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Incyte announces additional results from ruxolitinib Phase III trial on myelofibrosis

Incyte Corporation announced today additional symptom improvement and quality of life (QoL) results from COMFORT-I, a randomized, double-blinded, placebo-controlled Phase III trial of Incyte's JAK1 and JAK2 inhibitor, ruxolitinib, in patients with myelofibrosis (MF).

13 Jun 2011

Scientists pioneer way to find more chromosomal aberrations in tumors

Washington University Pediatric Cancer Genome Project scientists pioneer way to find more chromosomal aberrations in tumors; results likely to advance understanding of cancer.

13 Jun 2011

Kurma, CRT launch BliNK Therapeutics to generate monoclonal antibodies

Cancer Research Technology, the commercial arm of Cancer Research UK, and Paris-based venture capital firm, Kurma Life Sciences Partners (Kurma), have launched a spin-out company, BliNK Therapeutics Ltd, to generate monoclonal antibodies using a novel platform.

13 Jun 2011

Seattle Genetics, Millennium ADCETRIS phase I trial data on Hodgkin lymphoma presented at EHA

Millennium: The Takeda Oncology Company, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited and Seattle Genetics, Inc., announced today that data on ADCETRIS (brentuximab vedotin) in relapsed or refractory Hodgkin lymphoma patients were featured in an oral presentation at the 16th Congress of the European Hematology Association (EHA) in London.

13 Jun 2011

Only 35% of anaesthesiologists carry out cardiac output monitoring during high-risk surgery

Only 35% of anaesthesiologists are carrying out a simple procedure during high-risk surgery that can make a significant impact on how well patients recover from their operations, according to new research presented today at the European Anaesthesiology Congress in Amsterdam.

13 Jun 2011

Preliminary results from Edison's EPI-A0001 28-day phase 2A trial against Friedreich's ataxia

Edison Pharmaceuticals, Inc. announced today preliminary results obtained on a 28-day phase 2A clinical trial in Friedreich's ataxia. While the primary endpoint of glucose disposition index did not show statistically significant improvement, EPI-A0001 did significantly improve neurological function as assessed by the Friedreich's Ataxia Rating Scale.

10 Jun 2011

Researchers unearth secret of immune system's success

After eight years of work, researchers have unearthed what has been a well-kept secret of our immune system's success. The findings published online on June 9th in Immunity, a Cell Press publication, offer an explanation for how specialized immune cells are able to kill infected or cancerous cells without killing themselves in the process.

From Evident Corporation - Life Sciences 10 Jun 2011

Vertex VX-770 Phase 3 STRIVE study for cystic fibrosis demonstrates improvements in lung function

Vertex Pharmaceuticals Incorporated today announced the final results from its pivotal Phase 3 STRIVE study that evaluated VX-770, a medicine in development that targets the defective protein that causes cystic fibrosis (CF).

10 Jun 2011

Turning back the clock on aging stem cells to make better bone

Researchers want to turn back the clock on aging stem cells so they'll make better bone.

10 Jun 2011

Hyperthermia prevents repair of tumor cells

BSD Medical Corporation, a leading provider of medical systems that utilize heat therapy to treat cancer, announced today that a study published in the Proceedings of the National Academy of Sciences demonstrated that hyperthermia can be a powerful tool to inhibit the ability of cancer cells to repair the DNA damage caused by radiation or chemotherapy.

10 Jun 2011

Surgeon uses radiotracers to detect the ganglion through which tumour attempts to spread

Dr Naia Uribe-Etxebarria has shown that it is viable to detect the ganglion through which a tumour attempts to spread, using a radiotracer, in a PhD defended at the University of the Basque Country.

10 Jun 2011

MHS wins EPA's 2011 National Environmental Leadership Award in Asthma Management

Centene Corporation announced today that Managed Health Services (MHS), its Indiana subsidiary, won the 2011 National Environmental Leadership Award (Health Plan Division) in Asthma Management from the EPA (Environmental Protection Agency).

