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Researchers question wisdom of blocking DP1 in patients prone to cardiovascular disease

Niacin, or vitamin B3, is the one approved drug that elevates "good" cholesterol (high density lipoprotein, HDL) while depressing "bad" cholesterol (low density lipoprotein , LDL), and has thereby attracted much attention from patients and physicians. Niacin keeps fat from breaking down, and so obstructs the availability of LDL building blocks.

9 Apr 2012

Heart cells starved of nutrients less likely to be damaged during ischemia, reperfusion

Heart cells starved of nutrients are less likely to be damaged during periods of decreased blood flow and sudden influxes of blood, known as ischemia and reperfusion, and are also less likely to get out of synch with their cellular neighbors, the damaging phenomenon called arrhythmia.

9 Apr 2012

Nuron Biotech licenses DNA amyloid beta 42 vaccine for AD

Nuron Biotech, Inc. today announced it has licensed from VITRUVIAN BioMedical, Inc. a gene-based (DNA) amyloid beta 42 (Aβ42) vaccine in preclinical development for Alzheimer's disease (AD).

9 Apr 2012

NINDS awards NeuroSigma Phase I grant to develop TFN-covered stents

NeuroSigma, Inc., a Los Angeles-based medical device company, today announced it has been awarded a Phase I NIH-STTR grant from the National Institute of Neurological Disorders and Stroke (NINDS) for the further development of its Thin-Film Nitinol (TFN)-covered stent for the potential treatment of brain aneurysms.

9 Apr 2012

Inflammasome involved in regulating Age-Related Macular Degeneration

Scientists at Trinity College Dublin have discovered that a part of the immune system called the inflammasome is involved in regulating the development of one of the most common forms of blindness, called Age-Related Macular Degeneration.

9 Apr 2012

Researchers discover two molecules that control liver glucose production

In their extraordinary quest to decode human metabolism, researchers at the Salk Institute for Biological Studies have discovered a pair of molecules that regulates the liver's production of glucose---- the simple sugar that is the source of energy in human cells and the central player in diabetes.

9 Apr 2012

Scientists discover novel genes that are mutated in stomach cancer

An international team of scientists, led by researchers from the Duke-NUS Graduate Medical School (Duke-NUS) in Singapore and National Cancer Centre of Singapore, has identified hundreds of novel genes that are mutated in stomach cancer, the second-most lethal cancer worldwide.

9 Apr 2012

CPF proclaims September as 'Pulmonary Fibrosis Awareness Month'

The Coalition for Pulmonary Fibrosis (CPF) announced today the month of September 2012 will be proclaimed "Pulmonary Fibrosis Awareness Month." In previous years, the CPF has celebrated "National Pulmonary Fibrosis Awareness Week" for one week each September, but expanding the time frame to a month will help achieve greater national awareness and fundraising in the race to find treatment and a cure.

7 Apr 2012

Free brain health screenings at Sam's Club

Everyone forgets sometimes. A certain degree of memory problems are a common part of aging. There is a difference, however, between changes in memory and memory loss from Alzheimer's disease. One in eight adults over the age of 65 is diagnosed with Alzheimer's, and 20 percent of the elderly population suffers from some form of dementia. If detected early, some memory loss can be manageable by taking simple steps to improve brain function.

7 Apr 2012

Bikers raise funds for The Gateway For Cancer Research

Live, Love and Ride…that's the slogan on BikerMonkey's blog post. If only life was truly that simple. Cancer affects virtually every family in some way… loved ones, friends, neighbors and coworkers.

7 Apr 2012

'Benefits and burdens' of participating in clinical research trials

In one of the first studies of its kind, University of Pennsylvania School of Nursing researchers have identified what cancer patients consider the "benefits and burdens" of participating in clinical research trials.

7 Apr 2012

Two Rev-erb proteins work together to control fat metabolism

The 24-hour internal clock controls many aspects of human behavior and physiology, including sleep, blood pressure, and metabolism. Disruption in circadian rhythms leads to increased incidence of many diseases, including metabolic disease and cancer. Each cell of the body has its own internal timing mechanism, which is controlled by proteins that keep one another in check.

7 Apr 2012

G8 should discuss world's over-60 population to develop policies for 'healthy, active and productive aging'

"Within five years, for the first time in history, the number of adults 65 and older will exceed the number of children younger than five, the World Health Organization reports," "which is why the aging global population's impact on social stability, economic growth and fiscal sustainability should be part of the agenda at next month's Group of Eight summit," Michael Hodin, an adjunct senior fellow at the Council on Foreign Relations and executive director of the Global Coalition on Aging, writes in a Washington Post opinion piece.

7 Apr 2012

NORD, Corcept partner to establish Cushing's Syndrome Patient Assistance Program

In partnership with Corcept Therapeutics Inc., the National Organization for Rare Disorders (NORD) has established a Cushing's Syndrome Patient Assistance Program for patients with endogenous Cushing's syndrome who need financial assistance with certain costs related to their medical diagnosis and/or care.

7 Apr 2012

Swedish Neuroscience Institute to open new MS Center

Swedish Neuroscience Institute (SNI) will open its new MS Center at Swedish to patients on April 9. Carefully designed for easy accessibility and to promote the well-being of people with Multiple Sclerosis (MS), the new 11,700-square-foot center gives SNI the ability to consolidate all of its MS services into one facility.

7 Apr 2012

Alternative therapy for knee surgery from The Pain Whisperer

Jeremy Lin is scheduled to undergo surgery for his knee within the week and will be down for six weeks, ending his season. Tom Chi, also known as The Pain Whisperer and star of the upcoming reality TV series of the same name, offers a remarkable alternative therapy to this type of surgery.

7 Apr 2012

Elevated pulse pressure may increase risk of CVD in older adults with AD

Researchers at the University of California, San Diego and Veterans Affairs San Diego Healthcare System have shown that elevated pulse pressure may increase the risk of cerebrovascular disease (CVD) in older adults with Alzheimer's disease.

7 Apr 2012

Left ventriculography being routinely performed during coronary angiogram

An invasive heart test used routinely to measure heart function is being dramatically overused, especially among patients who recently underwent similar, more effective tests, according to a new study from the Stanford University School of Medicine.

7 Apr 2012

C8 MediSensors seeks CE Mark Approval for Optical Glucose Monitor

C8 MediSensors, Inc., the leader in developing non-invasive continuous glucose monitoring for people with diabetes, announced today that it has filed for CE mark approval to market the C8 MediSensors Optical Glucose Monitor in Europe. The monitor is currently an adjunct investigational device.

7 Apr 2012

FDA grants IDE approval for Arteriocyte's Magellan MAR01 Phase I Compartment Syndrome clinical trial

Arteriocyte, a leading biotechnology company with offices in Cleveland, Ohio and Hopkinton, Massachusetts announced today approval from the Food and Drug Administration (FDA) to initiate a Phase I clinical trial using its Magellan MAR01 technology in the treatment of Compartment Syndrome.

7 Apr 2012