2012

Certain strains of P. aeruginosa cause WBCs to produce high levels of histamine

Could some cases of asthma actually be caused by an allergic reaction to a common environmental bacteria? New research findings published in the Journal of Leukocyte Biology suggests that this idea may not be as far-fetched as it seems. In a research report appearing in the February 2012 print issue, researchers show a link between common environmental bacteria and airway inflammation.

1 Feb 2012

Dana-Farber receives MLSC grant to expand cancer imaging research

The Massachusetts Life Sciences Center has awarded Dana-Farber Cancer Institute a $10 million grant to support the expansion of its pioneering cancer imaging research program.

1 Feb 2012

Specific gene mutation triggers development of NAFLD

A team of scientists from the University of Utah and the University of California at San Francisco has discovered that the mutation of a gene encoding a ketone body transporter triggers accumulation of fat and other lipids in the livers of zebrafish.

1 Feb 2012

Study finds sharp increase in BMP use for spinal fusion surgery

The use of bone morphogenetic protein (BMP) for spinal fusion surgery has risen sharply over the past decade, increasing costs with no evidence of improved outcomes, reports study in the February 1 issue of Spine.

1 Feb 2012

Novartis' Gleevec receives FDA approval for use in patients with CD117-positive GIST

The U.S. Food and Drug Administration today granted Gleevec (imatinib) regular approval for use in adult patients following surgical removal of CD117-positive gastrointestinal stromal tumors.

1 Feb 2012

Study finds no link between BDV and psychiatric illness

Over the past 30 years, numerous studies have linked Borna disease virus (BDV) with mental illnesses such as bipolar disorder, schizophrenia, anxiety disorder and dementia. Genetic fragments and antibodies to this RNA virus, which causes behavior disorders in a range of mammals and birds, have been found to be prevalent in psychiatric patients, but study results have been inconsistent. Now, the first blinded, case-control study to examine this issue finds no association between the virus and psychiatric illness.

1 Feb 2012

Adults with profound learning disability more likely to develop autism

New research on autism in adults has shown that adults with a more severe learning disability have a greater likelihood of having autism.

1 Feb 2012

Rensselaer professor wins CAREER Award from NSF

Ryan Gilbert, assistant professor in the Department of Biomedical Engineering at Rensselaer Polytechnic Institute, has won a prestigious Faculty Early Career Development Award (CAREER) from the National Science Foundation (NSF).

1 Feb 2012

Crizotinib can treat ROS1-driven tumors

A report from investigators at the Massachusetts General Hospital (MGH) Cancer Center has defined the role of a recently identified gene abnormality in a deadly form of lung cancer. Tumors driven by rearrangements in the ROS1 gene represent 1 to 2 percent of non-small-cell lung cancers (NSCLC), the leading cause of cancer death in the U.S.

1 Feb 2012