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Study finds treatment-related mortality with bevacizumab in cancer patients

Cancer patients treated with the chemotherapy agent bevacizumab may be at an increased risk of treatment-related death when the drug is used in combination with other therapies.

2 Feb 2011

Bioengineers and physician-scientists zap tumors with light-activated nanoparticles

Rice University bioengineers and physician-scientists at Baylor College of Medicine and Texas Children's Hospital have successfully destroyed tumors of human brain cancer cells in the first animal tests of a minimally invasive treatment that zaps glioma tumors with heat. The tests involved nanoshells, light-activated nanoparticles that are designed to destroy tumors with heat and avoid the unwanted side effects of drug and radiation therapies.

2 Feb 2011

Quebec provides access to new treatment for women with postmenopausal osteoporosis

Today Quebec is providing access to a therapy in a new class of osteoporosis treatments. With Quebec being the first province to list Prolia on public and private drug plans, Canadians living with osteoporosis in the province of Quebec now have access to increased treatment options.

2 Feb 2011

Scientists discover breast cancer cells that dodge immune system, promote tumor growth

Scientists discovered a new way breast cancer cells dodge the immune system and promote tumor growth, providing a fresh treatment target in the fight against the disease. While comparable mechanisms to avoid the immune system have been identified in mice with breast and other cancers, the study tested human breast tumor cells, putting researchers closer to understanding how the disease progresses in real patients.

2 Feb 2011

Brain surgeon partners with NASA's JPL to design high-tech surgical instruments

Internationally renowned brain surgeon Hrayr Shahinian, M.D., a pioneer in minimally invasive brain surgery, has announced that he is teaming with scientists and technologists at NASA's Jet Propulsion Laboratory in Pasadena, Calif., to design the next generation of high-tech surgical instruments - technology that also will be useful for planetary exploration.

2 Feb 2011

Research discovers new role of TRPV1 receptors in regulation of locomotor activity

Research by a Barrow Neurological Institute scientist on the thermoregulatory effects of a receptor more commonly studied for its role in pain is the cover story in the Feb. 2 issue of the Journal of Neuroscience.

2 Feb 2011

Antares initiates dosing in VIBEX MTX clinical study for rheumatoid arthritis

Antares Pharma, Inc. today announced that the first patient has been dosed in a clinical study evaluating the VIBEX™ MTX product which is being developed for the treatment of rheumatoid arthritis. The clinical study will evaluate several dose strengths of VIBEX MTX delivered with a proprietary autoinjector versus conventional needle and syringe administration by a healthcare professional.

2 Feb 2011

Study finds link between oral health care and heart disease

During American Heart Month in February, United Concordia Dental, one of the nation's largest dental insurers, wants to remind adults that taking care of their teeth and gums is an important part of promoting heart health.

2 Feb 2011

EA sponsors research grant to investigate specific cancers and kinase mutations

Expression Analysis today announced a jointly sponsored research grant for up to eight American Cancer Society Grantees to investigate and draw parallels between specific cancers and recurring mutations in specific kinases, using targeted genome sequencing.

2 Feb 2011

FDA approves Cyberonics Aspire High Capacity generator for vagus nerve stimulation therapy

Cyberonics, Inc. today announced that the AspireHC™ (High Capacity) generator for use in vagus nerve stimulation (VNS) therapy was approved by the United States Food and Drug Administration (FDA) for commercial release.

2 Feb 2011

New compound appears to prevent pain crises in sickle cell disease: GHSU

A new compound appears to prevent the traffic jam of cells that causes debilitating pain crises and associated mortality in sickle cell disease, Georgia Health Sciences University researchers report.

1 Feb 2011

PET imaging may play a role in early evaluation of vandetanib response in thyroid cancer

Positron emission tomography can image metabolic changes following treatment with the protein kinase inhibitor vandetanib, helping to define the therapy response or the effectiveness of the therapeutic agent, according to research published in the February issue of The Journal of Nuclear Medicine.

