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ORMOSIL nanoparticles show promise as potential drug delivery vehicle

In the images of fruit flies, clusters of neurons are all lit up, forming a brightly glowing network of highways within the brain. It's exactly what University at Buffalo researcher Shermali Gunawardena was hoping to see: It meant that ORMOSIL, a novel class of nanoparticles, had successfully penetrated the insects' brains. And even after long-term exposure, the cells and the flies themselves remained unharmed.

10 Jan 2012

Young female cancer survivors concerned about their future fertility

Young female cancer survivors are concerned about their future fertility and parenthood options and want better information and guidance early on, according to a new study by Jessica Gorman and her team from the University of California in the US.

10 Jan 2012

Delaying hypertension treatment in diabetic patients for up to a year is unlikely to be harmful

Confronted with a high blood pressure value in a diabetic patient, most doctors would treat aggressively with medications. According to new research, however, delaying drug treatment for up to a year is unlikely to be harmful. The delay allows doctors and their patients to focus on lifestyle changes such as salt restriction, weight management, and exercise.

10 Jan 2012

New evidence on heading and risk of brain injury in soccer

Could heading the ball in soccer lead to degenerative brain disease, like that seen in athletes in other sports? That's the question addressed by a review in the January issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

10 Jan 2012

Cardiologist measures risk factors associated with CR

The cardiologist Aitor Jim-nez has managed to gather and characterise in detail 110 cases of cardiac rupture (CR), after spending 22 years (1978-2000) gathering data at the Hospital de Cruces, near Bilbao. It is one of the broadest anatomical series described in this respect. CR is the most serious complication of acute myocardial infarction; it is not very common, but when it does occur, it is mortal in practically all cases. So prevention, although difficult, seems more feasible than cure.

10 Jan 2012

'Where is my Memory? Cognitive Changes in MS' teleconference to be held on Jan. 24

John DeLuca, PhD, VP for Research at Kessler Foundation, will conduct a teleconference, "Where is my Memory? Cognitive Changes in MS," on Tues., January 24, 6:30-7:30 pm. Dr. DeLuca is well known for his neuropsychology research in cognition and multiple sclerosis and is a licensed psychologist in New Jersey and New York.

10 Jan 2012

Nicotine patch may help improve mild memory loss in older adults

Using a nicotine patch may help improve mild memory loss in older adults, according to a study published in the January 10, 2012, print issue of Neurology, the medical journal of the American Academy of Neurology.

10 Jan 2012

Study confirms safety and effectiveness of rAHF-PFM in managing hemophilia A

A Rush University Medical Center led international research team has announced that a treatment to prevent bleeding episodes in children with hemophilia A also is effective for adolescents and adults.

10 Jan 2012

Study demonstrates that individuals can eat out and still lose weight

Going out to eat has become a major part of our culture. Frequently eating out and consuming high-calorie foods in large portions at restaurants can contribute to excess calorie intake and weight gain. However, a study in the January/February 2012 issue of the Journal of Nutrition Education and Behavior demonstrates that individuals can eat out and still lose weight.

10 Jan 2012

MAL3-101 appears to have potent anti-tumor effects on multiple myeloma

A new study from SUNY Downstate Medical Center in Brooklyn, New York, shows that MAL3-101, a recently developed inhibitor of the heat shock protein 70 (Hsp70), appears to have potent anti-tumor effects on multiple myeloma, a bone marrow cancer.

10 Jan 2012

QIAGEN's therascreen EGFR Mutation Detection Kit receives Japanese regulatory approval

QIAGEN today announced the regulatory approval of its therascreen EGFR Mutation Detection Kit RGQ in Japan. EGFR, the epidermal growth factor receptor, has been shown to play an important role in certain cancers and is the target of many new anticancer drugs.

From QIAGEN Manchester Limited 10 Jan 2012

Experts want young athletes to become more aware of warning signs of concussion

Concussion in youth sports is a serious issue, as young athletes' brains are more susceptible to injuries. These injuries can become more serious as players suffer repeated incidents. Sports related concussions have generated a significant amount of attention, with numerous well-known school and professional athletes out of the game due to concussion.

10 Jan 2012

Researchers create prostate cancer drug delivery system

Honing chemotherapy delivery to cancer cells is a challenge for many researchers. Getting the cancer cells to take the chemotherapy "bait" is a greater challenge. But perhaps such a challenge has not been met with greater success than by the nanotechnology research team of Omid Farokhzad, MD, Brigham and Women's Hospital (BWH) Department of Anesthesiology Perioperative and Pain Medicine and Research.

10 Jan 2012

Scientists analyze effect of nationwide tax on sweetened beverages

Every year, Americans drink 13.8 billion gallons of soda, fruit punch, sweet tea, sports drinks, and other sweetened beverages—a mass consumption of sugar that is fueling soaring obesity and diabetes rates in the United States. Now a group of scientists at the University of California, San Francisco (UCSF), San Francisco General Hospital and Trauma Center (SFGH) and Columbia University have analyzed the effect of a nationwide tax on these sugary drinks.

10 Jan 2012

Urinary biomarkers can diagnose AKI in high-risk patients

Acute kidney injury (AKI) has severe consequences, with a 25 to 80 percent risk of in-hospital death. Researchers have found a way to diagnose AKI using a urine test, enabling emergency departments to identify these high-risk patients when they first arrive at the hospital.

10 Jan 2012

Personalized therapies may improve survival and QoL of patients with glioblastoma

Personalized prognostic tools and gene-based therapies may improve the survival and quality of life of patients suffering from glioblastoma, an aggressive and deadly form of brain cancer, reports a new University of Illinois study funded by the NIH National Cancer Institute.

10 Jan 2012

Insulin induces formation of new elastin in cultures of human aortic smooth muscle cells

New research reveals that insulin applied in therapeutic doses selectively stimulates the formation of new elastic fibers in cultures of human aortic smooth muscle cells.

10 Jan 2012

Amylin outlines key strategic priorities for 2012

Amylin Pharmaceuticals, Inc. today outlined its key strategic priorities for 2012, with a strong focus on driving the global commercial value of its diabetes franchise.

10 Jan 2012

Nicotine patch may boost memory in individuals with MCI

Wearing a nicotine patch may help improve memory loss in older adults with mild cognitive impairment, according to a study published today in Neurology, the medical journal of the American Academy of Neurology.

10 Jan 2012

Researchers uncover exact function of LARGE enzyme linked with MD

Researchers at the University of Iowa have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings, which were published Jan. 6 in the journal Science,, could be used to develop rapid, large-scale testing of potential muscular dystrophy therapies.

10 Jan 2012