10 Jun 2011

Protein missing in fragile X syndrome acts as a molecular toggle switch in brain cells

New research shows how the protein missing in fragile X syndrome - the most common inherited form of intellectual disability - acts as a molecular toggle switch in brain cells.

10 Jun 2011

GE and Mayo Clinic receive $5.7 million NIH grant to study dedicated MRI brain scanner technology

Driving new technologies that will help expand the availability of MRI scanners beyond the hospital to smaller clinic settings, GE Global Research, the technology development arm for the General Electric Company, and Mayo Clinic, have received a five-year, $5.7 million grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), and the National Institute of Neurological Disorders and Stroke (NINDS), components of the National Institutes of Health.

10 Jun 2011

Promising new strategy for treating human type 2 diabetes

In a mouse study, scientists at Mayo Clinic Florida have demonstrated the feasibility of a promising new strategy for treating human type 2 diabetes, which affects more than 200 million people worldwide.

10 Jun 2011

Larger trial study needed to decide fate of niacin

Niaspan is a cholesterol drug manufactured by Abbott Laboratories. Doctors have customarily prescribed Niacin to raise levels of HDL ("good" cholesterol) in patients taking a statin pill that is successfully lowering their LDL ("bad" cholesterol).

10 Jun 2011

Scientists coax tumor cells to grow into 3-D spheres

A team of scientists has developed a way to coax tumor cells in the lab to grow into 3-D spheres. Their discovery takes advantage of an earlier technique of producing spherical cavities in a common polymer and promises more accurate tests of new cancer therapies.

10 Jun 2011

Progressive strength training counteracts muscular atrophy in old age

People lose 30% of their muscle strength between the ages of 50 and 70 years. However, maintaining muscle strength in old age is enormously important in order to maintain mobility and to be able to lead an independent life and manage everyday tasks independently.

10 Jun 2011

Spanish scale measures concern about cancer in healthy people

When a person has a family history of cancer, their worry about developing the disease may lead to them refusing to have preventive tests. Advice from genetic counselling units reduces their anxiety but, until now, nobody knew how much. Now, a scientific team has validated the 'Escala de Preocupaci-n por el C-ncer - EPC' (equivalent of the Cancer Worry Scale), the first of its kind in the Spanish language, in order to evaluate it.

10 Jun 2011

Adaptation of fat cell membranes to obesity may play a key role in early stages of inflammatory disorders

The mechanisms by which obesity leads towards metabolic co-morbidities, such as diabetes mellitus, are poorly understood and of great public health interest. A study led by Matej Orešič from VTT Technical Research Centre of Finland suggests that adaptation of fat cell membranes to obesity may play a key role in the early stages of inflammatory disorders.

10 Jun 2011

Medical Condition News

Incyte announces additional results from ruxolitinib Phase III trial on myelofibrosis

Scientists pioneer way to find more chromosomal aberrations in tumors

Kurma, CRT launch BliNK Therapeutics to generate monoclonal antibodies

Seattle Genetics, Millennium ADCETRIS phase I trial data on Hodgkin lymphoma presented at EHA

Only 35% of anaesthesiologists carry out cardiac output monitoring during high-risk surgery

Preliminary results from Edison's EPI-A0001 28-day phase 2A trial against Friedreich's ataxia

Researchers unearth secret of immune system's success

Vertex VX-770 Phase 3 STRIVE study for cystic fibrosis demonstrates improvements in lung function

Turning back the clock on aging stem cells to make better bone

Hyperthermia prevents repair of tumor cells

Surgeon uses radiotracers to detect the ganglion through which tumour attempts to spread

MHS wins EPA's 2011 National Environmental Leadership Award in Asthma Management

Protein missing in fragile X syndrome acts as a molecular toggle switch in brain cells

GE and Mayo Clinic receive $5.7 million NIH grant to study dedicated MRI brain scanner technology

Promising new strategy for treating human type 2 diabetes

Larger trial study needed to decide fate of niacin

Scientists coax tumor cells to grow into 3-D spheres

Progressive strength training counteracts muscular atrophy in old age

Spanish scale measures concern about cancer in healthy people

Adaptation of fat cell membranes to obesity may play a key role in early stages of inflammatory disorders

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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