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Researchers discover how normal cells in tumors can drive cancer growth

•A new study published in the journal Nature Cell Biology has discovered how normal cells in tumors can fuel tumor growth.

22 Dec 2011

New pharma title from iSmithers ‘Update on Polymers for Ocular Drug Delivery’

The eye is the most easily accessible site for topical administration of a medication. Drugs are commonly applied to the eye for localised action on the surface or in the interior of the eye. A major problem in ocular therapeutics is the attainment of an optimal drug concentration at the site of action.

21 Dec 2011

Holiday diet tips for people with diabetes

Each year, the holiday season brings good tidings and cheer along with an abundance of sweet treats, from tasty eggnog to candy canes. The holiday food frenzy actually begins with Halloween candy and lingers all the way until the big game, offering a steady stream of tempting goodies that can be a real hazard for the millions of people living with diabetes or at risk for diabetes.

21 Dec 2011

Actavis enters LOI with QRxPharma to commercialize MoxDuo IR in the U.S.

Actavis Group, the international generic pharmaceuticals company, today announced that its US subsidiary, Actavis Inc, has entered into a binding letter of intent (LOI) with QRxPharma Limited to commercialize MoxDuo IR in the United States.

21 Dec 2011

Denali Concrete Management initiates enrollment in CF101 phase 3 study for Dry Eye Syndrome

Denali Concrete Management Inc. announced today that it has commenced patient enrollment for a phase 3 clinical study of the safety and efficacy of CF101, daily administered orally, in patients with moderate-to-severe Dry Eye Syndrome.

21 Dec 2011

Chlorthalidone may reduce risk of death in patients with systolic hypertension

Patients with systolic hypertension who were treated with the diuretic chlorthalidone for 4.5 years as part of a clinical trial had a significantly lower rate of death and a gain in life expectancy free from cardiovascular death about 20 years later compared to patients who received placebo, according to a study in the December 21 issue of JAMA.

21 Dec 2011

FDA, other organizations unveil program to monitor cataract surgery devices

The U.S. Food and Drug Administration and other government and professional organizations today unveiled a program to monitor medical devices used in cataract surgery in an effort to stem outbreaks of a rare, inflammatory condition associated with the procedure.

21 Dec 2011

Antihypertensive drug therapy associated with longer life expectancy

More than 68 percent of Americans 65 and older - 80 percent age 75 and over - have hypertension (high blood pressure), according to a 2010 report by the Centers for Disease Control. Left untreated, this chronic condition can lead to stroke, heart attack, heart failure or premature death. Researchers at UMDNJ-Robert Wood Johnson Medical School have shown in a follow-up to the landmark clinical trial, Systolic Hypertension in the Elderly Program (SHEP), that the use of antihypertensive drug therapy is associated with longer life expectancy.

21 Dec 2011

Surgeon volume and in-hospital mortality for open AAA repair

Researchers from Southwestern Texas University's Division of Vascular and Endovascular Surgery and the Veterans Medical Center, both in Dallas, have reported that composite surgeon (overall) volume rather than operation-specific (annual) surgeon volume is a key determinant of in-hospital mortality for elective open abdominal aortic aneurysm surgery.

21 Dec 2011

Researchers discover how spinning microparticles can direct neuron growth

Researchers at UC Irvine and The University of Texas at Arlington have discovered how spinning microparticles can direct the growth of nerve fiber, a discovery that could allow for directed growth of neuronal networks on a chip and improve methods for treating spinal or brain injuries.

21 Dec 2011

Researchers discover one of vitamin E's normal body functions

It's rubbed on the skin to reduce signs of aging and consumed by athletes to improve endurance but scientists now have the first evidence of one of vitamin E's normal body functions.

21 Dec 2011

New method uses cultured skin cells to detect contact allergy

Contact allergy affects around 20% of the population in the western world. Scientists are working intensively to develop alternative test methods that do not require animal testing. A research group at the University of Gothenburg, Sweden, has now developed a unique test method that enables graded results to be obtained using cultured skin cells.

21 Dec 2011

Despite improvements, disparities in diagnosis and treatment of depression remain

Despite improvements to diagnostic tools and therapies in the two last decades, significant disparities in the diagnosis and treatment of depression remain, according to Rutgers research published online by the American Journal of Public Health; print, February 2012.

21 Dec 2011

CSF biomarkers can help detect early stage of Alzheimer's

Analysis of the cerebrospinal fluid can detect whether a person has Alzheimer's disease before symptoms appear. Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have studied biomarkers that offer more reliable diagnosis and, in the longer term, the possibility of effective new treatments.

21 Dec 2011

GSK, ProteoTech enter R&D agreement to develop new Parkinson's therapeutics

ProteoTech, Inc., a privately held biotechnology company, has entered into a drug development agreement with GlaxoSmithKline (China) R&D Company Limited (GSK) to collaborate on ProteoTech's small molecule technology platform against misfolded proteins to specifically advance work on its alpha-synuclein therapeutic program for the treatment of Parkinson's disease and other synucleinopathies.

21 Dec 2011

Mother's milk for healthy growth

A PhD project from LIFE - the Faculty of Life Sciences at the University of Copenhagen has shown that breastfed children follow a different growth pattern than non-breastfed children. Breastfeeding lowers the levels of the growth hormones IGF-I and insulin in the blood, which means that growth is slightly slower. This is believed to reduce the risk of overweight and diabetes later in life.

21 Dec 2011

Study examines changes in RHR with risk of death from ischemic heart disease

In a study that enrolled nearly 30,000 apparently healthy men and women, those who had an increase in their resting heart rate over a 10-year period had an increased risk of death from all causes and from ischemic heart disease, according to a study in the December 21 issue of JAMA.

21 Dec 2011

Anxious individuals are less sensitive to their environments: Study

Anxious people have long been classified as "hypersensitive" - they're thought to be more fearful and feel threatened more easily than their counterparts. But new research from Tel Aviv University shows that the anxious may not be hypersensitive at all - in fact, they may not be sensitive enough.

21 Dec 2011

CWRU receives NIDDK grant to study role of innate immunity in IBD

Investigators at Case Western Reserve University School of Medicine received a $6.75 million Program Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to study the role of innate immunity in inflammatory bowel disease.

21 Dec 2011

Study assesses evidence of immunosuppression in sepsis

An analysis of lung and spleen tissue from patients who died of sepsis revealed certain biochemical, cellular and histological findings that were consistent with immunosuppression, according to a study in the December 21 issue of JAMA.

21 Dec 2011