1 Feb 2011

BioMarin commences GALNS Phase 3 trial in patients with Morquio A Syndrome

BioMarin Pharmaceutical announced today that it has initiated a pivotal Phase 3 trial for N-acetylgalactosamine 6-sulfatase, intended for the treatment of the lysosomal storage disorder Mucopolysaccharidosis Type IVA, also called Morquio A Syndrome.

1 Feb 2011

FDA, Optivia collaborate to examine effect of dietary supplements in drug-induced liver injury

Optivia Biotechnology, a leading provider of in vitro transporter assay services, today announced that the company and the U.S. Food and Drug Administration have signed a collaboration agreement to assess the effect of dietary supplements on key drug transporters.

1 Feb 2011

Intricon introduces new patent-pending APT Open in-the-canal hearing aid

IntriCon Corporation, a designer, developer, manufacturer and distributor of body-worn devices, today announced that it has launched its all-new, patent-pending APT Open in-the-canal hearing aid.

1 Feb 2011

FDA approves NCI's Sodium Fluoride F18 NDA for use in bone scans

The FDA has approved a New Drug Application from the National Cancer Institute, part of the National Institutes of Health, for a new strength of a previously approved drug, Sodium Fluoride F18, for use in bone scans.

1 Feb 2011

Vanderbilt researchers announce multi-national collaboration on Alzheimer's disease genetics

Researchers at Vanderbilt University Medical Center, and across the globe, announced today a multi-national collaboration to discover and map all genes relating to Alzheimer's disease through the formation of the International Genomics of Alzheimer's Project.

1 Feb 2011

Orexigen, Takeda announce FDA's issue of complete response letter for Contrave NDA

Orexigen® Therapeutics, Inc. and Takeda Pharmaceutical Company Limited announced today that the United States Food and Drug Administration (FDA) has issued a complete response letter dated January 31, 2011 regarding the New Drug Application for Contrave® (naltrexone HCl/bupropion HCl) extended-release tablets for the treatment of obesity, including weight loss and maintenance of weight loss.

1 Feb 2011

Study establishes direct link between morphine abstinence and depressive-like symptoms

Opiate abuse is a chronic disorder and maintaining abstinence represents a major challenge for addicts.

1 Feb 2011

AVEO commences enrollment in tivozanib Phase 2 study in renal cell carcinoma

AVEO Pharmaceuticals, Inc. today announced that it has initiated patient enrollment in a multi-center Phase 2 exploratory biomarker study of tivozanib, its lead product candidate designed to optimally block the VEGF pathway by inhibiting all three VEGF receptors, in patients with renal cell carcinoma (RCC).

1 Feb 2011

Medical Condition News

Study finds treatment-related mortality with bevacizumab in cancer patients

Bioengineers and physician-scientists zap tumors with light-activated nanoparticles

Quebec provides access to new treatment for women with postmenopausal osteoporosis

Scientists discover breast cancer cells that dodge immune system, promote tumor growth

Brain surgeon partners with NASA's JPL to design high-tech surgical instruments

Research discovers new role of TRPV1 receptors in regulation of locomotor activity

Antares initiates dosing in VIBEX MTX clinical study for rheumatoid arthritis

Study finds link between oral health care and heart disease

EA sponsors research grant to investigate specific cancers and kinase mutations

FDA approves Cyberonics Aspire High Capacity generator for vagus nerve stimulation therapy

New compound appears to prevent pain crises in sickle cell disease: GHSU

PET imaging may play a role in early evaluation of vandetanib response in thyroid cancer

BioMarin commences GALNS Phase 3 trial in patients with Morquio A Syndrome

FDA, Optivia collaborate to examine effect of dietary supplements in drug-induced liver injury

Intricon introduces new patent-pending APT Open in-the-canal hearing aid

FDA approves NCI's Sodium Fluoride F18 NDA for use in bone scans

Vanderbilt researchers announce multi-national collaboration on Alzheimer's disease genetics

Orexigen, Takeda announce FDA's issue of complete response letter for Contrave NDA

Study establishes direct link between morphine abstinence and depressive-like symptoms

AVEO commences enrollment in tivozanib Phase 2 study in renal cell carcinoma

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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